UBA6 (NM_018227) Human Untagged Clone

CAT#: SC318471

UBA6 (untagged)-Human ubiquitin-like modifier activating enzyme 6 (UBA6)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBA6
• Synonyms: E1-L2; MOP-4; UBE1L2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018227, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAGGATCCGAGCCTGTGGCCGCCCATCAGGGGGAAGAGGCGTCCTGTTCTTCCTGGGGGACTGGCA
  GCACAAATAAAAATTTGCCCATTATGTCAACAGCATCTGTGGAAATCGATGATGCATTGTATAGTCGACA
  GAGGTACGTTCTTGGAGACACAGCAATGCAGAAGATGGCCAAGTCCCATGTTTTCTTAAGTGGGATGGGT
  GGTCTTGGTTTGGAAATTGCAAAGAATCTTGTTCTTGCAGGGATTAAGGCAGTTACAATTCATGATACAG
  AAAAATGCCAAGCATGGGATCTAGGAACCAACTTCTTTCTCAGTGAAGATGATGTTGTTAATAAGAGAAA
  CAGGGCTGAAGCTGTACTTAAACATATTGCAGAACTAAATCCATACGTTCATGTCACATCATCTTCTGTT
  CCTTTCAATGAGACCACAGATCTCTCCTTTTTAGATAAATACCAGTGTGTAGTATTGACTGAGATGAAAC
  TTCCATTGCAGAAGAAGATCAATGACTTTTGCCGTTCTCAGTGCCCTCCAATTAAGTTTATCAGTGCAGA
  TGTACATGGAATTTGGTCAAGGTTATTTTGTGATTTCGGTGATGAATTTGAAGTTTTAGATACAACAGGA
  GAAGAACCAAAAGAAATTTTCATTTCAAACATAACGCAAGCAAATCCTGGCATTGTTACTTGCCTTGAAA
  ATCATCCTCACAAACTGGAGACAGGACAATTCCTAACATTTCGAGAAATTAATGGAATGACAGGTTTAAA
  TGGATCTATACAACAAATAACGGTGATATCGCCATTTTCTTTTAGTATTGGTGACACCACAGAACTGGAA
  CCATATTTACATGGAGGCATAGCTGTCCAAGTTAAGACTCCTAAAACAGTTTTTTTTGAATCACTGGAGA
  GGCAGTTAAAACATCCAAAGTGCCTTATTGTGGATTTTAGCAACCCTGAGGCACCTTTAGAGATTCACAC
  AGCTATGCTTGCCTTGGACCAGTTTCAGGAGAAATACAGTCGCAAGCCAAATGTTGGATGCCAACAAGAT
  TCAGAAGAACTGTTGAAACTAGCAACATCTATAAGTGAAACCTTGGAAGAGAAGCCTGATGTAAATGCTG
  ACATTGTGCATTGGCTCTCTTGGACTGCCCAAGGCTTTTTATCTCCACTTGCTGCAGCAGTAGGAGGTGT
  TGCCAGCCAAGAAGTATTGAAAGCTGTAACAGGAAAATTTTCTCCTTTGTGCCAGTGGTTATATCTTGAA
  GCAGCAGATATTGTTGAATCACTAGGCAAACCTGAATGTGAAGAATTTCTCCCACGAGGAGATAGATATG
  ATGCCTTAAGAGCTTGCATTGGAGACACTTTGTGTCAGAAACTGCAAAATTTAAACATCTTCTTAGTAGG
  GTGTGGAGCCATAGGCTGTGAAATGTTGAAAAATTTTGCTTTACTTGGTGTTGGCACAAGCAAAGAGAAA
  GGAATGATTACAGTTACAGATCCTGACTTGATAGAGAAATCCAACTTAAATAGACAGTTCCTATTTCGTC
  CTCATCACATACAGAAACCTAAAAGCTACACTGCTGCTGATGCTACTCTGAAAATAAATTCTCAAATAAA
  GATAGATGCACACCTGAACAAAGTATGTCCAACCACTGAGACCATTTACAATGATGAGTTCTATACTAAA
  CAAGATGTAATTATTACAGCATTAGATAATGTGGAAGCCAGGAGATACGTAGACAGTCGTTGCTTAGCAA
  ATCTAAGGCCTCTTTTAGATTCTGGAACAATGGGCACTAAGGGACACACTGAAGTTATTGTACCGCATTT
  GACTGAGTCTTACAATAGTCATCGGGATCCCCCAGAAGAGGAAATACCATTTTGTACTCTAAAATCCTTT
  CCAGCTGCTATTGAACATACCATACAGTGGGCAAGAGATAAGTTTGAAAGTTCCTTTTCCCACAAACCTT
  CATTGTTTAACAAATTTTGGCAAACCTATTCATCTGCAGAAGAAGTCTTACAGAAGATACAGAGTGGACA
  CAGTTTAGAAGGCTGTTTTCAAGTTATAAAGTTACTTAGCAGAAGACCTAGAAATTGGTCCCAGTGTGTA
  GAATTAGCAAGATTAAAGTTTGAAAAATATTTTAACCATAAGGCTCTTCAGCTTCTTCACTGTTTCCCTC
  TGGACATACGATTAAAAGATGGCAGTTTATTTTGGCAGTCACCAAAGAGGCCACCCTCTCCAATAAAATT
  TGATTTAAATGAGCCTTTGCACCTCAGTTTCCTTCAGAATGCTGCAAAACTATATGCTACAGTATATTGT
  ATTCCATTTGCAGAAGAGGACTTATCAGCAGATGCCCTCTTGAATATTCTTTCAGAAGTAAAGATTCAGG
  AATTCAAGCCTTCCAATAAGGTTGTTCAAACAGATGAAACTGCAAGGAAACCAGACCATGTTCCTATTAG
  CAGTGAAGATGAGAGGAATGCAATTTTCCAACTAGAAAAGGCTATTTTATCTAATGAAGCCACCAAAAGT
  GACCTTCAGATGGCAGTGCTTTCATTTGAAAAAGATGATGATCATAATGGACACATAGATTTCATCACAG
  CTGCATCAAATCTTCGTGCCAAAATGTACAGCATTGAACCAGCTGACCGTTTCAAAACAAAGCGCATAGC
  TGGTAAAATTATACCTGCTATAGCAACAACCACTGCTACAGTTTCTGGCTTGGTTGCCTTGGAGATGATC
  AAAGTAACTGGTGGCTATCCATTTGAAGCTTACAAAAATTGTTTTCTTAACTTAGCCATTCCAATTGTAG
  TATTTACAGAGACAACTGAAGTAAGGAAAACTAAAATCAGAAATGGAATATCATTTACAATTTGGGATCG
  ATGGACCGTACATGGAAAAGAAGATTTCACCCTCTTGGATTTCATAAATGCAGTCAAAGAGAAGTATGGA
  ATTGAGCCAACAATGGTGGTACAGGGAGTCAAAATGCTTTATGTTCCTGTAATGCCTGGTCATGCAAAAA
  GATTGAAGTTAACAATGCATAAACTTGTAAAACCTACTACTGAAAAGAAATATGTGGATCTTACTGTGTC
  ATTTGCTCCAGACATTGATGGAGATGAAGATTTGCCGGGACCTCCAGTAAGATACTACTTCAGTCATGAC
  ACTGATTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_018227
• ORF Size: 3159 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018227.5, NP_060697.4
• RefSeq Size: 6462
• RefSeq ORF: 3159
• Locus ID: 55236
• Domains: UBACT, ThiF
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]). [supplied by OMIM, Mar 2008]