COPS6 (NM_006833) Human Untagged Clone

CAT#: SC319375

COPS6 (untagged)-Human COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) (COPS6)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COPS6
• Synonyms: CSN6; MOV34-34KD
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006833.4 GGAAAATGGCGGCGGCGGCGGCGGCGGCTGCAGCTACGAACGGGACCGGAGGAAGCAGCG
  GGATGGAGGTGGATGCAGCAGTAGTCCCCAGCGTGATGGCCTGCGGAGTGACTGGGAGTG
  TTTCCGTCGCTCTCCATCCCCTTGTCATTCTCAACATCTCAGACCACTGGATCCGCATGC
  GCTCCCAGGAGGGGCGGCCTGTGCAGGTGATTGGGGCTCTGATTGGCAAGCAGGAGGGCC
  GAAATATCGAGGTGATGAACTCCTTTGAGCTGCTGTCCCACACCGTGGAAGAGAAGATTA
  TCATTGACAAGGAATATTATTACACCAAGGAGGAGCAGTTTAAACAGGTGTTCAAGGAGC
  TGGAGTTTCTGGGTTGGTATACCACAGGGGGGCCACCTGACCCCTCGGACATCCACGTCC
  ATAAGCAGGTGTGTGAGATCATCGAGAGCCCCCTCTTTCTGAAGTTGAACCCTATGACCA
  AGCACACAGATCTTCCTGTCAGCGTTTTTGAGTCTGTCATTGATATAATCAATGGAGAGG
  CCACAATGCTGTTTGCTGAGCTGACCTACACTCTGGCCACAGAGGAAGCGGAACGCATTG
  GTGTAGACCACGTAGCCCGAATGACAGCAACAGGCAGTGGAGAGAACTCCACTGTGGCTG
  AACACCTGATAGCACAGCACAGCGCCATCAAGATGCTGCACAGCCGCGTCAAGCTCATCT
  TGGAGTACGTCAAGGCCTCTGAAGCGGGAGAGGTCCCCTTTAATCATGAGATCCTGCGGG
  AGGCCTATGCTCTGTGTCACTGTCTCCCGGTGCTCAGCACAGACAAGTTCAAGACAGATT
  TTTATGATCAATGCAACGACGTGGGGCTCATGGCCTACCTCGGCACCATCACCAAAACGT
  GCAACACCATGAACCAGTTTGTGAACAAGTTCAATGTCCTCTACGACCGACAAGGCATCG
  GCAGGAGAATGCGCGGGCTCTTTTTCTGATGAGGGTACTTGAAGGGCTGATGGACAGGGG
  TCAGGCAACTATCCCAAAGGGGAGGGCACTACACTTCCTTGAGAGAAACCGCTGTCATTA
  ATAAAAGGGGAGCAGCCCCTGAGCACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006833.4 unedited
  GGACCTTGTCATACGACTCCTATAGGGCGGCCGGGTAATTCGGCACGAGGGGAAAATGGC
  GGCGGCGGCGGCGGCGGCTGCAGCTACGAACGGGACCGGAGGAAGCAGCGGGATGGAGGT
  GGATGCAGCAGTAGTCCCCAGCGTGATGGCCTGCGGAGTGACTGGGAGTGTTTCCGTCGC
  TCTCCATCCCCTTGTCATTCTCAACATCTCAGACCACTGGATCCGCATGCGCTCCCAGGA
  GGGGCGGCCTGTGCAGGTGATTGGGGCTCTGATTGGCAAGCAGGAGGGCCGAAATATCGA
  GGTGATGAACTCCTTTGAGCTGCTGTCCCACACCGTGGAAGAGAAGATTATCATTGACAA
  GGAATATTATTACACCAAGGAGGAGCAGTTTAAACAGGTGTTCAAGGAGCTGGAGTTTCT
  GGGTTGGTATACCACAGGGGGGCCACCTGACCCCTCGGACATCCACGTCCATAAGCAGGT
  GTGTGAGATCATCGAGAGCCCCCTCTTTCTGAAGTTGAACCCTATGACCAAGCACACAGA
  TCTTCCTGTCAGCGTTTTTGAGTCTGTCATTGATATAATCAATGGAGAGGCCACAATGCT
  GTTTGCTGAGCTGACCTACACTCTGGCCACAGAGGAAGCGGAACGCATTGGTGTAGACCA
  CGTAGCCCGAATGACAGCAACAGGCAGTGGAGAGAACTCCACTGGTGGCTGACACCTGAT
  AGCACAGCACAGCGCCATCAAGATGCTGCACAGCCGCGTCAAGCTCATCTTGGAGTACGT
  CAAGGCCTCTGAGCGGGGAGGAGGTCCCCTTTAATCATGAGATCTGCGGGAGCCTTATGC
  TTCTGTTGTCACTTGTTCTCCGTGCTCAGCACAGAACAGTTCAAGAAAGATTTTTATGAT
  CATGCAACGACCGTGGGCTCATGGCTACCTGGCACCATACACAACGTGCAAA
• Restriction Sites: Please inquire
• ACCN: NM_006833
• ORF Size: 984 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006833.4, NP_006824.2
• RefSeq Size: 1441
• RefSeq ORF: 984
• Locus ID: 10980
• Domains: JAB_MPN
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Gene Summary: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]