PCDHA10 (NM_031859) Human Untagged Clone

CAT#: SC314806

PCDHA10 (untagged)-Human protocadherin alpha 10 (PCDHA10), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA10
• Synonyms: CNR8; CNRN8; CNRS8; CRNR8; PCDH-ALPHA10
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031859, the custom clone sequence may differ by one or more nucleotides
  ATGGTTTCCAGATGTAGCTGCCTGGGGGTCCAGTGTCTGCTGCTCTCGCTTCTTCTCCTC
  GCAGCCTGGGAGGTGGGGAGCGGCCAGCTCCACTACTCAGTCTACGAGGAGGCCAGACAC
  GGCACCTTCGTGGGCCGCATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTGCAG
  CGCCTGTTCCGGGTGGCGTCCAAAAGACACGGGGACCTTCTGGAGGTAAATCTGCAGAAT
  GGCATTTTGTTTGTGAATTCTCGGATTGACCGCGAGGAGCTGTGCGGGCGGAGCGTGGAG
  TGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGGACGTG
  GAAGTGAAGGACATTAACGACAACCCGCCCAGGTTCTCCGTAACAGAACAAAAGCTCTCA
  ATACCTGAATCCAGACTGCTTGACTCTCGATTTCCACTAGAAGGCGCATCTGATGCGGAT
  GTTGGAGAGAACGCATTGCTTACTTACAAACTCAGTCCAAATGAGTATTTTGTTCTTGAT
  ATTATAAACAAAAAAGACAAAGACAAATTCCCAGTGCTTGTTCTGCGGAAGCTGCTGGAT
  CGTGAAGAAAATCCTCAGCTAAAGTTGTTGTTGACAGCAACTGATGGAGGCAAACCTGAA
  TTTACCGGATCTGTTTCTCTGCTGATCCTGGTGTTAGATGCCAATGATAACGCCCCTATC
  TTTGACAGACCGGTTTATGAAGTTAAGATGTATGAAAATCAAGTGAACCAAACATTAGTA
  ATACGGCTCAACGCTTCTGATTCGGATGAAGGAATAAACAAGGAAATGATGTATTCATTT
  AGCTCTTTGGTCCCACCCACGATAAGAAGGAAATTTTGGATAAACGAAAGGACGGGAGAA
  ATAAAAGTAAATGATGCTATTGACTTTGAGGACAGTAACACTTATGAAATTCATGTAGAT
  GTTACAGATAAGGGAAACCCACCTATGGTTGGTCACTGCACGGTCCTAGTGGAACTACTG
  GATGAAAATGATAATTCACCTGAGGTGATTGTCACTTCTCTGTCTCTCCCAGTGAAAGAA
  GATGCTCAAGTGGGCACCGTCATTGCCCTAATCAGCGTTTCTGACCATGATTCAGGAGCC
  AACGGACAGGTCACCTGCTCTCTGACGCCTCACGTTCCGTTCAAGCTGGTGTCCACCTAC
  AAGAATTACTACTCATTGGTGCTGGACAGCGCTCTGGACCGCGAGAGGGTGTCGGCCTAT
  GAGCTGGTGGTGACCGCGCGGGACGGGGGCTCGCCTCCGCTGTGGGCCACGGCCAGCGTG
  TCTGTGGAGGTGGCCGACGTGAACGACAACGCGCCTGCGTTCGCGCAGTCCGAGTACACG
  GTGTTCGTGAAGGAGAACAACCCGCCAGGCTGCCACATCTTCACGGTGTCTGCGTGGGAC
  GCGGACGCGCAGGAGAACGCCCTGGTGTCCTACTCTCTGGTGGAGCGGCGGTTGGGCGAG
  CGCTCGCTGTCGAGCTACGTGTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTGCAG
  CCGCTGGACCACGAGGAGCTGGAGCTGCTACAGTTCCAGGTGAGCGCGCGCGATGGGGGC
  GTGCCGCCTCTGGGCAGCAACTTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGACAAC
  GCTCCCGCGCTGCTGGCGTCTCCCGCTGGCAGCGCGGGCGGTGCAGTCAGTGAGCTGGTG
  CTGCGGTCGGTGGTTGCGGGTCACGTGGTGGCTAAGGTGCGCGCAGTGGACGCTGACTCT
  GGATACAACGCGTGGCTGTCGTATGAATTGCAGTCGGCGGCGGTTGGTGCACGCATCCCG
  TTTCGCGTGGGGCTGTACACGGGCGAGATCAGTACGACGCGCGCTCTGGATGAGACTGAC
  TCGCCACGCCAGCGCCTACTGGTGCTGGTGAAGGACCATGGCGAGCCGTCGCTGACGGCC
  ACGGCCACTGTGCTTGTGTCGCTTGTGGAGGGCAGCCAGGCACCCAAGGCCTCGTCGCGG
  GCTTCAGTGGGCGTGGCGCCCGAGGTGGCCCTGGTGGATGTCAACGTGTACCTGATCATC
  GCCATCTGCGCGGTGTCCAGCTTGCTGGTGCTCACGCTGCTGCTGTACACTGCACTGAGG
  TGCTCGGCGGCGCCCACCGAGGGCGCATGTGGGCCGGTGAAGCCCACGCTGGTGTGCTCT
  AGCGCGGTGGGGAGCTGGTCTTACTCGCAGCAGAGGCGGCAGAGGGTGTGTTCTGGGGAG
  GGCCTGCCCAAGGCGGACCTCATGGCCTTCAGCCCCAGCCTTCCACCATGCCCAATGGTA
  GATGTGGACGGGGAAGATCAGTCTATTGGAGGGGACCACTCTAGGAAGGTGGGTTATTAC
  GTTTTCATTTTCCTTTTGTGCTTTATGAATAATATTTTCTCTTACCGCATTTTCTCAAAT
  ATGTATCAGAATATTTCATTTTTGTCTACATTCCATTTATGCTTGAATATTTCTAGTGAT
  ACCTTTGTAATA
  
• Restriction Sites: Please inquire
• ACCN: NM_031859
• ORF Size: 2535 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031859.1, NP_114065.1
• RefSeq Size: 2535
• RefSeq ORF: 2535
• Locus ID: 56139
• Domains: CA
• Protein Families: Secreted Protein
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2).