WIBG (PYM1) (NM_032345) Human Untagged Clone

CAT#: SC319172

WIBG (untagged)-Human within bgcn homolog (Drosophila) (WIBG), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PYM1
• Synonyms: PYM; WIBG
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_032345.1 GGGCCCAGCCCGAGGAGGCACTCAGGGTTAGGAGGTCTGGGCGAGAAGCAACTAGGGCCC
  TCATCACTTCGCCGCCGAATCCCCGGCGCCGCCCAGCGGGGCAGAGCCAGGCCAGGGCCG
  CCCGCCCAACCTGGTCCGCTGCCTCTTCGGCCATGGAAGCTGCCGGCAGCCCTGCGGCTA
  CGGAGACAGGCAAGTATATCGCGTCAACACAGCGACCTGACGGGACCTGGCGCAAGCAGC
  GGAGGGTGAAAGAAGGATATGTGCCCCAGGAGGAGGTCCCAGTATATGAAAACAAGTATG
  TGAAGTTTTTCAAGAGTAAACCAGAGTTGCCCCCAGGGCTAAGCCCTGAGGCCACTGCTC
  CTGTCACCCCATCCAGGCCTGAAGGTGGTGAACCAGGCCTCTCCAAGACAGCCAAACGTA
  ACCTGAAGCGAAAGGAGAAGAGGCGGCAGCAGCAAGAGAAAGGAGAGGCAGAGGCCTTGA
  GCAGGACTCTTGATAAGGTGTCCCTGGAAGAGACAGCCCAACTCCCCAGTGCTCCACAGG
  GCTCTCGGGCAGCCCCCACAGCTGCATCTGACCAGCCTGACTCAGCTGCCACCACTGAGA
  AAGCCAAGAAGATAAAGAACCTAAAGAAGAAACTCCGGCAGGTGGAAGAGCTGCAGCAGC
  GGATCCAGGCTGGGGAAGTCAGCCAGCCCAGCAAAGAGCAGCTAGAAAAGCTAGCAAGGA
  GGAGGGCGCTAGAAGAGGAGTTAGAGGACTTGGAGTTAGGCCTCTGAGGCCTTTGGGGAA
  TAGGGAATGGACTGCAGAACAAACCGTGGGGCTCTCTGGGGTCTGGGGGAATACGGGCAA
  CAGCAGTCAGGAGGGGTACCCCCCATACTGGCTTCCACCTCCTGCGGCCCAGCTCTGTCC
  TCCAGAGCCTAGCGTCTCCCTCAATCCTTCCCTTTTCTTCCCAACTTCTACTTTTTGGAC
  TTTCCCCCTCCCATTCCCAGTGTTCAAAATCTCAGTGACTACCCCAGGTACCTTTGCTGC
  TGATTTGGGTGTCTTGTTTAAAAGAAAATCAGGTGGGTGGGAATCTCTTGGAGAACTGAG
  GCTGAGGGTAGAGGGAGTATGCCCAAGTCTTGGAGTCTTGGTTCCTGTTCGCGGTGTTTA
  TGGGTTATTTCCCTCTCCATCCCTCATTTTTTTTTTTTTTTTAAAAAAAGCAAAAATGAG
  AATAAACACAAGTAGACATGTCAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032345.1 unedited
  GGCCTTATGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGGGCCCAGCCC
  GAGGAGGCACTCAGGGTTAGGAGGTCTGGGCGAGAAGCAACTAGGGCCCTCATCACTTCG
  CCGCCGAATCCCCGGCGCCGCCCAGCGGGGCAGAGCCAGGCCAGGGCCGCCCGCCCAACC
  TGGTCCGCTGCCTCTTCGGCCATGGAAGCTGCCGGCAGCCCTGCGGCTACGGAGACAGGC
  AAGTATATCGCGTCAACACAGCGACCTGACGGGACCTGGCGCAAGCAGCGGAGGGTGAAA
  GAAGGATATGTGCCCCAGGAGGAGGTCCCAGTATATGAAAACAAGTATGTGAAGTTTTTC
  AAGAGTAAACCAGAGTTGCCCCCAGGGCTAAGCCCTGAGGCCACTGCTCCTGTCACCCCA
  TCCAGGCCTGAAGGTGGTGAACCAGGCCTCTCCAAGACAGCCAAACGTAACCTGAAGCGA
  AAGGAGAAGAGGCGGCAGCAGCAAGAGAAAGGAGAGGCAGAGGCCTTGAGCAGGACTCTT
  GATAAGGTGTCCCTGGAAGAGACAGCCCAACTCCCCAGTGCTCCACAGGGCTCTCGGGCA
  GCCCCCACAGCTGCATCTGACCAGCCTGACTCAGCTGCCACCACTGAGAAAGCCAAGAAG
  ATAAAGAACCTAAAGAAGAAACTCCGGCAGGTGGAAGAGCTGCAGCAGCGGATCCAGGCT
  GGGGAAGTCAGCCAGCCCAGCAAGAGCAGCTAGAAAAGCTAGCAAGAGGAGGGCGCTAGA
  GAGAGTTAGAGGACTTGGAGTTAGCCTCTGAGCCCTTTGGGGAATAGGGAATGGACTGCA
  GAACAAAACCGTGGGGGCTCTCTGGGGTCTGGGGGATACGGCACAGCAGTCAGAGGGTAC
  CCCCCATAACTGGCCTCACTCTGCGTCAGGCTCTTGTTCTCATGAAGCTAGGCGTTCTTC
  CCCTCCTATCCTTGCT
• Restriction Sites: Please inquire
• ACCN: NM_032345
• ORF Size: 615 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032345.1, NP_115721.1
• RefSeq Size: 1240
• RefSeq ORF: 615
• Locus ID: 84305
• Gene Summary: Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA; the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).