ECE2 (NM_001100121) Human Untagged Clone

CAT#: SC316832

ECE2 (untagged)-Human endothelin converting enzyme 2 (ECE2), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ECE2
• Synonyms: EEF1AKMT4
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001100121, the custom clone sequence may differ by one or more nucleotides
  ATGAACGTCGCGCTGCAGGAGCTGGGAGCTGGCAGCAACATGGTGGAGTACAAACGGGCC
  ACGCTTCGGGATGAAGACGCACCCGAGACCCCCGTAGAGGGCGGGGCCTCCCCGGACGCC
  ATGGAGGTGGGATTCCAGAAGGGGACAAGACAGCTGTTAGGCTCACGCACGCAGCTGGAG
  CTGGTCTTAGCAGGTGCCTCTCTACTGCTGGCTGCACTGCTTCTGGGCTGCCTTGTGGCC
  CTAGGGGTCCAGTACCACAGAGACCCATCCCACAGCACCTGCCTTACAGAGGCCTGCATT
  CGAGTGGCTGGAAAAATCCTGGAGTCCCTGGACCGAGGGGTGAGCCCCTGTGAGGACTTT
  TACCAGTTCTCCTGTGGGGGCTGGATTCGGAGGAACCCCCTGCCCGATGGGCGTTCTCGC
  TGGAACACCTTCAACAGCCTCTGGGACCAAAACCAGGCCATACTGAAGCACCTGCTTGAA
  AACACCACCTTCAACTCCAGCAGTGAAGCTGAGCAGAAGACACAGCGCTTCTACCTATCT
  TGCCTACAGGTGGAGCGCATTGAGGAGCTGGGAGCCCAGCCACTGAGAGACCTCATTGAG
  AAGATTGGTGGTTGGAACATTACGGGGCCCTGGGACCAGGACAACTTTATGGAGGTGTTG
  AAGGCAGTAGCAGGGACCTACAGGGCCACCCCATTCTTCACCGTCTACATCAGTGCCGAC
  TCTAAGAGTTCCAACAGCAATGTTATCCAGGTGGACCAGTCTGGGCTCTTTCTGCCCTCT
  CGGGATTACTACTTAAACAGAACTGCCAATGAGAAAGTGCTCACTGCCTATCTGGATTAC
  ATGGAGGAACTGGGGATGCTGCTGGGTGGGCGGCCCACCTCCACGAGGGAGCAGATGCAG
  CAGGTGCTGGAGTTGGAGATACAGCTGGCCAACATCACAGTGCCCCAGGACCAGCGGCGC
  GACGAGGAGAAGATCTACCACAAGATGAGCATTTCGGAGCTGCAGGCTCTGGCGCCCTCC
  ATGGACTGGCTTGAGTTCCTGTCTTTCTTGCTGTCACCATTGGAGTTGAGTGACTCTGAG
  CCTGTGGTGGTGTATGGGATGGATTATTTGCAGCAGGTGTCAGAGCTCATCAACCGCACG
  GAACCAAGCATCCTGAACAATTACCTGATCTGGAACCTGGTGCAAAAGACAACCTCAAGC
  CTGGACCGACGCTTTGAGTCTGCACAAGAGAAGCTGCTGGAGACCCTCTATGGCACTAAG
  AAGTCCTGTGTGCCGAGGTGGCAGACCTGCATCTCCAACACGGATGACGCCCTTGGCTTT
  GCTTTGGGGTCCCTCTTCGTGAAGGCCACGTTTGACCGGCAAAGCAAAGAAATTGCAGAG
  GGGATGATCAGCGAAATCCGGACCGCATTTGAGGAGGCCCTGGGACAGCTGGTTTGGATG
  GATGAGAAGACCCGCCAGGCAGCCAAGGAGAAAGCAGATGCCATCTATGATATGATTGGT
  TTCCCAGACTTTATCCTGGAGCCCAAAGAGCTGGATGATGTTTATGACGGGTACGAAATT
  TCTGAAGATTCTTTCTTCCAAAACATGTTGAATTTGTACAACTTCTCTGCCAAGGTTATG
  GCTGACCAGCTCCGCAAGCCTCCCAGCCGAGACCAGTGGAGCATGACCCCCCAGACAGTG
  AATGCCTACTACCTTCCAACTAAGAATGAGATCGTCTTCCCCGCTGGCATCCTGCAGGCC
  CCCTTCTATGCCCGCAACCACCCCAAGGCCCTGAACTTCGGTGGCATCGGTGTGGTCATG
  GGCCATGAGTTGACGCATGCCTTTGATGACCAAGGGCGCGAGTATGACAAAGAAGGGAAC
  CTGCGGCCCTGGTGGCAGAATGAGTCCCTGGCAGCCTTCCGGAACCACACGGCCTGCATG
  GAGGAACAGTACAATCAATACCAGGTCAATGGGGAGAGGCTCAACGGCCGCCAGACGCTG
  GGGGAGAACATTGCTGACAACGGGGGGCTGAAGGCTGCCTACAATGCTTACAAAGCATGG
  CTGAGAAAGCATGGGGAGGAGCAGCAACTGCCAGCCGTGGGGCTCACCAACCACCAGCTC
  TTCTTCGTGGGATTTGCCCAGGTGTGGTGCTCGGTCCGCACACCAGAGAGCTCTCACGAG
  GGGCTGGTGACCGACCCCCACAGCCCTGCCCGCTTCCGCGTGCTGGGCACTCTCTCCAAC
  TCCCGTGACTTCCTGCGGCACTTCGGCTGCCCTGTCGGCTCCCCCATGAACCCAGGGCAG
  CTGTGTGAGGTGTGG
  
• Restriction Sites: Please inquire
• ACCN: NM_001100121
• ORF Size: 2298 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001100121.1, NP_001093591.1
• RefSeq Size: 3249
• RefSeq ORF: 2298
• Locus ID: 9718
• Protein Families: Druggable Genome, Protease, Transmembrane
• Gene Summary: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (5) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (E) has a distinct N-terminus compared to isoform A.