RPS6KC1 (NM_012424) Human Untagged Clone

CAT#: SC318476

RPS6KC1 (untagged)-Human ribosomal protein S6 kinase, 52kDa, polypeptide 1 (RPS6KC1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RPS6KC1
• Synonyms: humS6PKh1; RPK118; RSKL1; S6K-delta-1; S6PKh1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012424, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACCTCTTACCGGGAGCGGAGTGCCGACCTGGCCCGTTTCTACACTGTCACCGAGCCCCAGCGACACC
  CGAGGGGCTACACAGTATATAAGGTCACCGCCCGGGTTGTTTCACGAAGAAATCCAGAGGATGTCCAGGA
  GATAATTGTATGGAAGAGATACAGTGATTTTAAGAAACTACACAAAGAACTATGGCAAATTCACAAAAAC
  TTATTCCGACATTCAGAGTTGTTTCCTCCATTTGCTAAAGGAATAGTGTTTGGGCGATTTGATGAAACTG
  TTATCGAAGAGAGAAGACAATGTGCTGAAGACCTGCTACAGTTCTCTGCCAATATTCCTGCTCTTTACAA
  TAGTAAACAGCTTGAAGACTTTTTCAAGGGTGGAATAATTAATGATAGTTCTGAATTAATTGGTCCTGCT
  GAAGCTCACTCAGATTCCCTCATTGATACCTTTCCTGAGTGTAGTACGGAAGGCTTCTCCAGTGACAGTG
  ATCTGGTATCTCTTACTGTTGATGTGGATTCTCTTGCTGAGTTAGATGATGGAATGGCTTCCAATCAAAA
  TTCTCCCATTAGAACTTTTGGTCTCAATCTTTCTTCGGATTCTTCAGCACTAGGGGCTGTTGCTTCTGAC
  AGTGAACAGAGCAAAACAGAAGAAGAACGGGAAAGTCGTAGCCTCTTTCCTGGCAGTTTAAAGCCGAAGC
  TTGGCAAGAGAGATTATTTGGAGAAAGCAGGAGAATTAATAAAGCTGGCTTTAAAAAAGGAAGAAGAAGA
  CGACTATGAAGCTGCTTCTGATTTTTATAGGAAGGGAGTTGATTTACTCCTAGAAGGTGTTCAAGGAGAG
  TCAAGCCCTACCCGTCGAGAAGCTGTGAAGAGAAGAACAGCCGAGTACCTCATGCGGGCAGAAAGTATCT
  CTAGTCTTTATGGGAAACCTCAGCTTGATGATGTATCTCAGCCTCCAGGATCACTAAGTTCAAGGCCCCT
  TTGGAACCTAAGGAGCCCTGCCGAGGAGCTGAAGGCCTTCAGAGTCCTTGGGGTGATTGACAAGGTTTTA
  CTTGTAATGGACACAAGGACAGAACAGACTTTCATTTTAAAAGGTCTAAGGAAAAGCAGTGAATACAGCA
  GGAACAGAAAGACCATCATCCCCCGCTGTGTGCCCAACATGGTGTGTCTGCATAAGTACATCATCTCTGA
  GGAGTCAGTATTTCTTGTGCTGCAGCATGCGGAAGGTGGCAAACTGTGGTCATATATCAGTAAATTTCTA
  AACAGAAGTCCTGAAGAAAGCTTTGACATCAAGGAAGTGAAAAAACCTACACTTGCAAAAGTTCACCTGC
  AGCAGCCAACTTCTAGTCCTCAGGACAGCAGTAGCTTTGAATCCAGAGGAAGTGATGGTGGAAGCATGCT
  TAAAGCTCTGCCTTTGAAGAGTAGTCTTACTCCAAGTTCTCAAGATGACAGCAACCAGGAAGATGATGGC
  CAAGATAGCTCTCCAAAGTGGCCAGATTCTGGTTCAAGTTCAGAAGAAGAATGTACTACTAGTTATTTAA
  CATTATGCAATGAATATGGGCAAGAAAAGATTGAACCAGGGTCTTTGAATGAGGAGCCCTTCATGAAGAC
