HDAC7 (NM_001098416) Human Untagged Clone

CAT#: SC316282

HDAC7 (untagged)-Human histone deacetylase 7 (HDAC7), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HDAC7
• Synonyms: HD7; HD7A; HDAC7A
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001098416 edited
  CAGCCTCCGGCGACTGGGGGGATGTGAGGCCGGCGCCCCAGCCCCCCGCCCCGCCATGAG
  CCCCCCGCTCTGAGGGCCCCGGCCCCTGGATGCACAGCCCCGGCGCTGATGGGACCCAGG
  TGAGCCCGGGTGCCCACTACTGCAGCCCCACTGGCGCAGGCTGCCCCAGGCCCTGTGCAG
  ACACACCAGGCCCTCAGCCGCAGCCCATGGACCTGCGGGTGGGCCAGCGGCCCCCAGTGG
  AGCCCCCACCAGAGCCCACATTGCTGGCCCTGCAGCGTCCCCAGCGCCTGCACCACCACC
  TCTTCCTAGCAGGCCTGCAGCAGCAGCGCTCGGTGGAGCCCATGAGGCTCTCCATGGACA
  CGCCGATGCCCGAGTTGCAGGTGGGACCCCAGGAACAAGAGCTGCGGCAGCTTCTCCACA
  AGGACAAGAGCAAGCGAAGTGCTGTAGCCAGCAGCGTGGTCAAGCAGAAGCTAGCGGAGG
  TGATTCTGAAAAAACAGCAGGCGGCCCTAGAAAGAACAGTCCATCCCAACAGCCCCGGCA
  TTCCCTACAGAACCCTGGAGCCCCTGGAGACGGAAGGAGCCACCCGCTCCATGCTCAGCA
  GCTTTTTGCCTCCTGTTCCCAGCCTGCCCAGTGACCCCCCAGAGCACTTCCCTCTGCGCA
  AGACAGTCTCTGAGCCCAACCTGAAGCTGCGCTATAAGCCCAAGAAGTCCCTGGAGCGGA
  GGAAGAATCCACTGCTCCGAAAGGAGAGTGCGCCCCCCAGCCTCCGGCGGCGGCCCGCAG
  AGACCCTCGGAGACTCCTCCCCAAGTAGTAGCAGCACGCCCGCATCAGGGTGCAGCTCCC
  CCAATGACAGCGAGCACGGCCCCAATCCCATCCTGGGCTCGGAGGCTGACAGTGACCGCA
  GGACCCATCCGACTCTGGGCCCTCGGGGGCCAATCCTGGGGAGCCCCCACACTCCCCTCT
  TCCTGCCCCATGGCTTGGAGCCCGAGGCTGGGGGCACCTTGCCCTCTCGCCTGCAGCCCA
  TTCTCCTCCTGGACCCCTCAGGCTCTCATGCCCCGCTGCTGACTGTGCCCGGGCTTGGGC
  CCTTGCCCTTCCACTTTGCCCAGTCCTTAATGACCACCGAGCGGCTCTCTGGGTCAGGCC
  TCCACTGGCCACTGAGCCGGACTCGCTCAGAGCCCCTGCCCCCCAGTGCCACCGCTCCCC
  CACCGCCGGGCCCCATGCAGCCCCGCCTGGAGCAGCTCAAAACTCACGTCCAGGTGATCA
  AGAGGTCAGCCAAGCCGAGTGAGAAGCCCCGGCTGCGGCAGATACCCTCGGCTGAAGACC
  TGGAGACAGATGGCGGGGGACCGGGCCAGGTGGTGGACGATGGCCTGGAGCACAGGGAGC
  TGGGCCATGGGCAGCCTGAGGCCAGAGGCCCCGCTCCTCTCCAGCAGCACCCTCAGGTGT
  TGCTCTGGGAACAGCAGCGACTGGCTGGGCGGCTCCCCCGGGGCAGCACCGGGGACACTG
  TGCTGCTTCCTCTGGCCCAGGGTGGGCACCGGCCTCTGTCCCGGGCTCAGTCTTCCCCAG
  CCGCACCTGCCTCACTGTCAGCCCCAGAGCCTGCCAGCCAGGCCCGAGTCCTCTCCAGCT
  CAGAGACCCCTGCCAGGACCCTGCCCTTCACCACAGGGCTGATCTATGACTCGGTCATGC
  TGAAGCACCAGTGCTCCTGCGGTGACAACAGCAGGCACCCGGAGCACGCCGGCCGCATCC
  AGAGCATCTGGTCCCGGCTGCAGGAGCGGGGGCTCCGGAGCCAGTGTGAGTGTCTCCGAG
  GCCGGAAGGCCTCCCTGGAAGAGCTGCAGTCGGTCCACTCTGAGCGGCACGTGCTCCTCT
