ABCG8 (NM_022437) Human Untagged Clone

CAT#: SC311404

ABCG8 (untagged)-Human ATP-binding cassette, sub-family G (WHITE), member 8 (ABCG8)


  "NM_022437" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ABCG8
Synonyms GBD4; STSL
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_022437 edited
ATGGCCGGGAAGGCGGCAGAGGAGAGAGGGCTGCCGAAAGGGGCCACTCCCCAGGATACC
TCGGGCCTCCAGGATAGATTGTTCTCCTCTGAAAGTGACAACAGCCTGTACTTCACCTAC
AGTGGCCAGCCCAACACCCTGGAGGTCAGAGACCTCAACTGCCAGGTGGACCTGGCCTCT
CAGGTCCCTTGGTTTGAGCAGCTGGCTCAGTTCAAGATGCCCTGGACATCTCCCAGCTGC
CAGAATTCTTGTGAGCTGGGCATCCAGAACCTAAGCTTCAAAGTGAGAAGTGGGCAGATG
CTGGCCATCATAGGGAGCTCAGGTTGTGGGAGAGCCTCCTTGCTAGATGTGATCACTGGC
CGAGGTCACGGCGGCAAGATCAAGTCAGGCCAGATCTGGATCAATGGGCAGCCCAGCTCG
CCTCAGCTGGTGAGGAAGTGTGTGGCCCACGTGCGCCAGCACAACCAGCTGCTCCCCAAC
TTGACTGTGCGAGAGACCTTGGCCTTCATTGCCCAGATGCGGCTGCCCAGAACCTTCTCC
CAGGCCCAGCGTGACAAAAGGGTGGAGGACGTGATCGCGGAGCTGCGGCTTAGGCAGTGC
GCTGACACCCGCGTGGGCAACATGTACGTGCGGGGGTTGTCGGGGGGTGAGCGCAGGAGA
GTCAGCATTGGGGTGCAGCTCCTGTGGAACCCAGGAATCCTTATTCTCGACGAACCCACC
TCTGGGCTCGACAGCTTCACAGCCCACAACCTGGTGAAGACCTTGTCCAGGCTGGCCAAA
GGCAACCGGCTGGTGCTCATCTCCCTCCACCAGCCTCGCTCTGACATCTTCAGGCTGTTT
GATCTGGTCCTCCTGATGACGTCTGGCACCCCCATCTACTTAGGGGCGGCCCAGCACATG
GTCCAGTATTTCACAGCCATCGGCTACCCCTGTCCTCGCTACAGCAATCCTGCTGACTTC
TATGTGGACCTGACCAGCATTGACAGGCGCAGCAGAGAGCAGGAATTGGCCACCAGGGAG
AAGGCTCAGTCACTCGCAGCCCTGTTTCTAGAAAAAGTGCGTGACTTAGATGACTTTCTA
TGGAAAGCAGAGACGAAGGATCTTGACGAGGACACCTGTGTGGAAAGCAGCGTGACCCCA
CTAGACACCAACTGCCTCCCGAGTCCTACGAAGATGCCTGGGGCGGTGCAGCAGTTTACG
ACGCTGATCCGTCGTCAGATTTCCAACGACTTCCGAGACCTGCCCACCCTCCTCATCCAT
GGGGCGGAGGCCTGTCTGATGTCAATGACCATCGGCTTCCTCTATTTTGGCCATGGGAGC
ATCCAGCTCTCCTTCATGGATACAGCCGCCCTCTTGTTCATGATCGGTGCTCTCATCCCT
TTCAACGTCATTCTGGATGTCATCTCCAAATGTTACTCAGAGAGGGCAATGCTTTACTAT
GAACTGGAAGACGGGCTGTACACCACTGGTCCATATTTCTTTGCCAAGATCCTCGGGGAG
CTTCCGGAGCACTGTGCCTACATCATCATCTACGGGATGCCCACCTACTGGCTGGCCAAC
CTGAGGCCAGGCCTCCAGCCCTTCCTGCTGCACTTCCTGCTGGTGTGGCTGGTGGTCTTC
TGTTGCAGGATTATGGCCCTGGCCGCCGCGGCCCTGCTCCCCACCTTCCACATGGCCTCC
TTCTTCAGCAATGCCCTCTACAACTCCTTCTACCTCGCCGGGGGCTTCATGATAAACTTG
AGCAGCCTGTGGACAGTGCCCGCGTGGATTTCCAAAGTGTCCTTCCTGCGGTGGTGTTTT
GAAGGGCTGATGAAGATTCAGTTCAGCAGAAGAACTTATAAAATGCCTCTCGGGAACCTC
ACCATCGCGGTCTCAGGAGATAAAATCCTCAGTGCCATGGAGCTGGACTCGTACCCTCTC
TACGCCATCTACCTCATCGTCATTGGCCTCAGCGGTGGCTTCATGGTCCTGTACTACGTG
TCCTTAAGGTTCATCAAACAGAAACCAAGTCAAGACTGGTGATTCACGCCAGACGTCTGC
CCGCTGGTGGGGGACCTGAGCAGACCCTTCAACTGCACTCCCTCCTCAGGAGCCCCTTCC
TGGGGACAGTGAGGACAATGACCCTACAGATGCTCAGCTACATCCGGCCCAGGGTGCTGC
AGTGGCACAGACCAGCCACAGGATGGCAGTAGAATAAAGACAGTCGAAAGGGATTTCTGC
TCACTGGCAGGAGACTGCGATGACTGGGAGAAAACCTGCACTCGGTGGCACCTACAACGT
