SNX6 (NM_152233) Human Untagged Clone

CAT#: SC317669

SNX6 (untagged)-Human sorting nexin 6 (SNX6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SNX6
• Synonyms: MSTP010; TFAF2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_152233, the custom clone sequence may differ by one or more nucleotides
  ATGCGCGCCTGCGCCGGCCCTCGCCTCGGAGCAGCCATGATGGAAGGCCTGGACGACGGC
  CCGGACTTCCTCTCAGAAGAGGACCGCGGACTTAAAGCAATAAATGTAGATCTTCAAAGT
  GATGCTGCTCTGCAGGTGGACATTTCTGATGCTCTTAGTGAGCGGGATAAAGTAAAATTC
  ACTGTTCACACAAAGAGTTCATTGCCAAATTTTAAACAAAACGAGTTTTCAGTTGTTCGG
  CAACATGAGGAATTTATCTGGCTTCATGATTCCTTTGTTGAAAATGAAGACTATGCAGGT
  TATATCATTCCACCAGCACCACCAAGACCTGATTTTGATGCTTCAAGGGAAAAACTACAG
  AAGCTTGGTGAAGGAGAAGGGTCAATGACGAAGGAAGAATTCACAAAGATGAAACAGGAA
  CTGGAAGCTGAATATTTGGCAATATTCAAGAAGACAGTTGCGATGCATGAAGTGTTCCTG
  TGTCGTGTGGCAGCACATCCTATTTTGAGAAGAGATTTAAATTTCCATGTCTTCTTGGAA
  TATAATCAAGATTTGAGTGTGCGAGGAAAAAATAAAAAAGAGAAACTTGAAGACTTCTTT
  AAAAACATGGTTAAATCAGCAGATGGAGTAATCGTTTCAGGAGTAAAGGATGTAGATGAT
  TTCTTTGAGCACGAACGAACATTTCTTTTGGAGTATCATAACCGAGTTAAGGATGCATCT
  GCTAAATCTGATAGAATGACAAGATCCCACAAAAGTGCTGCAGATGATTACAATAGAATT
  GGTTCTTCATTATATGCTTTAGGAACTCAGGATTCTACAGATATATGCAAGTTTTTTCTC
  AAAGTTTCAGAACTGTTCGATAAAACAAGAAAAATAGAAGCACGAGTGTCTGCTGATGAA
  GACCTCAAACTTTCTGATCTTTTAAAATATTACTTAAGAGAATCTCAAGCTGCTAAGGAT
  CTCCTGTATCGAAGGTCTAGGTCACTAGTGGATTATGAAAATGCTAATAAAGCACTGGAT
  AAAGCAAGAGCAAAAAATAAAGATGTTCTACAGGCCGAAACTTCCCAACAATTATGTTGT
  CAGAAATTTGAAAAAATATCTGAGTCTGCAAAACAAGAACTTATAGATTTTAAGACAAGA
  AGAGTTGCTGCATTCAGAAAAAATTTAGTGGAACTGGCAGAGTTAGAACTGAAGCATGCA
  AAGGGTAATCTACAGTTGCTGCAGAACTGCCTGGCAGTGTTAAATGGAGACACA
  
• Restriction Sites: Please inquire
• ACCN: NM_152233
• ORF Size: 1257 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_152233.2, NP_689419.2
• RefSeq Size: 2975
• RefSeq ORF: 1257
• Locus ID: 58533
• Domains: PX
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) encodes the longest isoform (b). CCDS Note: The coding region has been updated to scale back the N-terminus to one that is more supported by available conservation data.