Histone acetyltransferase MYST3 (KAT6A) (NM_001099412) Human Untagged Clone

CAT#: SC316616

KAT6A (untagged)-Human MYST histone acetyltransferase (monocytic leukemia) 3 (MYST3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KAT6A
• Synonyms: MOZ; MRD32; MYST3; RUNXBP2; ZC2HC6A; ZNF220
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001099412, the custom clone sequence may differ by one or more nucleotides
  ATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTTTGGAGGCCATCAAAAAAGTG
  AAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCAT
  GGCTTGGATCGTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATT
  TTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGATCCTGATAATCCTGGGCGAATA
  GCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAAT
  AAACTGATAAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGC
  ATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCATTATTCGGAGGCAGTGCTGCC
  TCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTC
  CTTAAAGATGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAG
  AGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCTTCTTCCACATGAAAAGGATAAG
  CCGGTTGCTGAACCAATCCCCATCTGTAGTTTCTGTCTTGGTACAAAAGAACAAAACCGA
  GAAAAGAAGCCAGAGGAACTCATCTCCTGTGCCGACTGTGGCAACAGTGGCCATCCATCC
  TGTTTAAAGTTTTCCCCTGAACTAACGGTTCGAGTGAAGGCCTTACGGTGGCAGTGCATC
  GAGTGTAAAACATGCAGCTCCTGTCGAGATCAAGGCAAAAATGCGGATAACATGCTCTTT
  TGTGATTCATGTGACCGAGGTTTTCACATGGAGTGTTGTGATCCGCCACTCACCCGTATG
  CCAAAAGGCATGTGGATATGTCAAATATGTCGACCTAGGAAAAAAGGACGAAAACTTCTA
  CAAAAGAAGGCAGCACAGATAAAACGGCGCTATACTAATCCAATAGGACGTCCAAAAAAC
  AGGTTAAAGAAACAAAACACGGTATCAAAAGGTCCCTTCAGCAAAGTTCGAACTGGCCCT
  GGAAGGGGTAGGAAACGAAAAATCACTCTTTCCAGCCAATCAGCATCATCATCATCAGAA
  GAAGGATATTTAGAGCGGATAGATGGCTTGGACTTCTGCAGAGATAGCAATGTCTCCTTG
  AAGTTCAACAAGAAAACCAAAGGGCTCATTGATGGCCTTACCAAATTTTTTACCCCTTCC
  CCTGATGGGCGGAAAGCTCGGGGGGAAGTGGTGGACTACTCTGAGCAATATCGAATCAGA
  AAGAGGGGCAACAGGAAATCAAGCACTTCAGATTGGCCCACAGACAATCAGGATGGCTGG
  GATGGCAAACAAGAAAATGAGGAGCGACTTTTTGGGAGCCAGGAAATCATGACTGAGAAA
  GATATGGAATTATTTCGTGATATCCAAGAACAAGCACTGCAGAAAGTTGGAGTGACTGGT
  CCCCCTGATCCACAAGTCCGCTGTCCCTCTGTCATTGAGTTTGGGAAGTATGAAATTCAC
  ACCTGGTACTCCTCCCCATATCCTCAAGAATACTCAAGGCTGCCCAAATTGTATCTTTGT
  GAATTTTGTCTAAAATATATGAAAAGTAGAACTATTCTGCAGCAGCACATGAAGAAATGT
  GGTTGGTTCCATCCTCCTGCCAATGAGATTTACAGAAAGAATAATATTTCTGTCTTTGAG
  GTTGATGGGAATGTGAGTACCATTTATTGTCAAAACCTGTGTCTTTTGGCAAAGTTGTTT
