STUB1 (NM_005861) Human Untagged Clone

CAT#: SC319337

STUB1 (untagged)-Human STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase (STUB1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STUB1
• Synonyms: CHIP; HSPABP2; NY-CO-7; SCA48; SCAR16; SDCCAG7; UBOX1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005861 edited
  CACGAGGCTGCGGGGCTCCGGCTGCGGGCGCTGGGCCGCGAGGCGCGGAGCTTGGGAGCG
  GAGCCCAGGCCGTGCCGCGCGGCGCCATGAAGGGCAAGGAGGAGAAGGAGGGCGGCGCAC
  GGCTGGGCGCTGGCGGCGGAAGCCCCGAGAAGAGCCCGAGCGCGCAGGAGCTCAAGGAGC
  AGGGCAATCGTCTGTTCGTGGGCCGAAAGTACCCGGAGGCGGCGGCCTGCTACGGCCGCG
  CGATCACCCGGAACCCGCTGGTGGCCGTGTATTACACCAACCGGGCCTTGTGCTACCTGA
  AGATGCAGCAGCACGAGCAGGCCCTGGCCGACTGCCGGCGCGCCCTGGAGCTGGACGGGC
  AGTCTGTGAAGGCGCACTTCTTCCTGGGGCAGTGCCAGCTGGAGATGGAGAGCTATGATG
  AGGCCATCGCCAATCTGCAGCGAGCTTACAGCCTGGCCAAGGAGCAGCGGCTGAACTTCG
  GGGACGACATCCCCAGCGCTCTTCGAATCGCGAAGAAGAAGCGCTGGAACAGCATTGAGG
  AGCGGCGCATCCACCAGGAGAGCGAGCTGCACTCCTACCTCTCCAGGCTCATTGCCGCGG
  AGCGTGAGAGGGAGCTGGAAGAGTGCCAGCGAAACCACGAGGGTGATGAGGACGACAGCC
  ACGTCCGGGCCCAGCAGGCCTGCATTGAGGCCAAGCACGACAAGTACATGGCGGACATGG
  ACGAGCTTTTTTCTCAGGTGGATGAGAAGAGGAAGAAGCGAGACATCCCCGACTACCTGT
  GTGGCAAGATCAGCTTTGAGCTGATGCGGGAGCCGTGCATCACGCCCAGTGGCATCACCT
  ACGACCGCAAGGACATCGAGGAGCACCTGCAGCGTGTGGGTCATTTTGACCCCGTGACCC
  GGAGCCCCCTGACCCAGGAACAGCTCATCCCCAACTTGGCTATGAAGGAGGTTATTGACG
  CATTCATCTCTGAGAATGGCTGGGTGGAGGACTACTGAGGTTCCCTGCCCTACCTGGCGT
  CCTGGTCCAGGGGAGCCCTGGGCAGAAGCCCCCGGCCCCTATACATAGTTTATGTTCCTG
  GCCACCCCGACCGCTTCCCCCAAGTTCTGCTGTTGGACTCTGGACTGTTTCCCCTCTCAG
  CATCGCTTTTGCTGGGCCGTGATCGTCCCCCTTTGTGGGCTGGAAAAGCAGGTGAGGGTG
  GGCTGGGCTGAGGCCATTGCCGCCACTATCTGTGTAATAAAATCCGTGAGCACGAGGTGG
  GACGTGCTGGTGTGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  A
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005861.2 unedited
  GAGCATTGTATACGACTCCTATAGGGCGGCCGGGTAATTCGGCACGAGGCTGCGGGGCTC
  CGGCTGCGGGCGCTGGGCCGCGAGGCGCGGAGCTTGGGAGCGGAGCCCAGGCCGTGCCGC
  GCGGCGCCATGAAGGGCAAGGAGGAGAAGGAGGGCGGCGCACGGCTGGGCGCTGGCGGCG
  GAAGCCCCGAGAAGAGCCCGAGCGCGCAGGAGCTCAAGGAGCAGGGCAATCGTCTGTTCG
  TGGGCCGAAAGTACCCGGAGGCGGCGGCCTGCTACGGCCGCGCGATCACCCGGAACCCGC
  TGGTGGCCGTGTATTACACCAACCGGGCCTTGTGCTGCCGGAAGATGCAGCAGCACGAGC
  AGGCCCTGGCCGACTGCCGGCGCGCCCTGGAGCTGGACGGGCAGTCTGTGAAGGCGCACT
  TCTTCCTGGGGCAGTGCCAGCTGGAGATGGAGAGCTATGATGAGGCCATCGCCAATCTGC
  AGCGAGCTTACAGCCTGGCCAAGGAGCAGCGGCTGAACTTCGGGGACGACATCCCCAGCG
  CTCTTCGAATCGCGAAGAAGAGCGCTGGAACAGCATTGAGGAGCGGCGCATCCACCAGGA
  GAGCGAGCTGCACTCCTACCTCTCCAGGCTCATTGCCGCGGAGCGTGAGAGGGAGCTGGA
  AGAGTGCCAGCGAAACCACGAGGGTGATGAGGACGACAGCCACGTCCCGGGCCCAGCAGC
  CTGCATTGAGGCCAAGCACGACAAGTACATGGCGGACATGGACGAGCTTTTTTTCTCAGG
  TGGATGAGAGAGGAGAGCGAGACATCCCCGACTACCTGTGGTGGCAGATCAGCTTTGAGC
  TGATGCGGGAGCGTGCATCACGCCCAGTGGCATCACTACGAACCGCAGACATCGAAGGAG
  CACTGCAGCGTGTGGTCATTTGAACCGTGACTGGAGCCCCCTTGACCAGGAACAGCTCAT
  CCTAACTG
• Restriction Sites: Please inquire
• ACCN: NM_005861
• ORF Size: 912 bp
• Insert Size: 1300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005861.2, NP_005852.2
• RefSeq Size: 1646
• RefSeq ORF: 912
• Locus ID: 10273
• Domains: TPR, U-box
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2. [provided by RefSeq, Jun 2014]
  Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (a).