ERLIN1 (NM_001100626) Human Untagged Clone

CAT#: SC316728

ERLIN1 (untagged)-Human ER lipid raft associated 1 (ERLIN1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERLIN1
• Synonyms: C10orf69; Erlin-1; KE04; KEO4; SPFH1; SPG62
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001100626, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAATATGACTCAAGCCCGGGTTCTGGTGGCTGCAGTGGTGGGGTTGGTGGCTGTCCTGCTCTACGCCT
  CCATCCACAAGATTGAGGAGGGCCATCTGGCTGTGTACTACAGGGGAGGAGCTTTACTAACTAGCCCCAG
  TGGACCAGGCTATCATATCATGTTGCCTTTCATTACTACGTTCAGATCTGTGCAGACAACACTACAAACT
  GATGAAGTTAAAAATGTGCCTTGTGGAACAAGTGGTGGGGTCATGATCTATATTGACCGAATAGAAGTGG
  TTAATATGTTGGCTCCTTATGCAGTGTTTGATATCGTGAGGAACTATACTGCAGATTATGACAAGACCTT
  AATCTTCAATAAAATCCACCATGAGCTGAACCAGTTCTGCAGTGCCCACACACTTCAGGAAGTTTACATT
  GAATTGTTTGATCAAATAGATGAAAACCTGAAGCAAGCTCTGCAGAAAGACTTAAACCTCATGGCCCCAG
  GTCTCACTATACAGGCTGTGCGTGTTACAAAACCCAAAATCCCAGAAGCCATAAGAAGAAATTTTGAGTT
  AATGGAGGCTGAGAAGACAAAACTCCTTATAGCTGCACAGAAACAAAAGGTTGTGGAAAAAGAAGCTGAG
  ACAGAGAGGAAAAAGGCAGTTATAGAAGCAGAGAAGATTGCACAAGTGGCAAAAATTCGGTTTCAGCAGA
  AAGTGATGGAAAAAGAAACTGAAAAGCGCATTTCTGAAATCGAAGATGCTGCATTCCTGGCCCGAGAGAA
  AGCGAAAGCAGATGCTGAATATTATGCTGCACACAAATATGCCACCTCAAACAAGCACAAGTTGACCCCG
  GAATATCTGGAGCTCAAAAAGTACCAGGCCATTGCTTCTAACAGTAAGATCTATTTTGGCAGCAACATCC
  CTAACATGTTCGTGGACTCCTCATGTGCTTTGAAATATTCAGATATTAGGACTGGAAGAGAAAGCTCACT
  CCCCTCTAAGGAGGCTCTTGAACCCTCTGGAGAGAACGTCATCCAAAACAAAGAGAGCACAGGTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001100626
• ORF Size: 1047 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001100626.1, NP_001094096.1
• RefSeq Size: 3206
• RefSeq ORF: 1047
• Locus ID: 10613
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]
  Transcript Variant: This variant (2) differs in its 5' UTR compared to variant 1. Variants 1-6 all encode the same isoform (a).