CMG1 (IFT74) (NM_001099222) Human Untagged Clone

CAT#: SC316551

IFT74 (untagged)-Human intraflagellar transport 74 homolog (Chlamydomonas) (IFT74), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFT74
• Synonyms: BBS20; CCDC2; CMG-1; CMG1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001099222, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCAGCAATCACAAATCTTCAGCAGCTCGCCCTGTTTCAAGAGGTGGAGTTGGGTTAACAGGAAGGC
  CTCCTTCTGGGATACGACCCCTATCAGGAAATATTCGAGTGGCAACTGCAATGCCACCTGGGACAGCAAG
  ACCAGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCTCAAATCAAAGTTGCCCATCGC
  CCTGTAACACAACAAGGTTTGACTGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGACA
  AATCTTACTATCTTGGGCTTCTTAGAAGTAAAATAAGTGAACTTACAACTGAAGTTAATAAACTTCAGAA
  GGGAATAGAAATGTACAATCAAGAGAATTCAGTATATTTGTCATATGAAAAGAGGGCTGAGACTTTAGCT
  GTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTACAACATGTTGGTAGATAAACTTAATACCAACA
  CTGAAATGGAAGAAGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAAACACAAAGTTT
  GGATGTCATATTTACTGAAAGACAAGCGAAAGAAAAACAAATCAGAAGTGTCGAAGAAGAAATTGAACAG
  GAAAAACAAGCAACAGATGACATTATCAAAAATATGTCTTTTGAAAACCAAGTCAAGTACCTAGAGATGA
  AAACCACAAATGAGAAACTGTTACAGGAATTAGATACACTTCAACAACAATTGGATTCACAGAACATGAA
  AAAAGAGAGCCTGGAAGCAGAAATAGCTCACTCCCAGGTGAAACAGGAGGCGGTATTGCTGCATGAAAAA
  CTTTATGAGTTGGAGTCCCATCGAGATCAAATGATTGCAGAAGACAAAAGCATAGGATCTCCAATGGAAG
  AGAGAGAGAAATTACTTAAGCAGATTAAAGATGATAATCAGGAAATAGCCAGCATGGAAAGACAGTTAAC
  AGATACAAAAGAAAAGATAAATCAGTTTATTGAAGAAATTAGACAACTTGACATGGATTTAGAGGAACAC
  CAAGGTGAAATGAACCAGAAATACAAGGAGCTAAAGAAAAGGGAGGAACATATGGACACTTTTATTGAGA
  CTTTTGAGGAAACAAAGAATCAGGAACTGAAACGAAAGGCACAGATAGAAGCCAACATTGTTGCACTCTT
  GGAGCACTGCAGTCGAAATATAAATCGTATAGAACAGATATCCTCTATCACCAATCAAGAGCTAAAGATG
  ATGCAGGATGACCTCAATTTTAAATCTACTGAAGTGCAGAAATCACAAAGTACAGCTCAGAATTTGACTT
  CAGACATTCAACGTCTGCAGTTGGATCTGCAGAAAATGGAGCTTCTAGAAAGTAAGATGACTGAAGAACA
  GCATTCTCTAAAAAGCAAAATTAAGCAAATGACAACTGATCTGGAGATATATAATGATTTGCCAGCTTTA
  AAATCATCAGGTGAAGAAAAGATAAAGAAATTACATCAGGAGAGAATGATATTATCAACCCACAGAAATG
  CCTTTAAGAAAATAATGGAGAAGCAAAACATAGAGTATGAGGCACTAAAAACACAATTGCAAGAAAATGA
  GACACATTCTCAGCTTACAAATTTGGAGAGAAAGTGGCAACACCTTGAGCAAAATAATTTTGCGATGAAA
  GAATTCATAGCAACCAAGAGTCAAGAGAGTGATTACCAGCCAATTAAGAAAAATGTGACCAAGCAGATTG
  CAGAGTACAATAAAACCATCGTGGATGCTTTACATAGCACCAGCGGAAACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001099222
• ORF Size: 1803 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001099222.1, NP_001092692.1
• RefSeq Size: 2183
• RefSeq ORF: 1803
• Locus ID: 80173
• Gene Summary: This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.