5HT4 Receptor (HTR4) (NM_001040172) Human Untagged Clone

CAT#: SC311002

HTR4 (untagged)-Human 5-hydroxytryptamine (serotonin) receptor 4 (HTR4), transcript variant d

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HTR4
• Synonyms: 5-HT4; 5-HT4R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001040172 edited
  CGCAGGCAGCGGCTGGGAGCGCAGCGGCAGCGGCGGCAGCAGAAGCTCGGCTCAGCGGCT
  GGGGGTGGCCGCTCGAATCTGCCAGGGCACCTCGCTCCCTCGCCTCTGGCAGCGGGACCC
  TGTGGGCATTGAAATCCAACTCACTCATGCTTATTTCCTGTAATGGACAAACTTGATGCT
  AATGTGAGTTCTGAGGAGGGTTTCGGGTCAGTGGAGAAGGTGGTGCTGCTCACGTTTCTC
  TCGACGGTTATCCTGATGGCCATCTTGGGGAACCTGCTGGTGATGGTGGCTGTGTGCTGG
  GACAGGCAGCTCAGGAAAATAAAAACAAATTATTTCATTGTATCTCTTGCTTTTGCGGAT
  CTGCTGGTTTCGGTGCTGGTGATGCCCTTTGGTGCCATTGAGCTGGTTCAAGACATCTGG
  ATTTATGGGGAGGTGTTTTGTCTTGTTCGGACATCTCTGGACGTCCTGCTCACAACGGCA
  TCGATTTTTCACCTGTGCTGCATTTCTCTGGATAGGTATTACGCCATCTGCTGCCAGCCT
  TTGGTCTATAGGAACAAGATGACCCCTCTGCGCATCGCATTAATGCTGGGAGGCTGCTGG
  GTCATCCCCACGTTTATTTCTTTTCTCCCTATAATGCAAGGCTGGAATAACATTGGCATA
  ATTGATTTGGAAAGGAGTCTAAACCAAGGCCTGGGCCAGGATTTTCATGCGATAGAAAAG
  AGGAAGTTCAACCAGAACTCTAACTCTACGTACTGTGTCTTCATGGTCAACAAGCCCTAC
  GCCATCACCTGCTCTGTGGTGGCCTTCTACATCCCATTTCTCCTCATGGTGCTGGCCTAT
  TACCGCATCTATGTCACAGCTAAGGAGCATGCCCATCAGATCCAGATGTTACAACGGGCA
  GGAGCCTCCTCCGAGAGCAGGCCTCAGTCGGCAGACCAGCATAGCACTCATCGCATGAGG
  ACAGAGACCAAAGCAGCCAAGACCCTGTGCATCATCATGGGTTGCTTCTGCCTCTGCTGG
  GCACCATTCTTTGTCACCAATATTGTGGATCCTTTCATAGACTACACTGTCCCTGGGCAG
  GTGTGGACTGCTTTCCTCTGGCTCGGCTATATCAATTCCGGGTTGAACCCTTTTCTCTAC
  GCCTTCTTGAATAAGTCTTTTAGACGTGCCTTCCTCATCATCCTCTGCTGTGATGATGAG
  CGCTACCGAAGACCTTCCATTCTGGGCCAGACTGTCCCTTGTTCAACCACAACCATTAAT
  GGATCCACACATGTACTAAGGGATGCAGTGGAGTGTGGTGGCCAGTGGGAGAGTCAGTGT
  CACCCGCCAGCAACTTCTCCTTTGGTGGCTGCTCAGCCCAGTGACACTTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001040172
• Insert Size: 1400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: ORF was exactly matches with that of NM_001040172.1.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001040172.1, NP_001035262.1
• RefSeq Size: 3023 bp
• RefSeq ORF: 1209 bp
• Locus ID: 3360
• Cytogenetics: 5q32
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: 'This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]'
  Transcript Variant: This variant (d) differs in the 5' UTR and uses an alternate 3' terminal exon compared to variant b. The encoded isoform (d) has a distinct C-terminus and is shorter than isoform b.