XRN1 (AK096177) Human Untagged Clone
CAT#: SC313624
(untagged)-Human cDNA FLJ38858 fis, clone MESAN2011627, highly similar to 5'-3' exoribonuclease 1
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | XRN1 |
Synonyms | SEP1 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for AK096177, the custom clone sequence may differ by one or more nucleotides
|
Restriction Sites | Please inquire |
ACCN | AK096177 |
ORF Size | 1537 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Reference Data | |
RefSeq | AK096177.1, BAC04718.1 |
RefSeq Size | 1537 |
RefSeq ORF | 1537 |
Locus ID | 54464 |
Domains | XRN_N |
Protein Pathways | RNA degradation |
Gene Summary | This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
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