TGCTAATTTATTTCCTTTTGATAGGCATTTAAATAGGCAACTCGATATAGGATGGGAGCA
AACTAGGAATGAATTGGGTAGCTAGACTGTGCAGGAATTGTTGGAACCTGGAGGGAACAA
TAACAGTAGCTAGCAGATTTGGCTTCATCTTCCAGGGGCCCCACACTCCGTGGTGAGCCC
CCATCAATACAGAAAGTGACCTAAGATGTACCAGCAAGATGCCATCCCTTCTTTTTGTGT
GGGGTCATGGGCTCCAAAAGCCAACGTGAACAATTAAAAATGTATTGAGCATTTACTCTG
TAGCAGGTCCTGTGAAAACACTTTAGGTGGACAATCCCTTGAGGTAAAGGGTATCCCATT
TTATAGGTGTGAAAACTGAAGCAAAAATTCATTTTCTTAAGGGCAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_022437 unedited
NNGGTTTAGTTCAGAATTGTATACCATCATATAGGCGGCCGCGNAATTCGCACGAGGATG
GCCGGGAAGGCGGCAGAGAGAGAGGCTGCCGAAGGGGCCACTCCCCAGGATACCTCGGGC
CTCCAGGATAGATTGTTCTCCTCTGAAAGTGACAACAGCCTGTACTTCACCTACAGTGGC
CAGCCCAACACCCTGGAGGTCAGAGACCTCAACTGCCAGGTGGACCTGGCCTCTCAGGTC
CCTTGGTTTGAGCAGCTGGCTCAGTTCAAGATGCCCTGGACATCTCCCAGCTGCCAGAAT
TCTTGTGAGCTGGGCATCCAGAACCTAAGCTTCAAAGTGAGAAGTGGGCAGATGCTGGCC
ATCATAGGGAGCTCAGGTTGTGGGAGAGCCTCCTTGCTAGATGTGATCACTGGCCGAGGT
CACGGCGGCAAGATCAAGTCAGGCCAGATCTGGATCAATGGGCAGCCCAGCTCGCCTCAG
CTGGTGAGGAAGTGTGTGGCCCACGTGCGCCAGCACAACCAGCTGCTCCCCAACTTGACT
GTGCGAGAGACCTTGGCCTTCATTGCCCAGATGCGGCTGCCCAGAACCTTCTCCCAGGCC
CAGCGTGACAAAAGGGTGGAGGACGTGATCGCGGAGCTGCGGCTTAAGCAGTGCGCTGAC
ACCCGCGTGGGCAACATGTACGTGCGGNGGTTGTNCGGGGGTGAGCGCANGAGAGTCAGC
ATTTGGGTGCAGCTTCTGTGNGACCCAGGAATCCTTATTCTCGACGACCCACCTCTGGGC
TCGACAGCTTCACAGCCCACAACCTGGTGAAAGACCCTGTNCAGNCTGGCCAAAGGCACC
CGC
>OriGene 3' genomic read for NM_022437 unedited
CCTTGGGGTGGCAATTCCCATTCCAGNNGNAGCACTGGGGCGGGGTCACAGGGNTGCCAC
CCGGGATCTGTTCAGGAAAAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCCCTTAGGAAAATGAATTTTTGCTTC
AGTTTTCACACCTATAAAATGGGATACCATTTTCCTCAAGGGATTGTCCACCTAAAGTGT
TTTCACAGGACCTGCTACAGAGTAAATGCTCAATACATTTTTAATTGTTCACGTTGGCTT
TTGGAGCCCATGACCCCACACAAAAAGAAGGGATGGCATCTTGCTGGGACATCTTAAGTC
ACTTTCTGTATTGGTGGGGGCTCACCACGGAGTGTGGGGCCCCTGGAAGATGAAGCCAAA
TCTGCTAGCTACTGGTATTGTTCCCTCCAGGTTCCAACAATTCCTGGACAGTCTAGCTAC
CCAATTCATTCCTAGTTTGCTCCCATCCTATATCGAGTTGCCTATATTAATGCCTATCAA
AAGGGAATAAATTAGCAACGTTGTAGGTGCCACCGAGTGCAGGTTTTCTCCCAGTCATCG
CAGTCTCCTGCCAGGGAGCAGAAATCCCTTTGGACTGTCTTTATTTTACTGGCCTCCTGG
GGCTGGGCTGGGGCCCTTGAGCACCCTGGGCCGGATGTAACTTGACCTTTGGGGGGGCAT
TGGCCTCACTGTCCCCAAGAAGGGGCTCCTGAAGGAGGGAGTGCAGTTTAAGGGTTTTGC
TCAGTCCCCCACCAAGGGGGAAAACTTTTTGGCGTGAATTACCAAGGTTTGGT
Restriction Sites Please inquire     
ACCN NM_022437
ORF Size 2022 bp
Insert Size 2800
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_022437.2, NP_071882.1
RefSeq Size 2679
RefSeq ORF 2022
Locus ID 64241
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters
Gene Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) encodes the longer isoform (1).

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