D2HGDH (BC036604) Human Untagged Clone

CAT#: SC313834

D2HGDH (untagged)-Homo sapiens, clone IMAGE:5274813, partial cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: D2HGDH
• Synonyms: D-2-hydroxyglutarate dehydrogenase; D2HGD; FLJ42195; MGC25181
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for BC036604, the custom clone sequence may differ by one or more nucleotides
  ATGCTGCCCCGTCGGCCTCTGGCGTGGCCCGCGTGGCTGTTGCGGGGTGCTCCGGGAGCC
  GCGGGTTCTTGGGGTCGGCCGGTTGGCCCCCTGGCCCGCAGAGGCTGCTGCTCCGCCCCG
  GGGACCCCCGAGGTGCCGCTGACCCGGGAGCGCTACCCCGTGCAGCGCTTGCCGTTCTCC
  ACGGTGTCTAAGCAGGACCTGGCCGCCTTTGAGCGCATCGTGCCCGGCGGGGTCGTCACG
  GACCCGGAAGCGCTGCAGGCTCCCAACGTGGACTGGTTGCGGACGCTGCGAGGCTGTAGC
  AAGGTGCTGCTGAGGCCACGGACGTCGGAGGAGGTGTCCCACATCCTCAGGCACTGCCAC
  GAGAGGAACCTGGCCGTGAACCCACAGGGGGGCAACACAGGCATGGTGGGTGGCAGCGTC
  CCCGTCTTTGACGAGATCATCCTCTCCACTGCCCGCATGAACCGGGTCCTCAGCTTCCAC
  AGCGTGTCTGGAATTCTGGTTTGCCAGGCGGGCTGCGTCCTGGAGGAGCTGAGCCGGTAT
  GTGGAGGAACGGGACTTCATCATGCCGCTGGACTTAGGAGCCAAGGGCAGCTGCCACATC
  GGGGGAAACGTGGCAACCAACGCTGGAGGCCTGCGGTTTCTTCGATATGGCTCACTGCAT
  GGGACTGTCCTGGGCCTGGAAGTGGTGCTGGCCGACGGCACTGTCCTGGACTGCCTGACC
  TCCCTGAGGAAGGACAACACGGGCTATGACCTGAAGCAGCTGTTCATCGGGTCGGAGGGC
  ACTTTGGGGATCATCACCACGGTGTCCATCTTGTGTCCACCCAAGCCCAGGGCTGTGAAC
  GTGGCTTTCCTCGGCTGCCCAGGCTTTGCTGAGGTTCTGCAGACCTTCAGCACCTGCAAG
  GGGATGCTGGGTGAGATCCTGTCTGCATTCGAGTTCATGGATGCTGTGTGCATGCAGCTG
  GTCGGGCGCCATCTCCACCTGGCCAGCCCGGTGCAAGAGAGTCCGTTTTACGTCCTCATC
  GAGACTTCAGGCTCCAACGCAGGCCATGACGCTGAGAAGCTGGGCCACTTCCTGGAGCAC
  GCGCTGGGCTCCGGCCTGGTGACCGATGGGACCATGGCCACCGACCAGAGGAAAGTCAAG
  ATGCTGTGGGCCCTGAGGGAAAGGATCACAGAGGCGCTGAGCCGGGATGGCTACGTGTAC
  AAGTACGACCTCTCCCTCCCTGTGGAGCGGCTCTACGACATCGTGACTGACCTGCGCGCC
  CGCCTCGGCCCGCACGCCAAGCACGTGGTGGGCTATGGCCACCTTGGAGATGGTAACCTG
  CACCTCAATGTGACGGCGGAGGCCTTCAGCCCCTCGCTCCTGGCTGCCCTGGAGCCCCAC
  GTGTACGAGTGGACGGCCGGGCAGCAGGGCAGCGTCAGCGCGGAGCACGGAGTGGGCTTC
  AGGAAGAGGGACGTCCTGGGCTACAGCAAGCCACCGGGGGCCCTGCAGCTCATGCAGCAG
  CTCAAGGCCCTGCTGGACCCCAAGGGCATCCTCAACCCCTACAAGACGCTGCCCAGCCAG
  GCC
  
• Restriction Sites: Please inquire
• ACCN: BC036604
• ORF Size: 1566 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: BC036604.2, AAH36604.2
• RefSeq Size: 2570
• RefSeq ORF: 1566
• Locus ID: 728294
• Domains: FAD-oxidase_C, FAD_binding_4
• Gene Summary: This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. [provided by RefSeq, Jul 2008]