AATK (NM_001080395) Human Untagged Clone

CAT#: SC315882

AATK (untagged)-Human apoptosis-associated tyrosine kinase (AATK)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AATK
• Synonyms: AATYK; AATYK1; LMR1; LMTK1; p35BP; PPP1R77
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001080395 edited
  ATGACGCAGAATGGGCCAAGGAGCTGGCTCTGCCCACCTGTCCCGCTGGCCTGGCAGGTG
  ACGGTGCTGGATGTGGCCTTTTTGCCTTTTCTAAAGGCCACATTTTCCAGCCCATTCAAC
  CTTCCAGAGCCCTCTGAAGTGGCCACAGGCCCCATCAACCAGACCCGGCTGGCCCCCGGG
  CAGCAGGCTCTTAAGGAGTTCTGGGAGCTCCGGAGGTGGTGTGGCCACCAGGTGAAGGTC
  CAAGGCTGCTGGGGCAGATGGCGGTGGCAGGAGTTTGAGAATGCGGAGGGGGACGAGTAC
  GCAGCCGACCTGGCGCAGGGCTCCCCGGCCACGGCAGCACAGAACGGGCCCGACGTGTAC
  GTCCTGCCACTCACGGAGGTCTCCTTGCCCATGGCCAAGCAGCCTGGGCGCTCAGTGCAG
  CTCCTCAAGTCCACAGACGTGGGCCGGCACAGCCTCCTGTACCTGAAGGAAATCGGCCGT
  GGCTGGTTCGGGAAGGTGTTCCTGGGGGAGGTGAACTCTGGCATCAGCAGTGCCCAGGTG
  GTGGTGAAGGAGCTGCAGGCTAGTGCCAGCGTGCAGGAGCAGATGCAGTTCCTGGAGGAG
  GTGCAGCCCTACAGGGCCCTGAAGCACAGCAACCTGCTCCAGTGCCTGGCCCAGTGCGCC
  GAGGTGACGCCCTACCTGCTGGTGATGGAGTTCTGCCCACTGGGGGACCTCAAGGGCTAC
  CTGCGGAGCTGCCGGGTGGCGGAGTCCATGGCTCCCGACCCCCGGACCCTGCAGCGCATG
  GCCTGTGAGGTGGCCTGTGGCGTCCTGCACCTTCATCGCAACAATTTCGTGCACAGCGAC
  CTGGCCCTGCGGAACTGCCTGCTCACGGCTGACCTGACGGTGAAGATTGGTGACTATGGC
  CTGGCTCACTGCAAGTACAGAGAGGACTACTTCGTGACTGCCGACCAGCTGTGGGTGCCT
  CTGCGCTGGATCGCGCCAGAGCTGGTGGACGAGGTGCATAGCAACCTGCTCGTCGTGGAC
  CAGACCAAGAGCGGGAATGTGTGGTCCCTGGGCGTGACCATCTGGGAGCTCTTTGAGCTG
  GGCACGCAGCCCTATCCCCAGCACTCGGACCAGCAGGTGCTGGCGTACACGGTCCGGGAG
  CAGCAGCTCAAGCTGCCCAAGCCCCAGCTGCAGCTGACCCTGTCGGACCGCTGGTACGAG
  GTGATGCAGTTCTGCTGGCTGCAGCCCGAGCAGCGGCCCACAGCCGAGGAGGTGCACCTG
  CTGCTGTCCTACCTGTGTGCCAAGGGCGCCACCGAAGCAGAGGAGGAGTTTGAACGGCGC
  TGGCGCTCTCTGCGGCCCGGCGGGGGCGGCGTGGGGCCCGGGCCCGGTGCGGCGGGGCCC
  ATGCTGGGCGGCGTGGTGGAGCTCGCCGCTGCCTCGTCCTTCCCGCTGCTGGAGCAGTTC
  GCGGGCGACGGCTTCCACGCGGACGGCGACGACGTGCTGACGGTGACCGAGACCAGCCGA
  GGCCTCAATTTTGAGTACAAGTGGGAGGCGGGCCGCGGCGCGGAGGCCTTCCCGGCCACG
  CTGAGCCCTGGCCGCACCGCACGCCTCCAGGAGCTGTGCGCCCCCGACGGCGCGCCCCCG
  GGCGTGGTTCCGGTGCTCAGCGCGCACAGCCCGTCGCTGGGCAGCGAGTACTTCATCCGC
