Annexin VIII (ANXA8) (NM_001040084) Human Untagged Clone

CAT#: SC310952

ANXA8 (untagged)-Human annexin A8 (ANXA8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANXA8
• Synonyms: ANX8; CH17-360D5.2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001040084, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCTGGTGGAAATCCTGGATTGAACAGGAGGGTGTCACAGTGAAGAGCAGCTCCCACTTCAACCCAG
  ACCCTGATGCAGAGACCCTCTACAAAGCCATGAAGGGGATCGGGACCAACGAGCAGGCTATCATCGATGT
  GCTCACCAAGAGAAGCAACACGCAGCGGCAGCAGATCGCCAAGTCCTTCAAGGCTCAGTTCGGCAAGGAC
  CTCACTGAGACCTTGAAGTCTGAGCTCAGTGGCAAGTTTGAGAGGCTCATTGTGGCCCTTATGTACCCGC
  CATACAGATACGAAGCCAAGGAGCTGCATGACGCCATGAAGGGCTTAGGAACCAAGGAGGGTGTCATCAT
  TGAGATCCTGGCCTCTCGGACCAAGAACCAGCTGCGGGAGATAATGAAGGCGTATGAGGAAGACTATGGG
  TCCAGCCTGGAGGAGGACATCCAAGCAGACACAAGTGGCTACCTGGAGAGGATCCTGGTGTGCCTCCTGC
  AGGGCAGCAGGGATGATGTGAGCAGCTTTGTGGACCCAGGACTGGCCCTCCAAGACGCACAGGATCTGTA
  TGCGGCAGGCGAGAAGATTCGTGGGACTGATGAGATGAAATTCATCACCATCCTGTGCACGCGCAGTGCC
  ACTCACCTGCTGAGAGTGTTTGAAGAGTATGAGAAAATTGCCAACAAGAGCATTGAGGACAGCATCAAGA
  GTGAGACCCATGGCTCACTGGAGGAGGCCATGCTCACTGTGGTGAAATGCACCCAAAACCTCCACAGCTA
  CTTTGCAGAGAGACTCTACTATGCCATGAAGGGAGCAGGGACGCGTGATGGGACCCTGATAAGAAACATC
  GTTTCAAGGAGCGAGATTGACTTAAATCTTATCAAATGTCACTTCAAGAAGATGTACGGCAAGACCCTCA
  GCAGCATGATCATGGAAGACACCAGCGGTGACTACAAGAACGCCCTGCTGAGCCTGGTGGGCAGCGACCC
  CTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001040084
• ORF Size: 984 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001040084.2, NP_001035173.1
• RefSeq Size: 2070
• RefSeq ORF: 984
• Locus ID: 653145
• Gene Summary: This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. It encodes isoform 2, which has a shorter N-terminus compared to isoform 1. An in-frame AUG is located 66 codons upstream of the annotated translation start site but was not annotated as a start site since it is not conserved and is in a weak Kozak sequence context.