Nesprin 2 (SYNE2) (NM_182910) Human Untagged Clone

CAT#: SC313423

SYNE2 (untagged)-Human spectrin repeat containing, nuclear envelope 2 (SYNE2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SYNE2
• Synonyms: EDMD5; KASH2; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; TROPH
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_182910, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAGGTGACAGGAATGTTCCACCTGTTCCCCCTGCGTCCAGCACCCCTTATAAACCACCCTATGGAA
  AGCTACTATTACCTCCAGGCACGGATGGTGGCAAAGAAGGCCCGCGAGTCCTGAATGGCAACCCACAGCA
  GGAAGACGGGGGACTGGCCGGTATCACAGAGCAGCAGTCAGGTGCCTTCGACAGATGGGAGATGATTCAA
  GCACAGGAGCTTCACAATAAGCTCAAAATAAAACAAAATTTGCAACAGCTGAACTCTGATATCAGCGCCA
  TCACTACTTGGCTGAAAAAAACTGAAGCAGAGCTGGAAATGTTAAAGATGGCAAAGCCTCCCTCTGATAT
  CCAGGAAATAGAACTGAGAGTGAAGAGACTGCAGGAGATACTGAAAGCCTTTGACACTTACAAGGCATTA
  GTGGTCTCTGTCAACGTGAGCAGCAAGGAATTTCTGCAAACCGAGAGCCCCGAATCCACAGAGCTCCAAA
  GTAGACTCCGCCAGCTGAGCCTGCTCTGGGAAGCAGCACAGGGCGCAGTGGACAGCTGGAGAGGGGGCTT
  ACGACAGTCGCTCATGCAGTGCCAGGGCTCTAAGACACGGCCGCGCTCTGATGTGTTGTTTTTTAAGGAC
  TTCCACCAGTTGAGTCAAAATCTGCTGCTGTGGTTAGCGAGTGCCAAGAACCGGAGGCAGAAGGCTCATG
  TCACCGATCCAAAGGCAGACCCCCGGGCTCTCCTAGAGTGTCGGAGGGAACTAATGCAACTGGAAAAGGA
  GCTGGTAGAACGTCAACCTCAAGTGGACATGTTACAGGAGATTTCAAACAGCCTTCTCATTAAGGGACAT
  GGAGAAGACTGTATTGAAGCTGAAGAAAAGGTGCATGTTATTGAGAAGAAACTCAAACAGTTACGGGAGC
  AAGTGTCCCAAGATTTAATGGCCTTGCAGGGAACCCAGAACCCAGCCTCACCCCTGCCCAGCTTCGACGA
  GGTAGACTCGGGGGACCAGCCTCCTGCAACATCCGTGCCAGCTCCCCGAGCAAAGTTCAGAGCAGTGAGA
  ACTACAGAAGGCGAGGAGGAGACAGAGAGCAGGGTCCCCGGCAGCACACGGCCACAGCGCTCCTTCCTCT
  CAAGGGTGGTCCGGGCAGCCCTACCCCTGCAGCTGCTCCTCCTGCTGCTGCTGCTCCTGGCCTGCCTGCT
  GCCCTCCTCCGAAGAAGACTACAGCTGCACTCAGGCCAACAACTTTGCCCGGTCCTTTTACCCCATGCTG
  AGGTACACCAATGGGCCACCCCCCACATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_182910
• ORF Size: 1290 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_182910.2, NP_878914.1
• RefSeq Size: 2586
• RefSeq ORF: 1290
• Locus ID: 23224
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 5. The resulting isoform (2) is shorter at the N-terminus compared to isoform 5.