  CTAGAGGAGGCCGCACCCGCCGCCGGCCACGACCCTGACTGCGCCGGCTGCGCCCCCAGT
  CCACCTGCCACCGCGGACCAGGACGACGACTCTGACGGCAGCACCGCCGCCTCGCTGGCC
  ATGGAGCCGCTGCTGGGCCACGGGCCACCCGTCGACGTCCCCTGGGGCCGCGGCGACCAC
  TACCCTCGCAGAAGCTTGGCGCGGGACCCGCTCTGCCCCTCACGCTCTCCCTCGCCCTCG
  GCGGGGCCCCTGAGTCTGGCGGAGGGAGGAGCGGAGGATGCAGACTGGGGCGTGGCCGCC
  TTCTGTCCTGCCTTCTTCGAGGACCCACTGGGCACGTCCCCTTTGGGGAGCTCAGGGGCG
  CCCCCGCTGCCGCTGACTGGCGAGGATGAGCTAGAGGAGGTGGGAGCGCGGAGGGCCGCC
  CAGCGCGGGCACTGGCGCTCCAACGTGTCAGCCAACAACAACAGCGGCAGCCGCTGTCCA
  GAGTCCTGGGACCCCGTCTCTGCGGGCGGCCACGCTGAGGGCTGCCCCAGTCCAAAGCAG
  ACCCCACGGGCCTCCCCCGAGCCGGGGTACCCTGGAGAGCCTCTGCTTGGGCTCCAGGCA
  GCCTCTGCCCAGGAGCCAGGCTGCTGCCCCGGCCTCCCTCATCTATGCTCTGCCCAGGGC
  CTGGCACCTGCTCCCTGCCTGGTTACACCCTCCTGGACAGAGACAGCCAGTAGTGGGGGT
  GACCACCCGCAGGCAGAGCCCAAGCTTGCCACGGAGGCTGAGGGCACTACCGGACCCCGC
  CTGCCCCTTCCTTCCGTCCCCTCCCCATCCCAGGAGGGAGCCCCACTTCCCTCGGAGGAG
  GCCAGTGCCCCCGACGCCCCTGATGCCCTGCCTGACTCTCCCACGCCTGCTACTGGTGGC
  GAGGTGTCTGCCATCAAGCTGGCTTCTGCCCTGAATGGCAGCAGCAGCTCTCCCGAGGTG
  GAGGCACCCAGCAGTGAGGATGAGGACACGGCCGAGGCCACCTCAGGCATCTTCACCGAC
  ACGTCCAGCGACGGCCTGCAGGCCAGGAGGCCGGATGTGGTGCCAGCCTTCCGCTCTCTG
  CAGAAGCAGGTGGGGACCCCCGACTCCCTGGACTCCCTGGACATCCCGTCCTCAGCCAGT
  GATGGTGGCTATGAGGTCTTCAGCCCGTCGGCCACTGGCCCCTCTGGAGGGCAGCCGCGA
  GCGCTGGACAGTGGCTATGACACCGAGAACTATGAGTCCCCTGAGTTTGTGCTCAAGGAG
  GCGCAGGAAGGGTGTGAGCCCCAGGCCTTTGCGGAGCTGGCCTCAGAGGGTGAGGGCCCC
  GGGCCCGAGACACGGCTCTCCACCTCCCTCAGTGGCCTCAACGAGAAGAATCCCTACCGA
  GACTCTGCCTACTTCTCAGACCTCGAGGCTGAGGCCGAGGCCACCTCAGGCCCAGAGAAG
  AAGTGCGGCGGGGACCGAGCCCCCGGGCCAGAGCTGGGCCTGCCGAGCACTGGGCAGCCG
  TCTGAGCAGGTCTGTCTCAGGCCTGGGGTTTCCGGGGAGGCACAAGGCTCTGGCCCCGGG
  GAGGTGCTGCCCCCACTGCTGCAGCTTGAAGGGTCCTCCCCAGAGCCCAGCACCTGCCCC
  TCGGGCCTGGTCCCAGAGCCTCCGGAGCCCCAAGGCCCAGCCAAGGTGCGGCCTGGGCCC
  AGCCCCAGCTGCTCCCAGTTTTTCCTGCTGACCCCGGTTCCGCTGAGATCAGAAGGCAAC
  AGCTCTGAGTTCCAGGGGCCCCCAGGACTGTTGTCAGGGCCGGCCCCACAAAAGCGGATG
  GGGGGCCCAGGCACCCCCAGAGCCCCACTCCGCCTGGCTCTGCCCGGCCTCCCTGCGGCC
  TTGGAGGGCCGGCCGGAGGAGGAGGAGGAGGACAGTGAGGACAGCGACGAGTCTGACGAG
  GAGCTCCGCTGCTACAGCGTCCAGGAGCCTAGCGAGGACAGCGAAGAGGAGGCGCCGGCG
