PCDH10 (NM_020815) Human Untagged Clone

CAT#: SC314883

PCDH10 (untagged)-Human protocadherin 10 (PCDH10), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDH10
• Synonyms: OL-PCDH; PCDH19
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020815, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATTGTGCTATTATTGTTTGCCTTGCTCTGGATGGTGGAAGGAGTCTTTTCCCAGCTTCACTACACGG
  TACAGGAGGAGCAGGAACATGGCACTTTCGTGGGGAATATCGCTGAAGATCTGGGTCTGGACATTACAAA
  ACTTTCGGCTCGCGGGTTTCAGACGGTGCCCAACTCAAGGACCCCTTACTTAGACCTCAACCTGGAGACA
  GGGGTGCTGTACGTGAACGAGAAAATAGACCGCGAACAAATCTGCAAACAGAGCCCCTCCTGTGTCCTGC
  ACCTGGAGGTCTTTCTGGAGAACCCCCTGGAGCTGTTCCAGGTGGAGATCGAGGTGCTGGACATTAATGA
  CAACCCCCCCTCTTTCCCGGAGCCAGACCTGACGGTGGAAATCTCTGAGAGCGCCACGCCAGGCACTCGC
  TTCCCCTTGGAGAGCGCATTCGACCCAGACGTGGGCACCAACTCCTTGCGCGACTACGAGATCACCCCCA
  ACAGCTACTTCTCCCTGGACGTGCAGACCCAGGGGGATGGCAACCGATTCGCTGAGCTGGTGCTGGAGAA
  GCCACTGGACCGAGAGCAGCAAGCGGTGCACCGCTACGTGCTGACCGCGGTGGACGGAGGAGGTGGGGGA
  GGAGTAGGAGAAGGAGGGGGAGGTGGCGGGGGAGCAGGCCTGCCCCCCCAGCAGCAGCGCACCGGCACGG
  CCCTACTCACCATCCGAGTGCTGGACTCCAATGACAATGTGCCCGCTTTCGACCAACCCGTCTACACTGT
  GTCCCTACCAGAGAACTCTCCCCCAGGCACTCTCGTGATCCAGCTCAACGCCACCGACCCGGACGAGGGC
  CAGAACGGTGAGGTCGTGTACTCCTTCAGCAGCCACATTTCGCCCCGGGCGCGGGAGCTTTTCGGACTCT
  CGCCGCGCACTGGCAGACTGGAGGTAAGCGGCGAGTTGGACTATGAAGAGAGCCCAGTGTACCAAGTGTA
  CGTGCAAGCCAAGGACCTGGGCCCCAACGCCGTGCCTGCGCACTGCAAGGTGCTAGTGCGAGTACTGGAT
  GCTAATGACAACGCGCCAGAGATCAGCTTCAGCACCGTGAAGGAAGCGGTGAGTGAGGGCGCGGCGCCCG
  GCACTGTGGTGGCCCTTTTCAGCGTGACTGACCGCGACTCAGAGGAGAATGGGCAGGTGCAGTGCGAGCT
  ACTGGGAGACGTGCCTTTCCGCCTCAAGTCTTCCTTTAAGAATTACTACACCATCGTTACCGAAGCCCCC
  CTGGACCGAGAGGCGGGGGACTCCTACACCCTGACTGTAGTGGCTCGGGACCGGGGCGAGCCTGCGCTCT
  CCACCAGTAAGTCGATCCAGGTACAAGTGTCGGATGTGAACGACAACGCGCCGCGTTTCAGCCAGCCGGT
  CTACGACGTGTATGTGACTGAAAACAACGTGCCTGGCGCCTACATCTACGCGGTGAGCGCCACCGACCGG
  GATGAGGGCGCCAACGCCCAGCTTGCCTACTCTATCCTCGAGTGCCAGATCCAGGGCATGAGCGTCTTCA
  CCTACGTTTCTATCAACTCTGAGAACGGCTACTTGTACGCCCTGCGCTCCTTCGACTATGAGCAGCTGAA
  GGACTTCAGTTTTCAGGTGGAAGCCCGGGACGCTGGCAGCCCCCAGGCGCTGGCTGGTAACGCCACTGTC
  AACATCCTCATAGTGGATCAAAATGACAACGCCCCTGCCATCGTGGCGCCTCTACCAGGGCGCAACGGGA
  CTCCAGCGCGTGAGGTGCTGCCCCGCTCGGCGGAGCCGGGTTACCTGCTCACCCGCGTGGCCGCCGTGGA
  CGCGGACGACGGCGAGAACGCCCGGCTCACTTACAGCATCGTGCGTGGCAACGAAATGAACCTCTTTCGC
  ATGGACTGGCGCACCGGGGAGCTGCGCACAGCACGCCGAGTCCCGGCCAAGCGCGACCCCCAGCGGCCTT
  ATGAGCTGGTGATCGAGGTGCGCGACCATGGGCAGCCGCCCCTTTCCTCCACCGCCACCCTGGTGGTTCA
  GCTGGTGGATGGCGCCGTGGAGCCCCAGGGCGGGGGCGGGAGCGGAGGCGGAGGGTCAGGAGAGCACCAG
  CGCCCCAGTCGCTCTGGCGGCGGGGAAACCTCGCTAGACCTCACCCTCATCCTCATCATCGCGTTGGGCT
  CGGTGTCCTTCATCTTCCTGCTGGCCATGATCGTGCTGGCCGTGCGTTGCCAAAAAGAGAAGAAGCTCAA
  CATCTATACTTGTCTGGCCAGCGATTGCTGCCTCTGCTGCTGCTGCTGCGGTGGCGGAGGTTCGACCTGC
  TGTGGCCGCCAAGCCCGGGCGCGCAAGAAGAAACTCAGCAAGTCAGACATCATGCTGGTGCAGAGCTCCA
  ATGTACCCAGTAACCCGGCCCAGGTGCCGATAGAGGAGTCCGGGGGCTTTGGCTCCCACCACCACAACCA
  GAATTACTGCTATCAGGTATGCCTGACCCCTGAGTCCGCCAAGACCGACCTGATGTTTCTTAAGCCCTGC
  AGCCCTTCGCGGAGTACGGACACTGAGCACAACCCCTGCGGGGCCATCGTCACCGGTTACACCGACCAGC
  AGCCTGATATCATCTCCAACGGAAGCATTTTGTCCAACGAGGTAAGGCTGAAGCGAAAGGACCACCATCT
  CTCATCTCCTCCATCAGAAAGCCTCCTCTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_020815
• ORF Size: 2691 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020815.2, NP_065866.1
• RefSeq Size: 4621
• RefSeq ORF: 2691
• Locus ID: 57575
• Domains: CA
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (2) is intronless, and its 3' terminal end extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2 which is shorter, and has a distinct C-terminus, compared to isoform 1.