SCN3B (NM_018400) Human Untagged Clone

CAT#: SC312490

SCN3B (untagged)-Human sodium channel, voltage-gated, type III, beta (SCN3B), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCN3B
• Synonyms: ATFB16; BRGDA7; HSA243396; SCNB3
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_018400 edited
  ATGCCTGCCTTCAATAGATTGTTTCCCCTGGCTTCTCTCGTGCTTATCTACTGGGTCAGT
  GTCTGCTTCCCTGTGTGTGTGGAAGTGCCCTCGGAGACGGAGGCCGTGCAGGGCAACCCC
  ATGAAGCTGCGCTGCATCTCCTGCATGAAGAGAGAGGAGGTGGAGGCCACCACGGTGGTG
  GAATGGTTCTACAGGCCCGAGGGCGGTAAAGATTTCCTTATTTACGAGTATCGGAATGGC
  CACCAGGAGGTGGAGAGCCCCTTTCAGGGGCGCCTGCAGTGGAATGGCAGCAAGGACCTG
  CAGGACGTGTCCATCACTGTGCTCAACGTCACTCTGAACGACTCTGGCCTCTACACCTGC
  AATGTGTCCCGGGAGTTTGAGTTTGAGGCGCATCGGCCCTTTGTGAAGACGACGCGGCTG
  ATCCCCCTAAGAGTCACCGAGGAGGCTGGAGAGGACTTCACCTCTGTGGTCTCAGAAATC
  ATGATGTACATCCTTCTGGTCTTCCTCACCTTGTGGCTGCTCATCGAGATGATATATTGC
  TACAGAAAGGTCTCAAAAGCCGAAGAGGCAGCCCAAGAAAACGCGTCTGACTACCTTGCC
  ATCCCATCTGAGAACAAGGAGAACTCTGCGGTACCAGTGGAGGAATAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018400 unedited
  CCGCCGTTGAGCAATGGGCGGTAGGCGTGGATGATGGGAGGTCTATATAAGCAGAGCTCA
  TTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGC
  ACGAGGCGGCCCCGCTGCACCTCCCCAGGGAGCCGAGGGCGGGCGTGGACGGGACCGACG
  TGGAACGCATTCTGTAGCCCAGACGGGCGGCCCCGGCGGCTTCGGGAGTGGGGTCACGCC
  CAGCTGGAGAAGCAGTTAGGGCGGACGAAGCAGGAGCCGCGGGGCTGGGAGGATTCCAGT
  CGGAACGCAACCGATCCTGGGGAGGCGAGAGGTGAATCAACCTGGACCCTTCCACAGCCT
  GGCTGCTAGGCCAGCAGTGCGACTCCCTTCCGAGCTGAGCTTACCCTGGGCGCAAACGAG
  CGAGGCAGGGGCGCGAGTGGAAGCTGGAGTTCCGGGGTGGGCGGGGAGGCGACTGTCCGT
  GGTGCTGAGCGCCGGCGAGAGCGGGCGCGGAGCGGCTGATCGGCTCCCTCGAACTGGGGA
  GGTCCAGTGGGGTCGCTTAGGGCCCAAAGCCCCCACCCGGCTCCAAAAGCTCCCAGGGCC
  TCCCCAGGCACCGGTGCTCGGCCCTTCCTTCGGTCAGAAAGTCGCCCCCTGGGGGCAGTT
  CGTCCCAAAGGGTTTCCTCGAAAGAATCTGAGAGGGCGCAGTCCTTGACCGAGGGAATCT
  CTCTGTGTAGCCTTGGAAGCCGCCAGCCCCAGAAGATGCCTGCCTTCAATAGATTGTTTC
  CCCTGGCTTCTCTCGTGCTTATCTACTGGGTCAGTGTCTGCTTCCCTGTGTGTGTGGAAG
  TGCCCTCGAGACGAGCCGTGCAGGGCAACCCCATGAAGCTGCGCTGCATCTCCTGCATGA
  GAGGAGAGGAGGTGGAGGCCACCACCGGTGGTGGAATGGTTCTACAGGCCCGGAGGGGCG
  GTAAAGAATTTCCTTTATTTACG
  
  3' Read Nucleotide Sequence

  >Forward primer walk for NM_018400 unedited
  TTGCTTCCTGTGTGTGTGGAGTGCCCTCGGTGACGGAGGCCGTGCAGGGCAACCCCATGA
  AGCTGCGCTGCATCTCCTGCATGAAGAGAGAGGAGGTGGAGGCCACCACGGTGGTGGAAT
  GGTTCTACAGGCCCGAGGGCGGTAAAGATTTCCTTATTTACGAGTATCGGAATGGCCACC
  AGGAGGTGGAGAGCCCCTTTCAGGGGCGCCTGCAGTGGAATGGCAGCAAGGACCTGCAGG
  ACGTGTCCATCACTGTGCTCAACGTCACTCTGAACGACTCTGGCCTCTACACCTGCAATG
  TGTCCCGGGAGTTTGAGTTTGAGGCGCATCGGCCCTTTGTGAAGACGACGCGGCTGATCC
  CCCTAAGAGTCACCGAGGAGGCTGGAGAGGACTTCACCTCTGTGGTCTCAGAAATCATGA
  TGTACATCCTTCTGGTCTTCCTCACCTTGTGGCTGCTCATCGAGATGATATATTGCTACA
  GAAAGGTCTCAAAAGCCGAAGAGGCAGCCCAAGAAAACGCGTCTGACTACCTTGCCATCC
  CATCTGAGAACAAGGAGAACTCTGCGGTACCAGTGGAGGAATAGAACAGGAGCAGTGTGA
  CATGAGGTGGCCTGAACACCTGAGGGACTGGACATCCCATGTTCAGCAATGTCAATGGCA
  TCAGAGGGCGCCCCAAGGGCCCCATCGCTTCCCTTCATGCATCCATTGTTCTGTTCATTC
  ATTCATCCATACATCCACCTGCCTCTGAGCTTTCACCTCTGACTCCCTAACTCCATCAGA
  CCTCTACGCCCCATAGACTCTGCCAGACTGAGAGCCAACATTTCTACATAGACTCAACCT
  CACCCTCTCCTAGTTTTCCAACAAGACACTCCAAAGCCAAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018400
• ORF Size: 648 bp
• Insert Size: 6000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_018400.3, NP_060870.1
• RefSeq Size: 6081
• RefSeq ORF: 648
• Locus ID: 55800
• Domains: ig, IG
• Protein Families: Druggable Genome, Ion Channels: Sodium, Transmembrane
• Gene Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript.