CNGB1 (NM_001297) Human Untagged Clone

CAT#: SC318568

CNGB1 (untagged)-Human cyclic nucleotide gated channel beta 1 (CNGB1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CNGB1
• Synonyms: CNCG2; CNCG3L; CNCG4; CNG4; CNGB1B; GAR1; GARP; GARP2; RCNC2; RCNCb; RCNCbeta; RP45
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001297, the custom clone sequence may differ by one or more nucleotides
  ATGTTGGGCTGGGTCCAGAGGGTGCTGCCTCAGCCCCCAGGGACCCCTCGGAAGACCAAG
  ATGCAGGAGGAAGAGGAAGTGGAACCAGAGCCAGAGATGGAGGCGGAGGTGGAACCAGAA
  CCGAATCCTGAGGAGGCCGAGACAGAGTCCGAGTCCATGCCCCCCGAAGAGTCATTCAAG
  GAGGAGGAAGTGGCTGTGGCAGACCCAAGCCCTCAGGAGACCAAGGAGGCTGCCCTTACT
  TCCACCATATCCCTCCGGGCCCAGGGCGCTGAGATTTCTGAAATGAATAGTCCCAGCCGC
  AGGGTACTGACCTGGCTCATGAAGGGCGTAGAGAAGGTGATCCCGCAGCCTGTTCACAGC
  ATCACGGAGGACCCGGCTCAGATCCTGGGGCATGGCAGCACTGGGGACACAGGGTGCACA
  GATGAACCCAATGAGGCCCTTGAGGCCCAAGACACTAGGCCTGGGCTGCGGCTGCTTCTG
  TGGCTGGAGCAGAATCTGGAAAGAGTGCTTCCTCAGCCCCCCAAATCCTCTGAGGTCTGG
  AGAGATGAGCCTGCAGTTGCTACAGGTGCTGCCTCAGACCCAGCGCCTCCAGGACGCCCC
  CAGGAAATGGGGCCCAAGCTGCAGGCCCGGGAGACCCCCTCCCTGCCCACACCCATCCCC
  CTGCAGCCCAAGGAGGAACCCAAGGAGGCACCAGCTCCAGAGCCCCAGCCCGGCTCCCAG
  GCCCAGACCTCCTCCCTGCCACCAACCAGGGACCCTGCCAGGCTGGTGGCATGGGTCCTG
  CACAGGCTGGAGATGGCCTTGCCGCAGCCAGTGCTACATGGGAAAATAGGGGAACAGGAG
  CCTGACTCCCCTGGGATATGTGATGTGCAGACCATCAGCATCCTTCCTGGAGGACAAGTG
  GAGCCTGACCTTGTCCTAGAGGAGGTTGAACCGCCCTGGGAGGATGCCCACCAGGATGTC
  AGTACCAGCCCACAGGGTACAGAGGTGGTTCCAGCTTATGAAGAAGAGAACAAAGCTGTG
  GAGAAGATGCCCAGAGAGCTGTCCCGGATTGAAGAGGAGAAAGAAGATGAGGAGGAGGAA
  GAGGAAGAGGAGGAGGAGGAGGAAGAGGAGGAGGTGACTGAGGTGCTGCTGGATAGCTGT
  GTGGTGTCGCAGGTGGGCGTGGGCCAGAGTGAAGAAGACGGGACCCGGCCCCAGAGCACT
  TCAGATCAGAAGCTGTGGGAGGAAGTTGGGGAGGAGGCCAAGAAGGAGGCTGAAGAGAAG
  GCCAAGGAGGAGGCCGAGGAGGTGGCTGAAGAGGAGGCTGAAAAGGAGCCCCAGGACTGG
  GCGGAGACCAAGGAGGAGCCTGAGGCTGAGGCCGAGGCTGCCAGTTCAGGAGTGCCTGCC
  ACGAAACAGCACCCAGAAGTGCAGGTGGAAGATACTGATGCTGATAGCTGCCCCCTCATG
  GCAGAAGAGAATCCACCCTCAACCGTGTTGCCGCCACCGTCTCCTGCCAAATCAGACACC
  CTTATAGTCCCAAGCTCAGCCTCGGGGACACACAGGAAGAAGCTGCCCTCTGAGGATGAT
  GAGGCTGAAGAGCTCAAGGCGTTGTCACCAGCAGAGTCCCCAGTGGTTGCCTGGTCTGAC
  CCCACCACCCCGAAGGACACTGATGGCCAGGACCGTGCGGCCTCCACGGCCAGCACAAAT
  AGCGCCATCATCAACGACCGGCTCCAGGAGCTGGTGAAGCTCTTCAAGGAGCGGACAGAG
  AAAGTGAAGGAGAAACTCATTGACCCTGACGTCACCTCTGATGAGGAGAGCCCCAAGCCC
  TCCCCAGCCAAGAAAGCCCCAGAGCCAGCTCCAGACACAAAGCCCGCTGAAGCCGAGCCA