  TGAAGGGAATGGTGTTGATACAAAAGCTATTAAAAGCTTCCCAGCACACCTTGCTGCTGACAGTGACAGC
  CCCAGCACACAGCTGAGAGCTCACGAGCTGAAGTTCTTCCCCAACGATGACCCAGAAGCAGTTAGTTCTC
  CAAGAACATCAGATTCCCTCAGTAGATCAAAAAATAGCCCCATGGAATTCTTTAGGATAGACAGTAAGGA
  TAGCGCAAGTGAACTCCTGGGACTTGACTTTGGAGAAAAATTGTATAGTCTAAAATCAGAACCTTTGAAA
  CCATTCTTTACTCTTCCAGATGGAGACAGTGCTTCTAGGAGTTTTAATACTAGTGAAAGCAAGGTAGAGT
  TTAAAGCTCAGGACACCATTAGCAGGGGCTCAGATGACTCAGTGCCAGTTATTTCATTTAAAGATGCTGC
  TTTTGATGATGTCAGTGGTACTGATGAAGGAAGACCTGATCTTCTTGTAAATTTACCTGGTGAATTGGAG
  TCAACAAGAGAAGCTGCAGCAATGGGACCTACTAAGTTTACACAAACTAATATAGGGATAATAGAAAATA
  AACTCTTGGAAGCCCCTGATGTTTTATGCCTCAGGCTTAGTACTGAACAATGCCAAGCACATGAGGAGAA
  AGGCATAGAGGAACTGAGTGATCCCTCTGGGCCCAAATCCTATAGTATAACAGAGAAACACTATGCACAG
  GAGGATCCCAGGATGTTATTTGTAGCAGCTGTTGATCATAGTAGTTCAGGAGATATGTCTTTGTTACCCA
  GCTCAGATCCTAAGTTTCAAGGACTTGGAGTGGTTGAGTCAGCAGTAACTGCAAACAACACAGAAGAAAG
  CTTATTCCGTATTTGTAGTCCACTCTCAGGTGCTAATGAATATATTGCAAGCACAGACACTTTAAAAACA
  GAAGAAGTATTGCTGTTTACAGATCAGACTGATGATTTGGCTAAAGAGGAACCAACTTCTTTATTCCAGA
  GAGACTCTGAGACTAAGGGTGAAAGTGGTTTAGTGCTAGAAGGAGACAAGGAAATACATCAGATTTTTGA
  GGACCTTGATAAAAAATTAGCACTAGCCTCCAGGTTTTACATCCCAGAGGGCTGCATTCAAAGATGGGCA
  GCTGAAATGGTGGTAGCCCTTGATGCTTTACATAGAGAGGGAATTGTGTGCCGCGATTTGAACCCAAACA
  ACATCTTATTGAATGATAGAGGACACATTCAGCTAACGTATTTTAGCAGGTGGAGTGAGGTTGAAGATTC
  CTGTGACAGCGATGCCATAGAGAGAATGTACTGTGCCCCAGAGGTTGGAGCAATCACTGAAGAAACTGAA
  GCCTGTGATTGGTGGAGTTTGGGTGCTGTCCTCTTTGAACTTCTCACTGGCAAGACTCTGGTTGAATGCC
  ATCCAGCAGGAATAAATACTCACACTACTTTGAACATGCCAGAATGTGTCTCTGAAGAGGCTCGCTCACT
  CATTCAACAGCTCTTGCAGTTCAATCCTCTGGAACGACTTGGTGCTGGAGTTGCTGGTGTTGAAGATATC
  AAATCTCATCCATTTTTTACCCCTGTGGATTGGGCAGAACTGATGAGATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_012424
• ORF Size: 3201 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012424.4, NP_036556.2
• RefSeq Size: 4219
• RefSeq ORF: 3201
• Locus ID: 26750
• Domains: pkinase, PX, S_TKc, MIT
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (1) encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.