PCDHA6 (NM_031848) Human Untagged Clone

CAT#: SC314737

PCDHA6 (untagged)-Human protocadherin alpha 6 (PCDHA6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA6
• Synonyms: CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031848, the custom clone sequence may differ by one or more nucleotides
  ATGGTGTTTACCCCGGAGGATAGATTGGGAAAGCAATGTCTGCTCCTCCCGCTTCTGCTC
  CTCGCAGCCTGGAAGGTGGGGAGCGGCCAGCTCCACTACTCCGTACCCGAGGAGGCCAAA
  CACGGCACCTTCGTGGGCCGGATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTG
  CCGCGCCTGTTCAGGATGGCCTCCAAAGACCGCGAGGACCTTCTGGAGGTAAATCTGCAG
  AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGGAGCTGTGCGGGCGGAGCGCG
  GAGTGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGGAC
  GTGGAGGTGAGGGACATTAACGACAACCCGCCCTTGTTCCCGGTAGAGGAACAAAGAGTG
  CTGATTTACGAATCTAGGCTGCCAGATTCTGTGTTTCCACTGGAGGGCGCGTCCGATGCA
  GATGTTGGCTCAAATTCCATCTTAACCTATAAACTCAGTTCTAGCGAATACTTCGGGCTA
  GATGTGAAAATAAACAGTGATGACAATAAACAAATTGGGCTCTTATTAAAGAAATCCTTG
  GACAGAGAGGAAGCTCCTGCACACAACTTATTCCTGACAGCCACAGATGGGGGCAAACCT
  GAGCTCACAGGCACTGTTCAGCTGCTGGTCACAGTGCTGGATGTGAATGATAATGCTCCC
  ACTTTCGAACAGTCTGAATACGAAGTAAGAATATTCGAAAATGCAGACAACGGAACAACA
  GTTATCAGACTGAATGCTTCTGATCGGGATGAAGGAGCGAATGGGGCAATTTCATATTCT
  TTTAATAGCCTTGTTGCAGCCATGGTTATTGACCACTTTAGCATAGATCGAAATACGGGA
  GAAATAGTGATTCGGGGTAATTTGGATTTTGAACAAGAAAACTTATACAAAATCCTCATT
  GACGCCACGGACAAAGGCCATCCTCCCATGGCGGGTCATTGCACCGTTTTAGTGAGAATT
  TTGGATAAAAATGATAACGTCCCTGAGATAGCACTGACTTCCTTATCCTTGCCTGTACGT
  GAAGACGCTCAATTTGGTACTGTCATCGCCCTAATTAGCGTGAACGACCTCGATTCAGGT
  GCCAACGGGCAGGTGAACTGCTCGCTGACGCCTCACGTCCCTTTCAAGCTGGTGTCCACC
  TTCAAGAATTACTACTCGTTGGTGCTGGACAGTGCCCTGGACCGCGAGAGCGTGTCGGCC
  TATGAGTTGGTGGTAACCGCGCGGGACGGGGGCTCGCCTTCGCTGTGGGCCACCGCCAGC
  TTGTCTGTGGAGGTGGCCGACATGAATGACAATGCTCCGGCGTTCGCGCAGCCCGAGTAC
  ACAGTGTTCGTGAAGGAGAACAACCCGCCGGGCTGCCACATCTTCACGGTGTCTGCGCGA
  GACGCGGACGCGCAGGAGAACGCGCTGGTGTCCTACTCGCTGGTGGAGCGGCGGGTGGGC
  GAGCGCGCGTTGTCGAGCTACATTTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTG
  CAGCCGCTGGACCACGAGGAGCTAGAGCTGCTGCAGTTTCAGGTGAGCGCGCGCGACGCG
  GGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
  AACGCGCCGGCGCTGCTGGCGCCTCGGGTGGGTGGTACTGGTGGTGCAGTGAGCGAGCTG
  GTGCCGCGGTCACTGGGTGCAGGCCAAGTGGTGGCGAAGGTGCGCGCAGTTGACGCCGAC
  TCAGGCTACAACGCGTGGCTTTCGTATGAGCTGCAGCCCCCGGCAAGCAGCGCTCGCTTC
  CCGTTTCGCGTGGGGCTGTACACGGGCGAGATCAGCACCACTCGTGTCCTGGACGAAGCG
  GACTCTCCGCGCCACCGGCTGCTGGTGCTGGTGAAAGACCACGGTGAGCCGGCGCTGACA
  GCGACGGCCACGGTTCTGGTGTCGCTGGTGGAGAGTGGCCAGGCTCCAAAGGCGTCATCA
  CGGGCGTCGGTGGGCGCCGCGGGCCCAGAGGCGGCGCTGGTGGATGTCAACGTGTACCTG
  ATCATCGCCATCTGCGCGGTATCCAGCCTGCTGGTCCTCACGCTACTGCTGTACACAGCG
  CTGCGGTGCTCGGCGCCACCCACCGAGGGCGCGTGCACGGCGGACAAGCCCACGCTGGTG
  TGCTCCAGCGCAGTGGGGAGCTGGTCGTACTCGCAGCAGAGGCGGCAGAGGGTGTGCTCC
  GGGGAGGGCCCACCCAAGATGGATCTCATGGCCTTTAGCCCCAGCCTTTCACCTTGTCCT
  ATTATGATGGGTAAGGCGGAGAATCAGGATTTAAATGAAGATCATGATGCCAAAGTAAGT
  GAATTTTCA
  
• Restriction Sites: Please inquire
• ACCN: NM_031848
• ORF Size: 2412 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031848.1, NP_114036.1
• RefSeq Size: 2439
• RefSeq ORF: 2412
• Locus ID: 56142
• Protein Families: Secreted Protein, Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929.