RTN3 (NM_201428) Human Untagged Clone
CAT#: SC315070
RTN3 (untagged)-Human reticulon 3 (RTN3), transcript variant 2
"NM_201428" in other vectors (4)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | RTN3 |
Synonyms | ASYIP; HAP; NSPL2; NSPLII; RTN3-A1 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_201428, the custom clone sequence may differ by one or more nucleotides
ATGGCGGAGCCGTCGGCGGCCACTCAGTCCCATTCCATCTCCTCGTCGTCCTTCGGAGCC GAGCCGTCCGCGCCCGGCGGCGGCGGGAGCCCAGGAGCCTGCCCCGCCCTGGGGACGAAG AGCTGCAGCTCCTCCTGTGCGGAGGGATTGAGCTCTCTTTGCTCTGATGAGCCATCTTCA GAAATTATGACTTCTTCCTTTCTTTCATCTTCTGAAATACATAACACTGGCCTTACAATA CTACATGGAGAAAAAAGCCATGTGTTAGGGAGCCAGCCTATTTTAGCCAAAGAAGGAAAA GACCACTTGGATCTTCTAGATATGAAAAAGATGGAAAAGCCTCAGGGGACCAGCAACAAC GTATCAGACTCTTCAGTTTCTCTTGCAGCAGGAGTTCATTGTGACCGTCCTTCTATTCCA GCCAGTTTCCCAGAGCATCCTGCTTTTCTCTCAAAGAAAATTGGTCAAGTGGAAGAGCAA ATAGATAAAGAGACCAAGAACCCAAATGGGGTATCAAGTAGGGAGGCTAAAACTGCATTG GATGCTGATGACAGATTCACTTTGCTGACAGCCCAGAAACCACCTACTGAGTACTCTAAG GTAGAAGGCATTTATACATATTCTTTGTCTCCATCCAAAGTTTCAGGAGATGATGTTATT GAAAAGGATTCCCCTGAATCACCATTTGAAGTAATTATTGACAAAGCAGCATTTGACAAA GAATTTAAAGACTCATATAAGGAGAGCACAGATGATTTTGGTAGCTGGTCTGTGCACACT GATAAAGAATCATCCGAAGACATTTCAGAGACTAATGACAAGCTTTTTCCACTGAGAAAT AAAGAGGCAGGACGTTACCCAATGTCTGCATTGCTCAGTAGGCAGTTTTCACACACAAAT GCAGCACTGGAAGAGGTGTCCAGATGCGTGAATGATATGCATAACTTTACTAACGAAATA CTGACTTGGGATCTGGTTCCCCAAGTGAAACAACAGACCGATAAATCTTCTGACTGCATC ACAAAAACTACAGGACTTGACATGAGTGAATATAATTCAGAAATTCCAGTTGTAAATCTT AAAACTAGCACTCATCAGAAAACTCCTGTATGTTCTATTGATGGGAGCACTCCCATCACT AAATCAACAGGTGATTGGGCAGAAGCATCTCTCCAGCAAGAAAATGCTATTACTGGAAAA CCTGTACCTGACTCTTTGAATTCCACAAAAGAATTCAGTATCAAAGGTGTGCAAGGCAAT ATGCAGAAACAGGATGACACACTTGCAGAATTACCTGGATCTCCACCTGAGAAATGTGAC TCTTTGGGTTCTGGAGTGGCCACAGTGAAAGTGGTTTTACCTGATGACCACCTGAAAGAT GAAATGGACTGGCAGAGCTCTGCATTGGGAGAAATCACAGAAGCTGATAGTTCTGGTGAG TCTGATGACACAGTAATAGAGGACATCACAGCAGATACATCATTTGAAAATAACAAAATT CAGGCTGAAAAACCTGTTTCCATTCCAAGTGCTGTTGTAAAAACAGGTGAAAGAGAAATC AAAGAGATTCCCAGTTGTGAGAGAGAAGAAAAAACATCTAAAAACTTTGAAGAATTGGTC AGTGACTCTGAGCTGCATCAAGATCAGCCTGATATTCTTGGAAGGAGTCCAGCTAGTGAG GCAGCATGTTCAAAAGTACCCGATACGAATGTCTCCTTAGAAGATGTGAGTGAAGTTGCT CCTGAAAAGCCTATTACTACTGAGAACCCCAAACTTCCTTCAACAGTGTCTCCAAATGTT TTTAATGAGACAGAATTCTCATTAAATGTGACAACATCTGCCTATTTGGAGTCATTACAT