HPS4 (NM_152841) Human Untagged Clone

CAT#: SC314470

HPS4 (untagged)-Human Hermansky-Pudlak syndrome 4 (HPS4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HPS4
• Synonyms: BLOC3S2; LE
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_152841, the custom clone sequence may differ by one or more nucleotides
  ATGGCTCCACTCTGTTCTCTTGCCAGGTGGAATTATTTTTTTCTTTATGATGGTTCCAAG
  GTAAAGGAAGAAGGCGATCCAACAAGAGCTGGCATTTGTTACTTTTATCCTTCCCAGACC
  CTGCTAGACCAACAGGAGTTGCTTTGTGGACAGATTGCTGGAGTTGTCCGCTGTGTTTCT
  GACATTTCTGACTCTCCTCCTACTCTTGTTCGTCTGAGAAAACTGAAGTTTGCCATAAAA
  GTTGATGGAGATTACCTTTGGGTGCTGGGCTGTGCTGTGGAGCTCCCTGATGTCAGCTGC
  AAGCGGTTTCTGGATCAGCTAGTTGGATTCTTTAATTTTTACAATGGACCTGTTTCCCTA
  GCTTATGAGAACTGTTCTCAGGAAGAACTGAGCACGGAGTGGGACACCTTCATCGAGCAA
  ATTCTGAAAAACACCAGTGATCTGCATAAGATTTTCAATTCCCTCTGGAACTTGGACCAA
  ACTAAAGTGGAGCCCCTGTTGTTGCTGAAGGCAGCCCGCATTCTGCAGACCTGCCAGCGC
  TCGCCTCACATTCTCGCTGGCTGCATCCTCTATAAAGGACTGATTGTCAGCACCCAACTC
  CCGCCCTCCCTCACCGCCAAGGTCCTGCTTCACCGAACAGCACCTCAGGAGCAGAGACTC
  CCTACGGGAGAGGATGCCCCGCAGGAACATGGAGCGGCATTGCCCCCGAATGTCCAGATT
  ATCCCTGTTTTTGTGACCAAAGAGGAAGCCATTAGTCTCCACGAGTTCCCGGTGGAACAG
  ATGACAAGGTCTCTAGCATCTCCAGCAGGACTCCAGGATGGTTCAGCCCAGCACCATCCA
  AAGGGTGGGAGCACATCTGCCCTGAAAGAAAACGCCACTGGCCATGTGGAATCCATGGCC
  TGGACCACCCCAGATCCCACATCCCCTGACGAAGCTTGTCCAGATGGCAGGAAGGAGAAC
  GGATGCTTGTCTGGCCATGATCTGGAGAGCATCAGGCCCGCAGGACTGCACAACTCTGCC
  AGGGGTGAGGTTCTTGGCCTCAGCTCCTCCCTGGGGAAGGAACTAGTCTTTCTCCAAGAA
  GAACTCGACTTGTCTGAAATCCACATTCCAGAGGCTCAGGAAGTGGAAATGGCCTCAGGT
  CATTTTGCCTTCCTACATGTGCCTGTTCCAGATGGCAGGGCTCCTTACTGCAAGGCATCT
  CTCAGCGCCTCCAGCAGCCTGGAACCCACGCCTCCTGAGGACACAGCCATCAGCAGCTTG
  CGCCCTCCCTCTGCTCCTGAGATGCTGACCCAGCATGGAGCCCAAGAGCAGCTCGAAGAC
  CATCCTGGCCATAGCAGCCAAGCCCCCATTCCCAGAGCAGACCCTCTCCCCAGAAGGACC
  CGCAGGCCCTTGTTATTGCCTCGCTTAGATCCAGGACAGAGAGGAAACAAGCTTCCCACG
  GGGGAACAAGGCCTGGATGAGGATGTTGATGGGGTCTGTGAAAGCCACGCAGCCCCTGGT
  CTGGAATGCAGTTCAGGCTCAGCAAACTGTCAGGGTGCTGGCCCCTCTGCAGATGGAATC
  AGCTCCAGGCTGACACCAGCAGAGTCCTGCATGGGGCTCGTGAGGATGAATCTCTACACT
  CACTGCGTCAAAGGGCTGGTGCTGTCCCTGCTGGCTGAGGAGCCGCTGCTGGGAGACAGC
  GCAGCCATAGAGGAAGTGTACCACAGCAGCCTGGCTTCACTGAATGGGCTGGAAGTCCAC
  CTGAAAGAGACGCTGCCCAGGGATGAGGCAGCCTCCACGAGCAGCACCTACAACTTCACA
  CATTACGACCGCATTCAGAGCTTGCTGATGGCAAACCTGCCGCAGGTGGCCACCCCGCAG
  GATCGCCGCTTCCTCCAGGCCGTCAGCCTGATGCATAGCGAATTTGCCCAGCTGCCCGCG
  CTTTATGAAATGACTGTCAGAAATGCCTCCACGGCTGTGTACGCCTGTTGCAACCCCATC
  CAGGAGACATATTTCCAGCAGCTGGCACCTGCAGCACGGAGCTCCGGCTTCCCAAACCCT
  CAGGATGGCGCCTTCAGCCTCTCCGGCAAAGCAAAGCAGAAGCTGCTGAAGCACGGGGTG
  AACTTGCTC
  
• Restriction Sites: Please inquire
• ACCN: NM_152841
• ORF Size: 2112 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_152841.1, NP_690054.1
• RefSeq Size: 4069
• RefSeq ORF: 2112
• Locus ID: 89781
• Gene Summary: This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) is shorter and has a distinct N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.