ARAP1 (NM_001040118) Human Untagged Clone

CAT#: SC310920

ARAP1 (untagged)-Human ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (ARAP1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARAP1
• Synonyms: CENTD2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001040118, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGAGGCTGGGGATGCTGCGCTATCGGTGGCCGAGTGGCTGCGGGCATTGCACCTGGAGCAGTACA
  CGGGGCTCTTTGAGCAGCATGGCCTGGTGTGGGCCACTGAGTGCCAAGGCCTCAGCGACACCCGCCTGAT
  GGACATGGGCATGCTACTCCCTGGTCACCGCCGCCGCATCCTGGCTGGCCTGCTCCGTGCCCATACCTCA
  CCGGCCCCTGCACCCCGCCCCACCCCACGGCCTGTGCCCATGAAGCGCCACATCTTCCGCTCACCACCTG
  TGCCTGCCACTCCACCCGAGCCGCTGCCCACCACTACAGAGGATGAGGGGCTCCCCGCTGCCCCACCCAT
  CCCGCCCCGGAGGAGCTGCCTTCCGCCCACCTGCTTCACCACCCCATCCACAGCTGCCCCAGACCCTGTG
  CTGCCCCCGCTGCCTGCTAAGCGGCATTTGGCAGAGCTGAGCGTTCCACCCGTGCCGCCCCGCACCGGAC
  CCCCCCGCCTGCTGGTGAGCCTGCCCACTAAGGAGGAGGAGTCATTGCTGCCATCATTATCATCCCCTCC
  CCAGCCACAGTCTGAGGAGCCCCTGTCCACCCTCCCCCAGGGGCCTCCCCAGCCTCCCTCTCCACCTCCC
  TGCCCCCCGGAGATACCTCCAAAGCCGGTACGCCTGTTCCCAGAGTTCGATGACTCTGACTACGATGAGG
  TCCCAGAGGAGGGGCCGGGGGCCCCAGCCAGAGTGATGACCAAGAAGGAGGAGCCCCCACCGAGCCGAGT
  CCCACGGGCCGTGCGCGTGGCCAGTCTGCTGAGCGAGGGAGAGGAACTGTCTGGGGACGACCAAGGGGAT
  GAGGAAGAGGATGACCACGCCTATGAGGGCGTCCCCAATGGCGGATGGCATACCAGCAGCCTGAGCTTGT
  CCTTGCCCAGCACAATAGCTGCGCCACACCCCATGGACGGGCCGCCTGGGGGCTCCACCCCCGTCACACC
  AGTCATCAAGGCTGGCTGGCTGGACAAGAACCCACCGCAGGGATCTTACATCTATCAGAAACGATGGGTG
  AGACTGGATACTGATCACCTGCGATACTTTGACAGTAACAAGGACGCTTACTCTAAGCGCTTTATCTCTG
  TGGCCTGCATCTCCCACGTGGCTGCCATCGGGGACCAGAAGTTTGAAGTGATCACAAACAACCGAACCTT
  TGCCTTCCGGGCAGAGAGTGATGTGGAGCGGAAGGAGTGGATGCAGGCCCTGCAGCAGGCCATGGCTGAG
  CAGCGTGCCCGGGCCCGGCTCTCTAGCGCTTATCTGCTGGGAGTTCCAGGCTCAGAGCAGCCTGACCGCG
  CTGGCAGCCTGGAGCTTCGTGGCTTCAAGAATAAGCTGTACGTGGCCGTGGTCGGGGACAAAGTGCAGCT
  CTACAAGAATCTAGAGGAGTACCACCTGGGCATTGGCATCACCTTCATCGACATGAGCGTGGGCAACGTG
  AAGGAAGTGGACCGGCGCAGCTTCGACCTCACCACGCCCTACCGCATCTTCAGCTTCTCTGCTGACTCAG
  AGCTAGAGAAGGAGCAGTGGTTGGAGGCCATGCAGGGAGCCATCGCTGAGGCCCTGTCTACCTCGGAGGT
  GGCCGAGCGCATCTGGGCTGCAGCCCCCAACAGGTTCTGTGCTGACTGCGGGGCTCCTCAGCCTGACTGG
  GCCTCCATCAACCTCTGTGTTGTTATCTGCAAGCGCTGTGCAGGGGAGCACCGTGGCCTGGGCGCTGGCG
  TCTCCAAGGTGCGGAGCCTGAAGATGGACAGGAAGGTGTGGACAGAAACACTTATCGAGCTCTTCTTACA
  GCTGGGGAATGGCGCTGGGAACCGCTTCTGGGCAGCCAACGTGCCCCCCAGTGAGGCCCTGCAGCCCAGC
  AGCAGCCCCAGCACCCGGCGGTGCCACCTGGAGGCCAAGTACCGTGAGGGCAAGTACCGCCGCTACCACC
  CGCTCTTTGGCAACCAGGAGGAGCTGGACAAGGCCCTGTGTGCTGCAGTCACCACCACAGACCTGGCTGA
  GACCCAGGCGCTCCTGGGCTGTGGGGCTGGGATCAACTGCTTCTCGGGGGACCCTGAGGCCCCCACGCCC
  CTGGCTCTTGCAGAGCAGGCGGGGCAGACGCTGCAGATGGAATTCCTTCGGAACAACCGGACCACAGAGG
  TGCCTCGGCTGGACTCGATGAAGCCCCTGGAAAAGCACTACTCAGTTGTCCTGCCGACCGTGAGCCACAG