  GTGCCCGTGGTGGTGGCTGAGAGCCAGAGCGCGCGCAACCTGCGCAGCCTGCTCAAGATG
  CCCAGCCTGCTGTCCGAGACCTTCTGCGAGGACCTGGAACGCAAGAAGAAGGCCGTGTCC
  TTCTTCGACGACGTCACCGTCTACCTCTTTGACCAGGAAAGCCCCACCCGGGAGCTCGGG
  GAGCCCTTCCCGGGCGCCAAGGAATCGCCCCCTACGTCCCTTAGGGGGAGCCCCGGCTCT
  CCCAGCGCCCCCAACCGGCCGCAGCAGGCTGATGGCTCCCCAAATGGCTCCACAGCGGAA
  GAGGGTGGTGGGTTCGCGTGGGACGACGACTTCCCGCTGATGACGGCCAAGGCAGCCTTC
  GCCATGGCCCTAGACCCGGCCGCACCCGCCCCGGCTGCGCCCACGCCCACGCCCGCTCCC
  TTCTCGCGCTTCACGGTGTCGCCCGCGCCCACGTCCCGCTTCTCCATCACGCACGTGTCT
  GACTCGGACGCCGAGTCCAAGAGAGGACCTGAAGCTGGTGCCGGGGGTGAGAGTAAAGAG
  GCTTGAGACCTGGGCAGCTCCTGCCCCTCAAGGCTGGCGTCACCGGAGCCCCTGCCAGGC
  AGCAGCGAGGATGGTGACCGAGAAGGTGGGGACCACGTCCTGGTGGCTGTTGGCAGCAGA
  TTCAGGTGCCTCTGCCCCACGCGGTGTCCTGGAGAAGCCCGTGGGATGAGAGGCCCTGGA
  TGGTAGATCGGCCATGCTCCGCCCCAGAGGCAGAATTCGTCTGGGCTTTTAGGCTTGCTG
  CTAGCCCCTGGGGGCGCCTGGAGCCACAGTGGGTGTCTGTACACACATACACACTCAAAA
  GGGGCCAGTGCCCCTGGGCACGGCGGCCCCCACCCTCTGCCCTGCCTGCCTGGCCTCGGA
  GGACCCGCATGCCCCATCCGGCAGCTCCTCCGGTGTGCTCACAGGACACTTAAACCAGGA
  CGAGGCATGGCCCCGAGACACTGGCAGGTTTGTGAGCCTCTTCCCACCCCCTGTGCCCCC
  ACCCTTGCCTGGTTCCTGGTGGCTCAGGGCAAGGAGTGGCCCTGGGCGCCCGTGTCGGTC
  CTGTTTCCGCTGCCCTTATCTCAAAGTCCGTGGCTGTTTCCCCTTCACTGACTCAGCTAG
  ACCCGTAAGCCCACCCTTCCCACAGGGAACAGGCTGCTCCCACCTGGGTYCCGCTGTGGC
  CACGGTGGGCAGCCCAAAAGATCAGGGGTGGAGGGGCTTCCAGGCTGTACTCCTGCCCCG
  TGGGCCCCGTTCTAGAGGTGCCCTTGGCAGGACCGTGCAGGCAGCTCCCCTCTGTGGGGC
  AGTATCTGGTCCTGTGCCCCAGCTGCCAAAGGAGAGTGGGGGCCATGCCCCGCAGTCAGT
  GTTGGGGGGCTCCTGCCTACAGGGAGAGGGATGGTGGGGAAGGGGTGGAGCTGGGGGCAG
  GGCAGCACAGGGAATATTTTTGTAACTAACTAACTGCTGTGGTTGGAGCGAATGGAAGTT
  GGGTGATTTTAAGTTATTGTTGCCAAAGAGATGTAAAGTTTATTGTTGCTTCGCAGGGGG
  ATTTGTTTTGTGTTTTGTTTGAGGCTTAGAACGCTGGTGCAATGTTTTCTTGTTCCTTGT
  TTTTTAAGAGAAATTAAGCTAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001080395
• ORF Size: 4206 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid.

Reference Data

• RefSeq: NM_001080395.1, NP_001073864.1
• RefSeq Size: 5843
• RefSeq ORF: 4206
• Locus ID: 9625
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).