Rho GTPase activating protein 24 (ARHGAP24) (NM_001042669) Human Untagged Clone

CAT#: SC311403

ARHGAP24 (untagged)-Human Rho GTPase activating protein 24 (ARHGAP24), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARHGAP24
• Synonyms: FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001042669, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACAGCAAATCATGAAAGCTACCTCCTCATGGCAAGCACCCAGAATGATATGGAAGACTGGGTGAAGT
  CAATCCGCCGAGTCATATGGGGACCTTTCGGAGGAGGCATTTTTGGACAGAAACTGGAGGATACTGTTCG
  TTATGAGAAGAGATATGGGAACCGTCTGGCTCCGATGTTGGTGGAGCAGTGCGTGGACTTTATCCGACAA
  AGGGGGCTGAAAGAAGAGGGTCTCTTTCGACTGCCAGGCCAGGCTAATCTTGTTAAGGAGCTCCAAGATG
  CCTTTGACTGTGGGGAGAAGCCATCATTTGACAGCAACACAGATGTACACACGGTGGCATCACTTCTTAA
  GCTGTACCTCCGAGAACTTCCAGAACCAGTTATTCCTTATGCGAAGTATGAAGATTTTTTGTCATGTGCC
  AAACTGCTCAGCAAGGAAGAGGAAGCAGGTGTTAAGGAATTAGCAAAGCAGGTGAAGAGTTTGCCAGTGG
  TAAATTACAACCTCCTCAAGTATATTTGCAGATTCTTGGATGAAGTACAGTCCTACTCGGGAGTTAACAA
  AATGAGTGTGCAGAACTTGGCAACGGTCTTTGGTCCTAATATCCTGCGCCCCAAAGTGGAAGATCCTTTG
  ACTATCATGGAGGGCACTGTGGTGGTCCAGCAGTTGATGTCAGTGATGATTAGCAAACATGATTGCCTCT
  TTCCCAAAGATGCAGAACTACAAAGCAAGCCCCAAGATGGAGTGAGCAACAACAATGAAATTCAGAAGAA
  AGCCACCATGGGGCAGTTACAGAACAAGGAGAACAATAACACCAAGGACAGCCCTAGTAGGCAGTGCTCC
  TGGGACAAGTCTGAGTCACCCCAGAGAAGCAGCATGAACAATGGATCCCCCACAGCTCTATCAGGCAGCA
  AAACCAACAGCCCAAAGAACAGTGTTCACAAGCTAGATGTGTCTAGAAGCCCCCCTCTCATGGTCAAAAA
  GAACCCAGCCTTTAATAAGGGTAGTGGGATAGTTACCAATGGGTCCTTCAGCAGCAGTAATGCAGAAGGT
  CTTGAGAAAACCCAAACCACCCCCAATGGGAGCCTACAGGCCAGAAGGAGCTCTTCACTGAAGGTATCTG
  GTACCAAAATGGGCACGCACAGTGTACAGAATGGAACGGTGCGCATGGGCATTTTGAACAGCGACACACT
  CGGGAACCCCACAAATGTTCGAAACATGAGCTGGCTGCCAAATGGCTATGTGACCCTGAGGGATAACAAG
  CAGAAAGAACAAGCTGGAGAGTTAGGCCAGCACAACAGACTGTCCACCTATGATAATGTCCATCAACAGT
  TCTCCATGATGAACCTTGATGACAAGCAGAGCATTGACAGTGCTACCTGGTCCACTTCCTCCTGTGAAAT
  CTCCCTCCCTGAGAACTCCAACTCCTGTCGCTCTTCTACCACCACCTGCCCAGAGCAAGACTTTTTTGGG
  GGGAACTTTGAGGACCCTGTTTTGGATGGGCCCCCGCAGGACGACCTTTCCCACCCCAGGGACTATGAAA
  GCAAAAGTGACCACAGGAGTGTGGGAGGTCGAAGTAGTCGTGCCACCAGTAGCAGTGACAACAGTGAGAC
  ATTTGTGGGCAACAGCAGCAGCAACCACAGTGCACTGCACAGTTTAGTTTCCAGCCTGAAACAGGAAATG
  ACCAAACAGAAGATAGAGTATGAGTCCAGGATAAAGAGCTTAGAACAGCGAAACTTGACTTTGGAAACAG
  AAATGATGAGCCTCCATGATGAACTGGATCAGGAGAGGAAAAAGTTCACAATGATAGAAATAAAAATGCG
  AAATGCCGAGCGAGCAAAAGAAGATGCCGAGAAAAGAAATGACATGCTACAGAAAGAAATGGAGCAGTTT
  TTTTCCACGTTTGGAGAACTGACAGTGGAACCCAGGAGAACCGAGAGAGGAAACACAATATGGATTCAGT
  GA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001042669
• ORF Size: 1962 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001042669.1, NP_001036134.1
• RefSeq Size: 4195
• RefSeq ORF: 1962
• Locus ID: 83478
• Gene Summary: This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
  Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.