  TGGCTTCCTCTACAAGACTGCCTCTGCCGGCAAGCTGCTACAGGACCGCCGGGCCCGGGAAGAGTTCAGC
  CGGCGCTGGTGTGTCCTTGGTGACGGGGTCCTGAGCTACTTTGAGAATGAGCGGGCAGTGACCCCCAATG
  GAGAGATTCGGGCCAGCGAGATTGTGTGCCTGGCAGTGCCCCCTCCTGACACCCATGGCTTTGAGCACAC
  CTTTGAGGTGTACACGGAGGGAGAACGGCTGTACCTGTTTGGGCTGGAGAGTGCGGAGCAGGCTCATGAG
  TGGGTCAAGTGTATTGCTAAGGCATTCGTGCCTCCCCTAGCCGAGGATCTGCTGGCCCGGGATTTTGAGC
  GGCTGGGACGCCTACCCTACAAAGCTGGCCTGAGCCTACAGCGGGCCCAGGAGGGCTGGTTCTCTCTCAG
  TGGCTCGGAGCTCCGTGCTGTCTTCCCGGAGGGGCCCTGCGAAGAGCCGCTGCAACTACGGAAACTGCAG
  GAGCTTTCCATCCAGGGGGACAGTGAGAACCAGGTGCTGGTGCTGGTGGAGCGAAGGAGGACACTGTACA
  TACAGGGCGAGCGGCGGCTGGACTTCATGGGTTGGCTGGGGGCCATCCAGAAAGCAGCCGCCAGCATGGG
  GGACACGCTGTCGGAGCAGCAGCTTGGGGACTCGGATATCCCGGTGATCGTGTACCGCTGTGTGGACTAC
  ATCACGCAGTGCGGCCTGACCTCCGAGGGCATCTACCGCAAGTGTGGGCAGACATCGAAGACACAGCGGC
  TGCTGGAGAGCCTGCGGCAGGATGCGCGCTCTGTGCACCTCAAGGAGGGCGAGCAGCACGTGGATGATGT
  TTCCTCGGCGCTCAAGCGCTTCCTGCGCGACCTGCCTGATGGGCTCTTCACTCGCGCCCAGCGCCTAACC
  TGGCTGGAGGCCTCAGAGATTGAGGACGAGGAGGAGAAGGTCTCCAGGTACCGAGAGCTGCTGGTGCGGC
  TGCCCCCTGTCAACCGGGCCACAGTGAAGGCCCTTATCAGCCACCTGTACTGTGTTCAGTGCTTCTCAGA
  CACGAACCAGATGAACGTGCACAACCTGGCAATTGTGTTTGGGCCCACGCTCTTCCAGACAGATGGGCAG
  GACTACAAGGCTGGCCGTGTGGTGGAAGACCTCATTAACCACTATGTGGTGGTGTTTAGTGTGGATGAGG
  AAGAGCTCAGGAAGCAGCGGGAGGAGATCACTGCCATTGTGAAGATGCGCGTGGCTGGCACTGCCAGTGG
  GACCCAGCATGCCGGTGACTTCATCTGCACAGTGTATCTGGAAGAGAAGAAGGCAGAGACTGAGCAGCAT
  ATCAAGGTCCCAGCATCCATGACTGCTGAGGAGCTCACCCTGGAGATCCTGGATCGCCGGAACGTGGGCA
  TCAGGGAGAAGGACTATTGGACCTGCTTTGAGGTCAACGAGAGGGAGGAGGCAGAGCGCCCCCTGCACTT
  TGCGGAGAAGGTGCTGCCCATCCTGCACGGGCTGGGCACGGACAGCCACCTGGTGGTGAAGAAGCACCAG
  GCCATGGAGGCCATGCTGCTGTACCTGGCCAGCCGTGTCGGTGACACCAAGCATGGCATGATGAAGTTCC
  GTGAGGACCGCAGCCTCCTGGGCCTGGGCCTGCCCTCAGGTGGCTTCCACGATCGCTACTTCATCCTCAA
  CAGCAGCTGCTTGCGGCTCTACAAGGAGGTCCGGAGCCAGAGGCCGTGGAGCGGGGCCCCTGAGACCAGT
  CACCGGCCTGAGAAGGAGTGGCCTATTAAGAGTCTCAAAGTCTACCTGGGAGTGAAGAAGAAACTCAGGC
  CACCCACCTGCTGGGGCTTCACAGTGGTGCATGAGACAGAGAAACATGAGAAGCAGCAGTGGTACCTCTG
  CTGTGACACACAGATGGAGCTCCGGGAGTGGTTCGCTACCTTTCTGTTTGTGCAGCATGACGGCCTGGTG
  TGGCCCTCAGAGCCCTCACGCGTGTCCCGGGCAGTGCCTGAGGTCCGGCTGGGTAGTGTGTCACTGATCC
  CCCTTCGAGGTAGTGAAAATGAAATGCGCCGGAGTGTGGCTGCCTTCACCGCGGACCCTCTGTCTCTTCT
  GCGCAACGTCTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001040118
• ORF Size: 4353 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001040118.2, NP_001035207.1
• RefSeq Size: 5155
• RefSeq ORF: 4353
• Locus ID: 116985
• Protein Pathways: Endocytosis
• Gene Summary: The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  Transcript Variant: This variant (3) is the longest transcript and it encodes the longest protein (isoform c).