SEC31A (NM_016211) Human Untagged Clone

CAT#: SC315243

SEC31A (untagged)-Human SEC31 homolog A (S. cerevisiae) (SEC31A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEC31A
• Synonyms: ABP125; ABP130; HSPC275; HSPC334; SEC31L1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_016211, the custom clone sequence may differ by one or more nucleotides
  ATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCAC
  CCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAAT
  GCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGT
  GCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGAT
  TCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTC
  TATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAG
  CATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCT
  GGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACA
  CCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTT
  CAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAA
  AATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCA
  TGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTG
  ATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCC
  AGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGA
  AAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCC
  ACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCA
  GCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGAAGCACAGATGGT
  TTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGC
  ACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTG
  CTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTT
  GGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAG
  CAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGC
  CGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAA
  AAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAAC
  TTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTA
  GGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGA
  ACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACG
  GGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATT
  ATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCA
  AAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAG
  ATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTAT
  GCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAA
  GGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAG
  AAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGAT
  CTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACT
  AGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCT
  CAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATC
  ATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCA
  CCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGC
  CACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCA
  CCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACA
  TCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCCTTATCAACCA
  GCCCAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAATGTATCGACCTCAGCAGCCTGTT
  GCTCCTCCTACTTCAAACGCTTACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTAT
  ACTGGGCAGTCTCAGCTGTACGCAGCACAGCACCAGGCCTCTTCACCTACCTCCAGCCCT
  GCTACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCATCCTTCCAGCATGGCGGACCAGGA
  GCTCCACCATCATCTTCAGCTTATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCT
  GCCAGTGAGCTGCCTGCGTCCCAAAGAACAGGTCCTCAGAATGGTTGGAATGACCCTCCA
  GCTTTGAACAGAGTACCCAAAAAGAAGAAGATGCCTGAAAACTTCATGCCTCCTGTTCCC
  ATCACATCACCAATCATGAACCCGTTGGGTGACCCCCAGTCACAAATGCTGCAGCAACAG
  CCTTCAGCTCCAGTACCACTGTCAAGCCAGTCTTCATTCCCACAGCCACATCTTCCAGGT
  GGCCAGCCCTTCCATGGCGTACAGCAACCTCTTGGTCAAACAGGCATGCCACCATCTTTT
  TCAAAGCCCAATATTGAAGGTGCCCCAGGGGCTCCTATTGGAAATACCTTCCAGCATGTG
  CAGTCTTTGCCAACAAAAAAAATTACCAAGAAACCTATTCCAGATGAGCACCTCATTCTA
  AAGACCACATTTGAGGATCTTATTCAGCGCTGCCTTTCTTCAGCAACAGACCCTCAAACC
  AAGAGGAAGCTAGATGATGCCAGCAAACGTTTGGAGTTTCTGTATGATAAACTTAGGGAA
  CAGACACTTTCACCAACAATCACCAGTGGTTTACACAACATTGCAAGGAGCATTGAAACT
  CGAAACTACTCAGAAGGATTGACCATGCATACCCACATAGTTAGCACCAGCAACTTCAGT
  GAGACCTCTGCTTTCATGCCAGTTCTCAAAGTTGTTCTCACCCAGGCCAATAAGCTGGGT
  GTC
  
• Restriction Sites: Please inquire
• ACCN: NM_016211
• ORF Size: 3546 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016211.2, NP_057295.2
• RefSeq Size: 4124
• RefSeq ORF: 3546
• Locus ID: 22872
• Domains: WD40
• Gene Summary: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (2) lacks two consecutive alternate in-frame exons in the central coding region, compared to variant 5. The encoded isoform (2) has the same N- and C-termini, but is shorter than isoform 1.