  ACGGCACCAACCCGCTCAGCCGCCTCAAACTGGACAACGGGAAGCTGGCAGGGCTCCTGG
  CACAGCGGATGTTTGTGATGCTGCCCTGTGGTGGGGTTGGGGTGGACACTGACACCATCT
  GGAATGAGCTTCATTCCTCCAATGCAGCCCGCTGGGCCGCTGGCAGTGTCACTGACCTCG
  CCTTCAAAGTGGCTTCTCGTGAGCTAAAGAATGGTTTCGCTGTGGTGCGGCCCCCAGGAC
  ACCATGCAGATCATTCAACAGCCATGGGCTTCTGCTTCTTCAACTCAGTGGCCATCGCCT
  GCCGGCAGCTGCAACAGCAGAGCAAGGCCAGCAAGATCCTCATTGTAGACTGGGACGTGC
  ACCATGGCAACGGCACCCAGCAAACCTTCTACCAAGACCCCAGTGTGCTCTACATCTCCC
  TGCATCGCCATGACGACGGCAACTTCTTCCCGGGGAGTGGGGCTGTGGATGAGGTAGGGG
  CTGGCAGCGGTGAGGGCTTCAATGTCAATGTGGCCTGGGCTGGAGGTCTGGACCCCCCCA
  TGGGGGATCCTGAGTACCTGGCTGCTTTCAGGATAGTCGTGATGCCCATCGCCCGAGAGT
  TCTCTCCAGACCTAGTCCTGGTGTCTGCTGGATTTGATGCTGCTGAGGGTCACCCGGCCC
  CACTGGGTGGCTACCATGTTTCTGCCAAATGTTTTGGATACATGACGCAGCAACTGATGA
  ACCTGGCAGGAGGCGCAGTGGTGCTGGCCTTGGAGGGTGGCCATGACCTCACAGCCATCT
  GTGACGCCTCTGAGGCCTGTGTGGCTGCTCTTCTGGGTAACAGGGTGGATCCCCTTTCAG
  AAGAAGGCTGGAAACAGAAACCCAACCTCAATGCCATCCGCTCTCTGGAGGCCGTGATCC
  GGGTGCACAGTAAATACTGGGGCTGCATGCAGCGCCTGGCCTCCTGTCCAGACTCCTGGG
  TGCCTAGAGTGCCAGGGGCTGACAAAGAAGAAGTGGAGGCAGTGACCGCACTGGCGTCCC
  TCTCTGTGGGCATCCTGGCTGAAGATAGGCCCTCGGAGCAGCTGGTGGAGGAGGAAGAAC
  CTATGAATCTCTAAGGCTCTGGAACCATCTGCCCGCCCACCATGCCCTTGGGACCTGGTT
  CTCTTCTAACCCCTGGCAATAGCCCCCATTCCTGGGTCTTTAGAGATCCTGTGGGCAAGT
  AGTTGGAACCAGAGAACAGCCTGCCTGCTTTGACAGTTATCCCAGGGAGCGTGAGAAAAT
  CCCTGGGTCTAGAATGGGAACTGGAGAGGACCCTGAGAGGAGACGGGCTGGGCGGCGACC
  CCCACAGGGCTCTCGAGAACAGATTCTCCCCTCCAGTATGGGCCCTGGCTGTGGCCCCCA
  TTCCTCAGGACTGCACAGAGGAGGACTGGCTCCGGCTCCGTCGGGCTCACCCTTAACCAC
  TATTCCTGGCTCTGCAAACCCCAGACTTTGCACACAGCCCCAGGCTCCACACAGAAATGT
  GAACTTGGCCTCAGACAGGCTGGCCCTTCCTAGGCTCTAGGGGCTAGGGGGGAGTGGGGA
  GCCAAGAGGTCCCATATTCCTGAGTGCAGGGGTAGTCCCTCTCACCTGCTTCCTCAGACG
  ACTCTGGAAGCTT
  
• Restriction Sites: Please inquire
• ACCN: NM_001098416
• ORF Size: 2865 bp
• Insert Size: 3500
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001098416.1, NP_001091886.1
• RefSeq Size: 4084
• RefSeq ORF: 2865
• Locus ID: 51564
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4) lacks an alternate in-frame exon in the mid-coding region, compared to variant 1. The resulting isoform (d) has the same N- and C-termini but is shorter than isoform a.