HPSE2 (NM_021828) Human Untagged Clone

CAT#: SC318019

HPSE2 (untagged)-Human heparanase 2 (HPSE2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HPSE2
• Synonyms: HPA2; HPR2; UFS; UFS1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_021828, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGGTGCTTTGTGCCTTCCCTGAAGCCATGCCCTCCAGCAACTCCCGCCCCCCCGCGTGCCTAGCCC
  CGGGGGCTCTCTACTTGGCTCTGTTGCTCCATCTCTCCCTTTCCTCCCAGGCTGGAGACAGGAGACCCTT
  GCCTGTAGACAGAGCTGCAGGTTTGAAGGAAAAGACCCTGATTCTACTTGATGTGAGCACCAAGAACCCA
  GTCAGGACAGTCAATGAGAACTTCCTCTCTCTGCAGCTGGATCCGTCCATCATTCATGATGGCTGGCTCG
  ATTTCCTAAGCTCCAAGCGCTTGGTGACCCTGGCCCGGGGACTTTCGCCCGCCTTTCTGCGCTTCGGGGG
  CAAAAGGACCGACTTCCTGCAGTTCCAGAACCTGAGGAACCCGGCGAAAAGCCGCGGGGGCCCGGGCCCG
  GATTACTATCTCAAAAACTATGAGGATGACATTGTTCGAAGTGATGTTGCCTTAGATAAACAGAAAGGCT
  GCAAGATTGCCCAGCACCCTGATGTTATGCTGGAGCTCCAAAGGGAGAAGGCAGCTCAGATGCATCTGGT
  TCTTCTAAAGGAGCAATTCTCCAATACTTACAGTAATCTCATATTAACAGCCAGGTCTCTAGACAAACTT
  TATAACTTTGCTGATTGCTCTGGACTCCACCTGATATTTGCTCTAAATGCACTGCGTCGTAATCCCAATA
  ACTCCTGGAACAGTTCTAGTGCCCTGAGTCTGTTGAAGTACAGCGCCAGCAAAAAGTACAACATTTCTTG
  GGAACTGGGTAATGAGCCAAATAACTATCGGACCATGCATGGCCGGGCAGTAAATGGCAGCCAGTTGGGA
  AAGGATTACATCCAGCTGAAGAGCCTGTTGCAGCCCATCCGGATTTATTCCAGAGCCAGCTTATATGGCC
  CTAATATTGGGCGGCCGAGGAAGAATGTCATCGCCCTCCTAGATGGATTCATGAAGGTGGCAGGAAGTAC
  AGTAGATGCAGTTACCTGGCAACATTGCTACATTGATGGCCGGGTGGTCAAGGTGATGGACTTCCTGAAA
  ACTCGCCTGTTAGACACACTCTCTGACCAGATTAGGAAAATTCAGAAAGTGGTTAATACATACACTCCAG
  GAAAGAAGATTTGGCTTGAAGGTGTGGTGACCACCTCAGCTGGAGGCACAAACAATCTATCCGATTCCTA
  TGCTGCAGGATTCTTATGGTTGAACACTTTAGGAATGCTGGCCAATCAGGGCATTGATGTCGTGATACGG
  CACTCATTTTTTGACCATGGATACAATCACCTCGTGGACCAGAATTTTAACCCATTACCAGACTACTGGC
  TCTCTCTCCTCTACAAGCGCCTGATCGGCCCCAAAGTCTTGGCTGTGCATGTGGCTGGGCTCCAGCGGAA
  GCCACGGCCTGGCCGAGTGATCCGGGACAAACTAAGGATTTATGCTCACTGCACAAACCACCACAACCAC
  AACTACGTTCGTGGGTCCATTACACTTTTTATCATCAACTTGCATCGATCAAGAAAGAAAATCAAGCTGG
  CTGGGACTCTCAGAGACAAGCTGGTTCACCAGTACCTGCTGCAGCCCTATGGGCAGGAGGGCCTAAAGTC
  CAAGTCAGTGCAACTGAATGGCCAGCCCTTAGTGATGGTGGACGACGGGACCCTCCCAGAATTGAAGCCC
  CGCCCCCTTCGGGCCGGCCGGACATTGGTCATCCCTCCAGTCACCATGGGCTTTTATGTGGTCAAGAATG
  TCAATGCTTTGGCCTGCCGCTACCGATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_021828
• ORF Size: 1779 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_021828.4, NP_068600.4
• RefSeq Size: 4349
• RefSeq ORF: 1779
• Locus ID: 60495
• Protein Pathways: Glycosaminoglycan degradation, Metabolic pathways
• Gene Summary: This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.