PCDHA2 (NM_031495) Human Untagged Clone

CAT#: SC314780

PCDHA2 (untagged)-Human protocadherin alpha 2 (PCDHA2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA2
• Synonyms: PCDH-ALPHA2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031495, the custom clone sequence may differ by one or more nucleotides
  ATGGCGTCTTCTATCAGAAGGGGCCGAGGGGCCTGGACACGGCTGCTCTCGCTTCTGCTC
  CTCGCAGCCTGGGAGGTGGGGAGCGGCCAGCTCCGCTACTCCGTCCCCGAGGAGGCCAAA
  CACGGCACCTTCGTGGGCCGCATCGCGCAGGACCTGGGGCTGGAGCTGGAGGAGCTGGTG
  CCGCGCCTGTTCCGGGTGGCGTCCAAAAGACACGGGGACCTTCTGGAGGTAAATCTGCAG
  AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGGGAGGAGCTGTGCGGGCGGAGCGCG
  GAATGTAGCATCCACGTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGGAA
  GTGGAGGTGAAGGACATTAACGACAACCCGCCAATATTTCCAATGACAGTAAAGACTATC
  CGGTTTCCCGAATCAAGGCTGCTTGATTCTCGGTTTCCTCTAGAGGGAGCATCTGATGCA
  GATATAGGAGTAAATGCTCTTCTCTCCTACAAGCTCAGCTCCAGTGAGTTTTTCTTCCTA
  GATATACAGGCAAATGATGAACTAAGCGAATCTTTGTCTCTCGTGCTGGGGAAATCGCTG
  GACAGAGAGGAAACTGCTGAGGTTAATTTGTTACTGGTGGCTACTGATGGGGGCAAACCT
  GAGCTCACGGGCACCGTTCAAATACTTATTAAGGTATTAGATGTAAATGACAATGAACCA
  ACTTTTGCCCAATCAGTTTACAAAGTAAAATTGTTAGAGAATACGGCAAATGGGACCTTA
  GTGGTTAAGTTAAACGCTTCTGATGCAGATGAAGGACCGAACAGCGAGATTGTGTATTCA
  CTCGGTAGTGATGTGTCCTCCACTATACAGACTAAGTTTACCATAGATCCCATCTCAGGG
  GAAATCAGAACTAAGGGAAAATTAGATTATGAAGAAGCAAAGTCCTACGAGATTCAGGTC
  ACTGCAACTGACAAAGGAACCCCTTCAATGTCAGGACATTGTAAAATTTCATTAAAACTT
  GTGGACATCAATGATAACACACCAGAAGTCTCAATAACGTCTCTCTCACTTCCCATCTCA
  GAGAACGCTTCCCTGGGCACTGTCATTGCTCTCATCACGGTGTCGGATCGCGACTCTGGT
  ACGAATGGACATGTCACCTGCTCCCTGACGCCCCACGTCCCTTTCAAGCTGGTGTCCACC
  TTCAAGAATTACTACTCGTTGGTGCTGGACAGCGCCCTGGACCGCGAGAGCGTGTCAGCC
  TATGAGCTGGTGGTGACCGCACGGGACGGGGGCTCGCCTTCACTGTGGGCCACCACCAGC
  GTGTCCATCGAGGTGGCCGACGTGAACGACAACGCGCCGGCGTTCGCACAGCCTGAGTAC
  ACAGTATTCGTGAAGGAGAACAACCCGCCGGGCTGCCACATCTTCACGGTGTCAGCGTGG
  GATGCGGACGCGCAGGAGAACGCGCTGGTGTCCTACTCGCTGGTGGAGCGGCGGGTGGGC
  GAGCGCGCGTTGTCGAGCTACGTTTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTG
  CAGCCGCTGGACCACGAGGAAGTGGAGCTGCTGCAGTTCCAGGTGAGCGCGCGGGATGCG
  GGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
  AACGCGCCGGCACTGTTGGCGCCTAGGGCTGGCACCGCTGCTGGCGCAGTGAGTGAGCTG
  GTGCCGTGGTCGGTGGGTGCAGGGCACGTGGTGGCGAAGGTGCGCGCAGTGGACGCTGAC
  TCAGGCTACAACGCGTGGCTTTCGTACGAGCTTCAGCTGGGTACTGGCAGCGCTCGCATC
  CCGTTCCGCGTGGGGCTATACACGGGTGAGATCAGCACGACACGTGCCCTAGACGAGGCT
  GACTCCCCTCGACACCGCCTACTCGTGCTGGTGAAGGACCACGGCGAACCAGCGTTGACA
  GCCACGGCCACCGTGTTAGTGTCGTTGGTGGAAAGTGGCCAGGCACCCAAGGCCTCGTCG
  CGGGCGTGGGTGGGCGCCGCGGGCTCAGAGGCTACGCTGGTGGATGTCAACGTGTACCTG
  ATCATCGCCATCTGCGCGGTATCCAGCCTGTTGGTGCTCACGGTGCTGCTGTACACTGCG
  CTGCGGTGCTCGGTGCCACCCACCGAGGGTGCGCGCGCGCCAGGAAAGCCCACGCTGGTG
  TGCTCCAGCGCCGTGGGGAGCTGGTCTTACTCGCAGCAGAGGCGGCAGAGGGTGTGCTCT
  GGGGAGGACCCCCCCAAGACGGACCTCATGGCCTTCAGCCCTAGCTTATCTCAAGGTCCA
  GACTCCGCAGAAGAGAAACAGCTCTCAGAATCAGAATACGTAGGAAAGGTGAGTCTTTTA
  CTTTTTCTTGCCAATTCTAAAATTGTTCTTTTTAAAAAATTCTATATGATTTCTACTAGT
  TATTTAGATTCA
  
• Restriction Sites: Please inquire
• ACCN: NM_031495
• ORF Size: 2475 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031495.1, NP_113683.1
• RefSeq Size: 2619
• RefSeq ORF: 2475
• Locus ID: 56146
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929.