Cyclin A1 (CCNA1) (NM_001111046) Human Untagged Clone
CAT#: SC317198
CCNA1 (untagged)-Human cyclin A1 (CCNA1), transcript variant 3
"NM_001111046" in other vectors (4)
Product Images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | CCNA1 |
Synonyms | CT146 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001111046, the custom clone sequence may differ by one or more nucleotides
ATGCACTGCAGCAACCCCAAGAGTGGAGTTGTGCTGGCTACAGTGGCCCGAGGTCCCGAT GCTTGTCAGATACTCACCAGAGCCCCGCTGGGCCAGGATCCCCCGCAGAGGACAGTGCTA GGGCTGCTAACTGCAAATGGGCAGTACAGGAGGACCTGTGGCCAGGGGATCACAAGAATC AGGTGTTATTCTGGATCAGAAAATGCCTTCCCTCCAGCTGGAAAGAAAGCACTCCCTGAC TGTGGGGTCCAAGAGCCCCCCAAGCAAGGGTTTGACATCTACATGGATGAACTAGAGCAG GGGGACAGAGACAGCTGCTCGGTCAGAGAGGGGATGGCATTTGAGGATGTGTATGAAGTA GACACCGGCACACTCAAGTCAGACCTGCACTTCCTGCTGGATTTCAACACAGTTTCCCCT ATGCTGGTAGATTCATCTCTCCTCTCCCAGTCTGAAGATATATCCAGTCTTGGCACAGAT GTGATAAATGTGACTGAATATGCTGAAGAAATTTATCAGTACCTTAGGGAAGCTGAAATA AGGCACAGACCCAAAGCACACTACATGAAGAAGCAGCCAGACATCACGGAAGGCATGCGC ACGATTCTGGTGGACTGGCTGGTGGAGGTTGGGGAAGAATATAAACTTCGAGCAGAGACC CTGTATCTGGCTGTCAACTTCCTGGACAGGTTCCTTTCATGTATGTCTGTTCTGAGAGGG AAACTGCAGCTCGTAGGAACAGCAGCTATGCTTTTGGCTTCGAAATATGAAGAGATATAT CCTCCTGAAGTAGACGAGTTTGTCTATATCACCGATGATACATACACAAAACGACAACTG TTAAAAATGGAACACTTGCTTCTGAAAGTTCTAGCTTTTGATCTGACAGTACCAACCACC AACCAGTTTCTCCTTCAGTACTTGAGGCGACAAGGAGTGTGCGTCAGGACTGAGAACCTG GCTAAGTACGTAGCAGAGCTGAGTCTACTTGAAGCAGATCCATTCTTGAAATATCTTCCT TCACTGATAGCTGCAGCAGCTTTTTGCCTGGCAAACTATACTGTGAACAAGCACTTTTGG CCAGAAACCCTTGCTGCATTTACAGGGTATTCATTAAGTGAAATTGTGCCTTGCCTGAGT GAGCTTCATAAAGCGTACCTTGATATACCCCATCGACCTCAGCAAGCAATTAGGGAGAAG TACAAGGCTTCAAAGTACCTGTGTGTGTCCCTCATGGAGCCACCTGCAGTTCTTCTTCTA CAA |
Restriction Sites | Please inquire |
ACCN | NM_001111046 |
ORF Size | 1266 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Reference Data | |
RefSeq | NM_001111046.1, NP_001104516.1 |
RefSeq Size | 1844 |
RefSeq ORF | 1266 |
Locus ID | 8900 |
Protein Families | Druggable Genome |
Protein Pathways | Acute myeloid leukemia, Cell cycle, Pathways in cancer, Progesterone-mediated oocyte maturation |
Gene Summary | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. Transcript variants 3 and 4 encode isoform c, which has a shorter N-terminus when compared to isoform a. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC225673 | CCNA1 (Myc-DDK-tagged)-Human cyclin A1 (CCNA1), transcript variant 3 |
USD 420.00 |
|
RG225673 | CCNA1 (GFP-tagged) - Human cyclin A1 (CCNA1), transcript variant 3 |
USD 460.00 |
|
RC225673L3 | Lenti-ORF clone of CCNA1 (Myc-DDK-tagged)-Human cyclin A1 (CCNA1), transcript variant 3 |
USD 620.00 |
|
RC225673L4 | Lenti-ORF clone of CCNA1 (mGFP-tagged)-Human cyclin A1 (CCNA1), transcript variant 3 |
USD 620.00 |
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