  CTTGACCACAAAACCCTCTATTACGATGTGGAGCCATTTCTTTTTTATGTACTAACACAG
  AATGATGTCAAGGGCTGCCACCTTGTTGGCTACTTTTCTAAGGAAAAGCACTGCCAACAG
  AAGTACAATGTTTCCTGTATAATGATTCTTCCTCAATACCAGCGTAAGGGCTATGGCAGG
  TTTCTCATCGATTTCAGTTATTTGTTATCAAAGCGTGAAGGCCAAGCAGGGTCTCCAGAG
  AAACCGTTATCTGATCTGGGTCGTCTTTCCTACATGGCATATTGGAAAAGTGTAATATTG
  GAGTGCCTTTATCACCAAAATGACAAGCAGATCAGCATTAAGAAGTTAAGCAAGTTGACT
  GGAATCTGCCCTCAAGACATCACTTCCACACTCCACCACCTACGAATGCTGGACTTCCGT
  AGTGACCAATTTGTGATTATCCGCCGGGAAAAACTTATCCAGGATCACATGGCAAAGCTT
  CAGCTGAATTTGCGACCTGTAGATGTAGATCCAGAATGTTTGCGCTGGACTCCAGTCATA
  GTGTCCAACTCTGTGGTCTCAGAGGAGGAAGAAGAGGAGGCTGAGGAAGGAGAAAACGAA
  GAGCCACAGTGCCAGGAAAGAGAATTAGAGATCAGTGTGGGAAAGTCTGTGTCTCATGAG
  AACAAAGAACAAGATTCTTATTCAGTAGAAAGTGAAAAGAAACCAGAAGTTATGGCTCCA
  GTCAGTTCTACACGTTTGAGCAAACAAGTCCTTCCTCATGATAGTCTTCCTGCAAATAGC
  CAGCCATCTCGGAGGGGCCGCTGGGGGAGGAAGAACAGAAAAACCCAGGAACGTTTTGGT
  GATAAAGATTCTAAACTGCTCTTGGAAGAGACGTCTTCAGCTCCTCAGGAACAATATGGA
  GAATGTGGGGAGAAATCAGAAGCCACCCAGGAACAATACACTGAAAGTGAAGAACAGCTG
  GTGGCTTCTGAGGAGCAGCCAAGCCAGGACGGGAAACCTGACCTTCCCAAGAGAAGACTC
  AGTGAGGGGGTTGAGCCCTGGCGAGGACAGCTCAAGAAAAGCCCTGAGGCTCTGAAGTGC
  AGATTAACAGAAGGAAGTGAGAGGCTGCCCCGTCGCTACAGTGAGGGTGACAGGGCTGTC
  CTCAGGGGCTTCAGTGAGAGCAGCGAGGAGGAGGAGGAGCCGGAAAGCCCTCGGTCAAGC
  TCGCCACCAATTCTCACAAAGCCCACGCTGAAGCGAAAGAAACCATTTCTCCACCGAAGG
  AGGAGAGTCCGAAAGCGCAAACACCACAATAGCAGTGTAGTCACAGAAACTATTTCTGAG
  ACCACTGAAGTGTTAGATGAACCTTTTGAAGATTCTGACTCCGAGAGGCCAATGCCAAGA
  TTAGAACCCACGTTTGAGATCGATGAAGAAGAGGAGGAAGAGGATGAAAATGAACTTTTC
  CCTAGAGAATACTTCCGTCGTTTGTCTTCGCAGGATGTACTCAGGTGTCAGTCCTCTTCT
  AAGAGGAAGTCTAAAGATGAAGAAGAAGATGAAGAGTCAGATGATGCTGATGACACTCCT
  ATCTTAAAGCCAGTATCTCTTTTGCGAAAACGTGATGTGAAGAATTCTCCTCTTGAGCCA
  GATACATCCACACCTTTGAAAAAGAAAAAGGGATGGCCCAAAGGCAAGAGCCGCAAACCA
  ATCCACTGGAAGAAAAGACCTGGTCGAAAACCAGGATTTAAGTTGAGTCGGGAAATCATG
  CCAGTTTCTACTCAAGCATGCGTCATTGAGCCCATCGTTTCCATTCCTAAAGCTGGACGT
  AAACCCAAGATCCAGGAGAGTGAAGAAACTGTTGAGCCAAAAGAAGACATGCCCCTACCC
  GAGGAGAGGAAGGAGGAGGAGGAGATGCAAGCAGAGGCAGAAGAGGCTGAAGAGGGTGAG
  GAAGAGGATGCAGCCAGCAGTGAAGTCCCAGCAGCCTCTCCAGCAGACAGCAGCAATAGT
  CCTGAGACCGAAACCAAGGAGCCTGAGGTGGAGGAGGAAGAAGAGAAGCCCCGTGTCTCA
  GAGGAGCAGAGGCAGTCAGAGGAGGAGCAGCAGGAATTAGAGGAGCCAGAGCCAGAGGAG
  GAGGAAGATGCAGCTGCAGAGACTGCCCAGAATGACGACCACGACGCTGATGATGAGGAT
  GATGGCCACCTGGAGTCCACAAAGAAAAAGGAGCTAGAGGAACAGCCCACGAGGGAAGAT
