RUFY1 (NM_001040452) Human Untagged Clone

CAT#: SC310735

RUFY1 (untagged)-Human RUN and FYVE domain containing 1 (RUFY1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RUFY1
• Synonyms: RABIP4; ZFYVE12
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001040452, the custom clone sequence may differ by one or more nucleotides
  ATGATGGAGGAGCGTGCCAACCTGATGCACATGATGAAACTCAGCATCAAGGTGTTGCTC
  CAGTCGGCTCTGAGCCTGGGCCGCAGCCTGGATGCGGACCATGCCCCCTTGCAGCAGTTC
  TTTGTAGTGATGGAGCACTGCCTCAAACATGGGCTGAAAGTTAAGAAGAGTTTTATTGGC
  CAAAATAAATCATTCTTTGGTCCTTTGGAGCTGGTGGAGAAACTTTGTCCAGAAGCATCA
  GATATAGCGACTAGTGTCAGAAATCTTCCAGAATTAAAGACAGCTGTGGGAAGAGGCCGA
  GCGTGGCTTTATCTTGCACTCATGCAAAAGAAACTGGCAGATTATCTGAAAGTGCTTATA
  GACAATAAACATCTCTTAAGCGAGTTCTATGAGCCTGAGGCTTTAATGATGGAGGAAGAA
  GGGATGGTGATTGTTGGTCTGCTGGTGGGACTCAATGTTCTCGATGCCAATCTCTGCTTG
  AAAGGAGAAGACTTGGATTCTCAGGTTGGAGTAATAGATTTTTCCCTCTACCTTAAGGAT
  GTGCAGGATCTTGATGGTGGCAAGGAGCATGAAAGAATTACTGATGTCCTTGATCAAAAA
  AATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAG
  ATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAAGAAGAGCTTTCAGCTGCAACAGAC
  CGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGA
  GAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACT
  TACAAGCAAACTCGGCAAGGTCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAA
  GAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAA
  ACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACA
  CTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCAC
  AAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAA
  GGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCG
  GAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGG
  AGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAG
  AAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAG
  AAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAG
  TTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAA
  GCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAA
  GAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGT
  AGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGC
  CACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCG
  GTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCC
  TGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001040452
• ORF Size: 1803 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001040452.1, NP_001035542.1
• RefSeq Size: 2439
• RefSeq ORF: 1803
• Locus ID: 80230
• Protein Pathways: Endocytosis
• Gene Summary: This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. Variants 2 and 3 encode the same isoform (b) which has a shorter N-terminus compared to isoform a.