NRG1 (AF009227) Human Untagged Clone

CAT#: SC314649

(untagged)-Human gamma-heregulin mRNA, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NRG1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AF009227, the custom clone sequence may differ by one or more nucleotides
  ATGGACGTGAAGGAGAGGAAGCCTTACCGCTCGCTGACCCGGCGCCGCGACGCCGAGCGC
  CGCTACACCAGCTCGTCCGCGGACAGCGAGGAGGGCAAAGCCCCGCAGAAATCGTACAGC
  TCCAGCGAGACCCTGAAGGCCTACGACCAGGACGCCCGCCTAGCCTATGGCAGCCGCGTC
  AAGGACATTGTGCCGCAGGAGGCCGAGGAATTCTGCCGCACAGGTGCCAACTTCACCCTG
  CGGGAGCTGGGGCTGGAAGAAGTAACGCCCCCTCACGGGACCCTGTACCGGACAGACATT
  GGCCTCCCCCACTGCGGCTACTCCATGGGGGCTGGCTCTGATGCCGACATGGAGGCTGAC
  ACGGTGCTGTCCCCTGAGCACCCCGTGCGTCTGTGGGGCCGGAGCACACGGTCAGGGCGC
  AGCTCCTGCCTGTCCAGCCGGGCCAATTCCAATCTCACACTCACCGACACCGAGCATGAA
  AACACTGAGACTGATCATCCGGGCGGCCTGCAGAACCACGCGCGGCTCCGGACGCCGCCG
  CCGCCGCTCTCGCACGCCCACACCCCCAACCAGCACCACGCGGCCTCCATTAACTCCCTG
  AACCGGGGCAACTTCACGCCGAGGAGCAACCCCAGCCCGGCCCCCACGGACCACTCGCTC
  TCCGGAGAGCCCCCTGCCGGCGGCGCCCAGGAGCCTGCCCACGCCCAGGAGAACTGGCTG
  CTCAACAGCAACATCCCCCTGGAGACCAGAAACCTAGGCAAGCAGCCATTCCTAGGGACA
  TTGCAGGACAACCTCATTGAGATGGACATTCTCGGCGCCTCCCGCCATGATGGGGCTTAC
  AGTGACGGGCACTTCCTCTTCAAGCCTGGAGGCACCTCCCCGCTCTTCTGCACCACATCA
  CCAGGGTACCCACTGACGTCCAGCACAGTGTACTCTCCTCCGCCCCGACCCCTGCCCCGC
  AGCACCTTCGCCCGGCCGGCCTTTAACCTCAAGAAGCCCTCCAAGTACTGTAACTGGAAG
  TGCGCAGCCCTGAGCGCCATCGTCATCTCAGCCACTCTGGTCATCCTGCTGGCATACTTT
  GTGGCCATGCACCTGTTTGGCCTAAACTGGCACCTGCAGCCGATGGAGGGGCAGATGTAT
  GAGATCACGGAGGACACAGCCAGCAGTTGGCCTGTGCCAACCGACGTCTCCCTATACCCC
  TCAGGGGGCACTGGCTTAGAGACCCCTGACAGGAAAGGCAAAGGAACCACAGAAGGAAAG
  CCCAGTAGTTTCTTTCCAGAGGACAGTTTCATAGATTCTGGAGAAATTGATGTGGGAAGG
  CGAGCTTCCCAGAAGATTCCTCCTGGCACTTTCTGGAGATCTCAAGTGTTCATAGACCAT
  CCTGTGCATCTGAAATTCAATGTGTCTCTGGGAAAGGCAGCCCTGGTTGGCATTTATGGC
  AGAAAAGGCCTCCCTCCTTCACATACACAGTTTGACTTTGTGGAGCTGCTGGATGGCAGG
  AGGCTCCTAACCCAGGAGGCGCGGAGCCTAGAGGGGACCCCGCGCCAGTCTCGGGGAACT
  GTGCCCCCCTCCAGCCATGAGACAGGCTTCATCCAGTATTTGGATTCAGGAATCTGGCAC
  TTGGCTTTTTACAATGACGGAAAGGAGTCAGAAGTGGTTTCCTTTCTCACCACTGCCATT
  GCCTTGCCTCCCCGATTGAAAGAGATGAAAAGCCAGGAATCGGCTGCAGGTTCCAAACTA
  GTCCTTCGGTGTGAAACCAGTTCTGAATACTCCTCTCTCAGATTCAAGTGGTTCAAGAAT
  GGGAATGAATTGAATCGAAAAAACAAACCACAAAATATCAAGATACAAAAAAAGCCAGGG
  AAGTCAGAACTTCGCATTAACAAAGCATCACTGGCTGATTCTGGAGAGTATATGTGCAAA
  GTGATCAGCAAATTAGGAAATGACAGTGCCTCTGCCAATATCACCATCGTGGAATCAAAC
  GAGATCATCACTGGTATGCCAGCCTCAACTGAAGGAGCATATGTGTCTTCAGAGTCTCCC
  ATTAGAATATCAGTATCCACAGAAGGAGCAAATACTTCTTCATCTACATCTACATCCACC
  ACTGGGACAAGCCATCTTGTAAAATGTGCGGAGAAGGAGAAAACTTTCTGTGTGAATGGA
  GGGGAGTGCTTCATGGTGAAAGACCTTTCAAACCCCTCGAGATACTTGTGCAAGTGCCCA
  AATGAGTTTACTGGTGATCGCTGCCAAAACTACGTAATGGCCAGCTTCTACAGTACGTCC
  ACTCCCTTTCTGTCTCTGCCTGAA
  
• Restriction Sites: Please inquire
• ACCN: AF009227
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: AF009227.1, AAC51756.1
• RefSeq Size: 3111 bp
• RefSeq ORF: 3111 bp
• Locus ID: 3084
• Cytogenetics: 8p12
• Domains: ig, IGc2, IG, EGF, EGF
• Protein Families: Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane
• Protein Pathways: ErbB signaling pathway
• Gene Summary: 'The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]'