Kinesin 5C (KIF5C) (NM_004522) Human Untagged Clone

CAT#: SC314991

KIF5C (untagged)-Human kinesin family member 5C (KIF5C)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KIF5C
• Synonyms: CDCBM2; KINN; NKHC; NKHC-2; NKHC2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004522, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGATCCAGCCGAATGCAGCATCAAAGTGATGTGCCGGTTCCGGCCCCTCAACGAAGCGGAGATCC
  TCCGCGGGGACAAATTCATCCCCAAATTTAAAGGCGATGAGACCGTGGTGATCGGGCAAGGGAAGCCATA
  TGTCTTCGACAGAGTGCTACCTCCCAACACGACCCAAGAGCAGGTTTACAATGCATGTGCGAAGCAAATT
  GTCAAAGATGTCCTTGAAGGTTATAACGGGACGATTTTTGCGTATGGGCAGACTTCATCAGGAAAAACCC
  ACACCATGGAGGGGAAGCTGCATGACCCCCAGCTCATGGGGATCATCCCACGAATTGCCCATGATATCTT
  TGACCATATCTACTCCATGGATGAGAACCTGGAGTTTCACATAAAGGTTTCCTATTTTGAGATCTACTTG
  GACAAAATAAGGGACTTACTTGATGTATCCAAGACCAACTTGGCTGTTCATGAAGATAAAAACAGAGTCC
  CGTATGTAAAGGGGTGCACTGAGCGGTTTGTGTCGAGCCCTGAGGAAGTCATGGATGTAATAGATGAAGG
  CAAAGCAAACCGACACGTGGCTGTGACAAACATGAATGAACACAGCTCTAGAAGTCACAGTATCTTCCTG
  ATAAATATTAAACAAGAGAATGTAGAGACTGAAAAAAAACTCAGTGGGAAACTTTATTTGGTTGATTTGG
  CTGGGAGCGAAAAGGTCAGCAAAACTGGTGCCGAGGGAGCTGTTCTTGACGAAGCTAAAAATATCAATAA
  GTCTTTGTCTGCTCTTGGAAATGTGATCTCTGCTTTGGCAGAAGGGACAAAAACACATGTGCCATACCGG
  GACAGCAAGATGACTCGGATTCTTCAGGACTCTTTGGGTGGGAACTGCAGAACCACCATCGTCATTTGCT
  GTTCTCCTTCTGTCTTCAATGAGGCTGAGACCAAGTCCACACTGATGTTCGGACAGAGAGCTAAGACCAT
  CAAGAATACAGTCTCTGTGAACCTAGAACTGACAGCAGAAGAATGGAAGAAGAAATATGAAAAAGAGAAA
  GAGAAAAACAAGACTTTGAAGAATGTTATCCAGCATCTGGAGATGGAGCTAAACAGGTGGAGGAATGGAG
  AAGCTGTGCCTGAGGATGAACAGATCAGTGCCAAGGACCAGAAGAACCTGGAGCCTTGTGATAACACCCC
  CATCATAGACAATATTGCTCCTGTTGTTGCTGGCATCTCTACAGAGGAGAAAGAGAAGTACGATGAGGAG
  ATCTCCAGTCTCTACAGACAACTGGATGACAAGGATGATGAAATTAACCAGCAGAGCCAGCTGGCTGAAA
  AGCTGAAGCAACAGATGTTGGATCAGGATGAGCTTTTAGCTTCCACAAGAAGAGACTATGAGAAGATACA
  GGAGGAGCTGACACGTCTCCAGATTGAAAATGAGGCAGCCAAGGATGAGGTGAAAGAAGTTCTCCAGGCC
  CTGGAGGAGCTGGCTGTCAATTATGACCAGAAATCACAGGAAGTGGAGGATAAGACCCGGGCCAATGAGC
  AGCTGACAGACGAGCTGGCCCAGAAAACGACTACATTGACAACCACACAGAGAGAGCTGAGCCAGCTACA
  AGAGCTTAGCAACCACCAGAAGAAAAGGGCAACTGAGATCCTGAATTTGCTGTTGAAAGATCTGGGGGAG
  ATAGGTGGAATTATTGGCACCAATGATGTGAAAACTTTGGCAGATGTGAATGGAGTCATTGAGGAGGAGT
  TTACCATGGCCCGCCTGTACATCAGCAAGATGAAGTCAGAGGTCAAGTCCCTGGTGAACCGCAGCAAACA
  GCTCGAGAGCGCCCAGATGGACTCCAACAGGAAGATGAATGCCAGCGAGCGGGAGCTGGCAGCCTGCCAG
  CTGCTCATCTCCCAGCACGAAGCCAAGATCAAGTCTCTGACAGACTACATGCAGAACATGGAACAGAAGA
  GGAGGCAGCTAGAAGAGTCCCAGGACTCGCTCAGCGAAGAGCTGGCAAAGCTCCGAGCCCAGGAAAAAAT
  GCACGAAGTCAGCTTCCAGGATAAGGAGAAGGAACATCTGACGCGGTTGCAGGATGCTGAAGAAATGAAG
  AAGGCGCTGGAGCAGCAGATGGAGAGCCACCGGGAAGCTCACCAGAAGCAGCTGTCCAGACTCCGAGACG
  AAATTGAGGAGAAGCAGAAAATCATTGATGAGATTCGGGATTTGAATCAGAAACTGCAACTGGAACAGGA
  GAAGCTTAGTTCTGATTATAACAAGCTGAAAATAGAGGACCAAGAGAGAGAAATGAAGCTGGAAAAGCTC
  TTATTGCTCAACGATAAAAGGGAACAAGCCAGAGAAGACCTCAAAGGGCTGGAGGAGACAGTGTCTAGAG
  AATTGCAGACACTGCACAACCTTCGGAAACTCTTTGTCCAGGATCTGACCACCCGAGTTAAAAAAAGTGT
  GGAGTTGGACAACGATGATGGAGGGGGCAGTGCTGCCCAGAAGCAGAAAATTTCCTTCTTGGAGAATAAC
  CTGGAGCAGCTCACCAAAGTTCACAAGCAGCTGGTCCGGGACAACGCAGACCTGCGCTGTGAACTGCCCA
  AGCTGGAGAAGCGGCTGCGTGCCACGGCGGAGCGCGTCAAGGCTCTGGAGAGCGCGCTGAAGGAGGCCAA
  GGAGAACGCCATGCGGGACCGTAAGCGCTACCAGCAGGAGGTGGATCGTATCAAGGAGGCCGTGCGGGCC
  AAGAACATGGCCAGAAGGGCCCATTCAGCCCAGATCGCCAAGCCCATCCGCCCCGGACACTACCCGGCCT
  CATCTCCAACGGCCGTCCATGCCATTCGAGGGGGAGGAGGCAGCTCTTCAAATTCCACTCACTACCAGAA
  ATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_004522
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004522.2, NP_004513.1
• RefSeq Size: 6958 bp
• RefSeq ORF: 2874 bp
• Locus ID: 3800
• Cytogenetics: 2q23.1-q23.2
• Domains: kinesin
• Protein Families: Druggable Genome
• Gene Summary: 'The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Jul 2015]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the supported protein.