Synaptotagmin 14 (SYT14) (NM_153262) Human Untagged Clone

CAT#: SC313987

SYT14 (untagged)-Human synaptotagmin XIV (SYT14), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SYT14
• Synonyms: SCAR11; sytXIV
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_153262, the custom clone sequence may differ by one or more nucleotides
  ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAA
  GTATCTCCAGAGGCAGTTGGATTTTTGTCAGCTGTTGGGGTGTTTATTATCTTGATGCTG
  CTCCTTTTTCTCTATATTAATAAGAAGTTCTGTTTTGAAAATGTTGGCGGGTTTCCAGAT
  CTTGGTTCAGAATACAGTACAAGGAAGAATTCACAAGATAAAATTTATAATTCCTACATG
  GACAAAGATGAGCATGGTTCATCCTCTGAAAGTGAAGATGAAGCGCTGGGTAAATATCAT
  GAGGCCTTATCCAGAACACACAATTCCAGACTACCACTGGCAGATTCTAGACAAAGGAAC
  TATGCTTGGGAAACAAGGCAGAAATACAGTCCTCTATCGGCAGAGTATGATGGATACAGT
  AGTGAAGCATCAATAGATGAAGGAAACTGCATTCAGAGAATGAGAAGAACACCCCCGCTG
  GATGAATTGCAGCCACCACCATATCAGGATGACAGTGGTTCTCCCCATCTGTCATGTACA
  CCCTCAGAAATTGGGGACAGTAAATGTGAATTTTCCCACTGCAGCAACAGTCCAAGATGC
  TCATATAACAAGTGCCCAAGTGAAGGAAGCACAGGTCATGAAATAGAAAGTTTTCATAAT
  AAAGGATATGAAGAAGATGTTCCAAGTGACAGCACTGCAGTCCTGAGCCCTGAAGATATG
  TCAGCTCAAGGATCATCTTCGCAGCTTCCTAAACCTTTTGATCCTGAGCCAGAAGCTAAA
  TATGGCACACTGGATGTGACTTTTGACTATGACTCACAAGAACAGAAGCTTCTGGTAACA
  GTGACAGCTGTCACAGACATCCCAACATATAACAGGACAGGTGGCAACTCATGGCAAGTA
  CACCTTGTTCTTCTACCTATAAAGAAACAGAGAGCAAAAACCAGCATCCAGAGAGGACCA
  TGCCCTGTCTTCACAGAAACATTTAAATTTAATCATGTTGAATCTGAGATGATTGGAAAT
  TATGCAGTTCGGTTTAGACTGTATGGTGTACATCGCATGAAAAAAGAAAAGATTGTGGGG
  GAAAAGATTTTTTATTTAACAAAATTGAATCTTCAAGGGAAAATGTCATTGCCTGTGATA
  TTGGAACCTTCTTACAATCATTCTGGCTGTGACTCCCAAATGAGCGTGTCAGAAATGTCG
  TGTAGTGAAAGTACATCCTCATGTCAGTCTCTTGAACATGGCTCAGTTCCAGAAATTCTT
  ATTGGCCTGCTTTATAATGCCACAACTGGAAGACTATCAGCAGAAGTGATAAAAGGCAGC
  CACTTCAAAAATTTGGCAGCAAACAGACCACCCAATACATATGTTAAGTTAACTCTACTG
  AATTCCATGGGTCAAGAGATGTCCAAATGCAAGACATCCATCCGCAGAGGGCAGCCAAAT
  CCAGTATATAAGGAAACTTTTGTCTTTCAAGTGGCCCTATTTCAGCTTTCTGATGTGACA
  CTCATACTGTCTGTGTATAACAAACGCAGCATGAAAAGAGAAGAGATGATAGGCTGGATT
  TCTTTAGGTCTCAACAGCTCTGGAGAAGAAGAACTCAATCACTGGACTGAAATGAAAGAG
  TCAAAAGGACAGCAAGTATGTAGATGGCATGCGTTGCTAGAGTCA
  
• Restriction Sites: Please inquire
• ACCN: NM_153262
• ORF Size: 1668 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_153262.1, NP_694994.1
• RefSeq Size: 2960
• RefSeq ORF: 1668
• Locus ID: 255928
• Domains: C2
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (4) lacks two exons in the coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (4) is shorter and has a distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.