GGGAAAAATGTTAAACATATAGATGATTCCTCCCCAGAGGACCTGATAGCAGCCTTTACA GAAACCAGAGATAAAGGAATAGTAGATAGTGAAAGAAATGCTTTTAAAGCAATATCAGAG AAGATGACAGACTTTAAAACAACTCCTCCTGTAGAAGTCTTACATGAAAATGAGTCCGGT GGTTCTGAAATTAAAGACATTGGAAGCAAATACAGTGAACAAAGCAAAGAAACAAATGGA AGTGAGCCTCTAGGTGTTTTCCCTACCCAAGGTACTCCAGTAGCATCTCTTGACTTAGAA CAAGAACAGCTCACAATTAAGGCTCTTAAAGAATTAGGTGAAAGACAGGTTGAGAAGTCA ACTTCTGCACAGCGTGACGCAGAATTGCCTTCTGAAGAAGTACTGAAGCAAACTTTCACA TTTGCTCCAGAATCTTGGCCACAGAGATCATATGACATCCTAGAACGTAATGTCAAGAAT GGATCTGATCTTGGGATTTCCCAGAAGCCCATCACTATCAGAGAAACTACTAGGGTAGAT GCTGTTTCCAGCCTTAGCAAGACTGAATTGGTAAAAAAGCATGTCCTAGCAAGACTTCTG ACAGACTTCTCAGTGCACGATCTGATTTTCTGGAGAGATGTGAAGAAGACTGGGTTTGTC TTTGGCACCACGCTGATCATGCTGCTTTCCCTGGCAGCTTTCAGTGTCATCAGTGTGGTT TCTTACCTCATCCTGGCTCTTCTCTCTGTCACCATCAGCTTCAGGATCTACAAGTCCGTC ATCCAAGCTGTACAGAAGTCAGAAGAAGGCCATCCATTCAAAGCCTACCTGGACGTAGAC ATTACTCTGTCCTCAGAAGCTTTCCATAATTACATGAATGCTGCCATGGTGCACATCAAC AGGGCCCTGAAACTCATTATTCGTCTCTTTCTGGTAGAAGATCTGGTTGACTCCTTGAAG CTGGCTGTCTTCATGTGGCTGATGACCTATGTTGGTGCTGTTTTTAACGGAATCACCCTT CTAATTCTTGCTGAACTGCTCATTTTCAGTGTCCCGATTGTCTATGAGAAGTACAAGACC CAGATTGATCACTATGTTGGCATCGCCCGAGATCAGACCAAGTCAATTGTTGAAAAGATC CAAGCAAAACTCCCTGGAATCGCCAAAAAAAAGGCAGAA |
Restriction Sites | Please inquire |
ACCN | NM_201428 |
ORF Size | 3042 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Reference Data | |
RefSeq | NM_201428.1, NP_958831.1 |
RefSeq Size | 4942 |
RefSeq ORF | 3042 |
Locus ID | 10313 |
Protein Families | Transmembrane |
Gene Summary | This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012] Transcript Variant: This variant (2) includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (b) is longer than isoform a. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC220992 | RTN3 (Myc-DDK-tagged)-Human reticulon 3 (RTN3), transcript variant 2 |
USD 1,060.00 |
|
RG220992 | RTN3 (GFP-tagged) - Human reticulon 3 (RTN3), transcript variant 2 |
USD 1,170.00 |
|
RC220992L3 | Lenti-ORF clone of RTN3 (Myc-DDK-tagged)-Human reticulon 3 (RTN3), transcript variant 2 |
USD 1,260.00 |
|
RC220992L4 | Lenti-ORF clone of RTN3 (mGFP-tagged)-Human reticulon 3 (RTN3), transcript variant 2 |
USD 1,260.00 |
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