  GTCAAGGAGGAGCCTGGTGTTCAAGAGTCTTTTTTAGATGCTAATATGCAGAAGAGTAGG
  GAAAAGATAAAGGATAAAGAGGAAACCGAGCTGGATTCCGAAGAGGAGCAGCCTTCCCAT
  GACACGTCCGTGGTGTCAGAGCAGATGGCTGGGTCTGAGGACGACCACGAAGAAGACTCC
  CACACTAAGGAAGAGTTAATCGAATTAAAAGAGGAGGAAGAGATTCCTCATAGTGAGCTG
  GATCTGGAAACTGTACAGGCAGTGCAGTCTTTGACTCAAGAAGAAAGCAGTGAGCATGAG
  GGCGCCTACCAGGACTGTGAGGAAACTCTTGCGGCGTGTCAGACCCTGCAGAGTTACACC
  CAGGCTGACGAGGACCCTCAGATGTCCATGGTTGAAGACTGTCATGCGTCAGAACATAAT
  AGCCCTATCTCCTCCGTTCAGTCTCACCCCAGCCAGTCAGTCCGTTCGGTCAGCAGTCCC
  AACGTGCCTGCCCTTGAGAGTGGCTACACCCAGATCAGCCCAGAACAAGGATCCCTGTCC
  GCACCCTCTATGCAGAACATGGAGACCAGCCCCATGATGGATGTGCCTTCCGTATCAGAC
  CACTCTCAGCAGGTGGTGGACAGCGGCTTCAGTGACCTGGGCAGCATTGAGAGCACCACT
  GAAAACTATGAGAACCCAAGCAGTTACGACTCCACGATGGGCGGCAGCATCTGTGGGAAC
  AGCTCTTCCCAGAGCAGCTGCTCCTACGGTGGGCTGTCGTCCTCCAGCAGCCTCACCCAG
  AGCAGCTGTGTGGTCACTCAGCAGATGGCCAGCATGGGCAGCAGCTGCAGCATGATGCAG
  CAGAGCAGCGTCCAGCCTGCTGCCAACTGCAGCATCAAGTCACCTCAGAGCTGCGTGGTG
  GAGAGGCCTCCCAGTAACCAGCAGCAGCAGCCGCCACCACCGCCTCCACAGCAGCCACAG
  CCGCCGCCGCCACAACCACAACCAGCACCACAGCCTCCACCACCCCAGCAGCAGCCGCAA
  CAGCAGCCGCAGCCTCAGCCCCAGCAGCCTCCACCCCCACCCCCTCCCCAGCAGCAGCCC
  CCGCTGTCACAGTGTAGTATGAATAACAGTTTCACCCCAGCTCCTATGATCATGGAGATA
  CCAGAATCTGGAAGCACTGGGAACATAAGTATCTATGAGAGGATTCCAGGGGATTTTGGT
  GCCGGCAGCTACTCTCAACCATCAGCCACCTTCAGCCTAGCCAAGCTGCAGCAGCTGACC
  AACACCATTATGGACCCTCATGCCATGCCTTATAGCCATTCTCCTGCTGTGACTTCCTAT
  GCAACCAGTGTTTCTCTGTCCAATACAGGACTGGCTCAGCTGGCTCCATCTCATCCCTTA
  GCTGGGACTCCTCAAGCACAAGCCACCATGACGCCACCCCCAAACTTGGCATCCACTACC
  ATGAACCTCACATCTCCTCTGCTTCAGTGCAACATGTCTGCCACCAACATTGGCATTCCT
  CACACGCAGAGATTGCAAGGGCAAATGCCAGTGAAGGGGCACATTTCCATCCGCTCCAAG
  TCTGCGCCACTGCCCTCTGCGGCTGCTCACCAGCAGCAGCTGTATGGCCGTAGCCCATCG
  GCAGTTGCCATGCAGGCTGGCCCTCGCGCACTGGCTGTTCAGCGTGGCATGAACATGGGG
  GTTAATCTGATGCCTACTCCCGCCTATAATGTCAATTCCATGAATATGAACACCTTGAAT
  GCCATGAACAGCTATCGAATGACACAGCCCATGATGAACAGCAGTTACCATAGTAACCCT
  GCCTACATGAACCAGACAGCACAGTATCCTATGCAGATGCAGATGGGAATGATGGGGAGC
  CAGGCCTATACCCAGCAGCCTATGCAGCCTAACCCTCATGGGAACATGATGTACACAGGC
  CCCTCCCATCACAGCTACATGAACGCTGCTGGCGTGCCCAAGCAGTCACTCAACGGACCT
  TACATGAGAAGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001099412
• ORF Size: 6015 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001099412.1, NP_001092882.1
• RefSeq Size: 9285
• RefSeq ORF: 6015
• Locus ID: 7994
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 all encode the same protein.