CMG1 (IFT74) (NM_001099224) Human Untagged Clone

CAT#: SC316512

IFT74 (untagged)-Human intraflagellar transport 74 homolog (Chlamydomonas) (IFT74), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFT74
• Synonyms: BBS20; CCDC2; CMG-1; CMG1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001099224, the custom clone sequence may differ by one or more nucleotides
  ATGGCCAGCAATCACAAATCTTCAGCAGCTCGCCCTGTTTCAAGAGGTGGAGTTGGGTTA
  ACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGAAATATTCGAGTGGCAACTGCA
  ATGCCACCTGGGACAGCAAGACCAGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTT
  CTGTCTTCTCAAATCAAAGTTGCCCATCGCCCTGTAACACAACAAGGTTTGACTGGAATG
  AAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTACTATCTTGGGCTT
  CTTAGAAGTAAAATAAGTGAACTTACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAA
  ATGTACAATCAAGAGAATTCAGTATATTTGTCATATGAAAAGAGGGCTGAGACTTTAGCT
  GTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTACAACATGTTGGTAGATAAACTT
  AATACCAACACTGAAATGGAAGAAGTAATGAATGATTACAATATGCTTAAAGCTCAAAAT
  GATCGAGAAACACAAAGTTTGGATGTCATATTTACTGAAAGACAAGCGAAAGAAAAACAA
  ATCAGAAGTGTCGAAGAAGAAATTGAACAGGAAAAACAAGCAACAGATGACATTATCAAA
  AATATGTCTTTTGAAAACCAAGTCAAGTACCTAGAGATGAAAACCACAAATGAGAAACTG
  TTACAGGAATTAGATACACTTCAACAACAATTGGATTCACAGAACATGAAAAAAGAGAGC
  CTGGAAGCAGAAATAGCTCACTCCCAGGTGAAACAGGAGGCGGTATTGCTGCATGAAAAA
  CTTTATGAGTTGGAGTCCCATCGAGATCAAATGATTGCAGAAGACAAAAGCATAGGATCT
  CCAATGGAAGAGAGAGAGAAATTACTTAAGCAGATTAAAGATGATAATCAGGAAATAGCC
  AGCATGGAAAGACAGTTAACAGATACAAAAGAAAAGATAAATCAGTTTATTGAAGAAATT
  AGACAACTTGACATGGATTTAGAGGAACACCAAGATCCTACCAACTATGGATGGAAAATA
  CTTGAAAAAAATACAGGAAGTTTCAAAAAGCAAGTT
  
• Restriction Sites: Please inquire
• ACCN: NM_001099224
• ORF Size: 1119 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001099224.1, NP_001092694.1
• RefSeq Size: 1571
• RefSeq ORF: 1119
• Locus ID: 80173
• Gene Summary: This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (4) lacks several exons in the 3' coding region, uses an alternate 3' terminal exon, and differs in the 3' UTR, compared to variant 1. The encoded isoform (b) has a shorter and distinct C-terminus, compared to isoform (a).