  GTGGAAGAGGAGCACTATTGCGACATGCTCTGCTGCAAGTTCAAACACCGCCCCTGGAAG
  AAGTACCAGTTTCCCCAGAGCATTGACCCGCTGACCAACCTGATGTATGTCCTATGGCTG
  TTCTTCGTGGTGATGGCCTGGAATTGGAACTGTTGGCTGATTCCCGTGCGCTGGGCCTTC
  CCCTACCAGACCCCGGACAACATCCACCACTGGCTGCTGATGGATTACCTATGCGACCTC
  ATCTACTTCCTGGACATCACCGTGTTCCAGACACGCCTGCAGTTTGTCAGAGGCGGGGAC
  ATCATTACGGACAAAAAGGACATGCGAAATAACTACCTGAAGTCTCGCCGCTTCAAGATG
  GACCTGCTCAGCCTCCTGCCCTTGGATTTTCTCTATTTGAAAGTCGGTGTGAACCCCCTC
  CTCCGCCTGCCCCGCTGTTTAAAGTACATGGCCTTCTTCGAGTTTAACAGCCGCCTGGAA
  TCCATCCTCAGCAAAGCCTACGTGTACAGGGTCATCAGGACCACAGCCTACCTTCTCTAC
  AGCCTGCATTTGAATTCCTGTCTTTATTACTGGGCATCGGCCTATCAGGGCCTCGGCTCC
  ACTCACTGGGTTTACGATGGCGTGGGAAACAGTTATATTCGCTGTTACTACTTTGCTGTG
  AAGACCCTCATCACCATCGGGGGGCTGCCTGACCCCAAGACACTCTTTGAAATTGTCTTC
  CAGCTGCTGAATTATTTCACGGGCGTCTTTGCTTTCTCTGTGATGATCGGACAGATGAGA
  GATGTGGTAGGGGCCGCCACCGCCGGACAGACCTACTACCGCAGCTGCATGGACAGCACG
  GTGAAGTACATGAATTTCTACAAGATCCCCAAGTCCGTGCAGAACCGCGTCAAGACCTGG
  TACGAGTACACCTGGCACTCGCAAGGCATGCTGGATGAGTCAGAGCTGATGGTGCAGCTT
  CCAGACAAGATGCGGCTGGACCTCGCCATCGACGTGAACTACAACATCGTTAGCAAAGTC
  GCACTCTTTCAGGGCTGTGACCGGCAGATGATCTTTGACATGCTGAAGAGGCTTCGCTCT
  GTTGTCTACCTGCCCAACGACTATGTGTGCAAGAAGGGGGAGATCGGCCGTGAGATGTAC
  ATCATCCAGGCAGGGCAAGTGCAGGTCTTGGGCGGCCCTGATGGGAAATCTGTGCTGGTG
  ACGCTGAAAGCTGGATCTGTGTTTGGAGAAATAAGCTTGCTGGCTGTTGGGGGCGGGAAC
  CGGCGCACGGCCAACGTGGTGGCGCACGGGTTTACCAACCTCTTCATCCTGGATAAGAAG
  GACCTGAATGAGATTTTGGTGCATTATCCTGAGTCTCAGAAGTTACTCCGGAAGAAAGCC
  AGGCGCATGCTGAGAAGCAACAATAAGCCCAAGGAGGAGAAGAGCGTGCTGATCCTTCCA
  CCCCGGGCGGGCACCCCAAAGCTCTTCAACGCTGCCCTCGCTATGACAGGAAAGATGGGT
  GGCAAGGGGGCAAAAGGCGGCAAACTTGCTCACCTCCGGGCCCGGCTCAAAGAACTGGCC
  GCGCTGGAGGCGGCTGCAAAGCAGCAAGAGTTGGTGGAACAGGCCAAGAGCTCGCAAGAC
  GTCAAGGGAGAGGAAGGCTCCGCCGCCCCAGACCAGCACACGCACCCAAAGGAGGCCGCC
  ACCGACCCACCCGCGCCCCGGACGCCCCCCGAGCCCCCGGGGTCTCCACCGAGCTCTCCA
  CCGCCTGCCTCCCTTGGGAGGCCGGAGGGAGAGGAGGAGGGGCCGGCCGAGCCCGAAGAG
  CACTCGGTGAGGATCTGCATGAGCCCGGGCCCGGAGCCGGGAGAGCAGATCCTGTCGGTG
  AAGATGCCGGAGGAAAGGGAGGAGAAGGCGGAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001297
• Insert Size: 5663 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001297.3, NP_001288.3
• RefSeq Size: 5663 bp
• RefSeq ORF: 3756 bp
• Locus ID: 1258
• Cytogenetics: 16q21
• Protein Families: Druggable Genome, Ion Channels: Cyclic nucleotide gated
• Protein Pathways: Olfactory transduction
• Gene Summary: 'In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).