PCDHA6 (NM_031848) Human Untagged Clone

CAT#: SC314737

PCDHA6 (untagged)-Human protocadherin alpha 6 (PCDHA6), transcript variant 2


  "NM_031848" in other vectors (4)

Reconstitution Protocol

USD 1,630.00

5 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PCDHA6
Synonyms CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_031848, the custom clone sequence may differ by one or more nucleotides
ATGGTGTTTACCCCGGAGGATAGATTGGGAAAGCAATGTCTGCTCCTCCCGCTTCTGCTC
CTCGCAGCCTGGAAGGTGGGGAGCGGCCAGCTCCACTACTCCGTACCCGAGGAGGCCAAA
CACGGCACCTTCGTGGGCCGGATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTG
CCGCGCCTGTTCAGGATGGCCTCCAAAGACCGCGAGGACCTTCTGGAGGTAAATCTGCAG
AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGGAGCTGTGCGGGCGGAGCGCG
GAGTGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGGAC
GTGGAGGTGAGGGACATTAACGACAACCCGCCCTTGTTCCCGGTAGAGGAACAAAGAGTG
CTGATTTACGAATCTAGGCTGCCAGATTCTGTGTTTCCACTGGAGGGCGCGTCCGATGCA
GATGTTGGCTCAAATTCCATCTTAACCTATAAACTCAGTTCTAGCGAATACTTCGGGCTA
GATGTGAAAATAAACAGTGATGACAATAAACAAATTGGGCTCTTATTAAAGAAATCCTTG
GACAGAGAGGAAGCTCCTGCACACAACTTATTCCTGACAGCCACAGATGGGGGCAAACCT
GAGCTCACAGGCACTGTTCAGCTGCTGGTCACAGTGCTGGATGTGAATGATAATGCTCCC
ACTTTCGAACAGTCTGAATACGAAGTAAGAATATTCGAAAATGCAGACAACGGAACAACA
GTTATCAGACTGAATGCTTCTGATCGGGATGAAGGAGCGAATGGGGCAATTTCATATTCT
TTTAATAGCCTTGTTGCAGCCATGGTTATTGACCACTTTAGCATAGATCGAAATACGGGA
GAAATAGTGATTCGGGGTAATTTGGATTTTGAACAAGAAAACTTATACAAAATCCTCATT
GACGCCACGGACAAAGGCCATCCTCCCATGGCGGGTCATTGCACCGTTTTAGTGAGAATT
TTGGATAAAAATGATAACGTCCCTGAGATAGCACTGACTTCCTTATCCTTGCCTGTACGT
GAAGACGCTCAATTTGGTACTGTCATCGCCCTAATTAGCGTGAACGACCTCGATTCAGGT
GCCAACGGGCAGGTGAACTGCTCGCTGACGCCTCACGTCCCTTTCAAGCTGGTGTCCACC
TTCAAGAATTACTACTCGTTGGTGCTGGACAGTGCCCTGGACCGCGAGAGCGTGTCGGCC
TATGAGTTGGTGGTAACCGCGCGGGACGGGGGCTCGCCTTCGCTGTGGGCCACCGCCAGC
TTGTCTGTGGAGGTGGCCGACATGAATGACAATGCTCCGGCGTTCGCGCAGCCCGAGTAC
ACAGTGTTCGTGAAGGAGAACAACCCGCCGGGCTGCCACATCTTCACGGTGTCTGCGCGA
GACGCGGACGCGCAGGAGAACGCGCTGGTGTCCTACTCGCTGGTGGAGCGGCGGGTGGGC
GAGCGCGCGTTGTCGAGCTACATTTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTG
CAGCCGCTGGACCACGAGGAGCTAGAGCTGCTGCAGTTTCAGGTGAGCGCGCGCGACGCG
GGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
AACGCGCCGGCGCTGCTGGCGCCTCGGGTGGGTGGTACTGGTGGTGCAGTGAGCGAGCTG
GTGCCGCGGTCACTGGGTGCAGGCCAAGTGGTGGCGAAGGTGCGCGCAGTTGACGCCGAC
TCAGGCTACAACGCGTGGCTTTCGTATGAGCTGCAGCCCCCGGCAAGCAGCGCTCGCTTC
CCGTTTCGCGTGGGGCTGTACACGGGCGAGATCAGCACCACTCGTGTCCTGGACGAAGCG
GACTCTCCGCGCCACCGGCTGCTGGTGCTGGTGAAAGACCACGGTGAGCCGGCGCTGACA
GCGACGGCCACGGTTCTGGTGTCGCTGGTGGAGAGTGGCCAGGCTCCAAAGGCGTCATCA
CGGGCGTCGGTGGGCGCCGCGGGCCCAGAGGCGGCGCTGGTGGATGTCAACGTGTACCTG
ATCATCGCCATCTGCGCGGTATCCAGCCTGCTGGTCCTCACGCTACTGCTGTACACAGCG
CTGCGGTGCTCGGCGCCACCCACCGAGGGCGCGTGCACGGCGGACAAGCCCACGCTGGTG
TGCTCCAGCGCAGTGGGGAGCTGGTCGTACTCGCAGCAGAGGCGGCAGAGGGTGTGCTCC
GGGGAGGGCCCACCCAAGATGGATCTCATGGCCTTTAGCCCCAGCCTTTCACCTTGTCCT
ATTATGATGGGTAAGGCGGAGAATCAGGATTTAAATGAAGATCATGATGCCAAAGTAAGT
GAATTTTCA
Restriction Sites Please inquire     
ACCN NM_031848
ORF Size 2412 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_031848.1, NP_114036.1
RefSeq Size 2439
RefSeq ORF 2412
Locus ID 56142
Protein Families Secreted Protein, Transmembrane
Gene Summary This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929.

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