GMPPB (NM_021971) Human Untagged Clone

CAT#: SC319413

GMPPB (untagged)-Human GDP-mannose pyrophosphorylase B (GMPPB), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GMPPB
• Synonyms: LGMDR19; MDDGA14; MDDGB14; MDDGC14
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021971.1 CTGTGTTGTGGCGGCCCTGGATCCGGCGTCAGGGCGACCGGGCGGACGAGGTGGAGCCAG
  AGTCTGTCAGGCGGGTTGGTGAAGGGCGCGGGGCCGGGCACGGCGTTGGGAGTGCGCGGC
  AGGGACCGGCCAGGCGGGCTGCAGGCACCTCAGAGCCCGGGACACCCCCTCAACGTCCGC
  AGGCGCGATGAAGGCACTGATCTTAGTGGGGGGCTATGGGACGCGGCTACGGCCGCTGAC
  GCTGAGCACCCCGAAGCCACTGGTGGACTTCTGCAATAAGCCCATCTTGCTGCACCAAGT
  GGAGGCGCTAGCCGCGGCAGGCGTGGACCACGTGATCCTGGCCGTGAGCTACATGTCGCA
  GGTGCTGGAGAAGGAAATGAAGGCACAGGAGCAGAGGCTGGGAATCCGAATCTCCATGTC
  CCATGAAGAGGAGCCTTTGGGGACAGCTGGGCCCCTGGCGCTGGCCCGTGACCTACTCTC
  TGAGACTGCAGACCCTTTCTTCGTCCTCAACAGTGACGTGATCTGCGATTTCCCCTTCCA
  AGCCATGGTGCAGTTCCACCGGCACCATGGCCAGGAGGGCTCCATCCTGGTGACCAAGGT
  GGAGGAACCCTCCAAGTACGGTGTGGTGGTGTGTGAGGCTGACACAGGCCGCATTCACCG
  GTTCGTGGAGAAGCCACAGGTGTTTGTGTCCAATAAGATCAACGCAGGCATGTACATCCT
  GAGCCCTGCAGTGCTGCGGCGCATCCAGCTGCAGCCTACGTCCATTGAGAAGGAGGTCTT
  CCCCATTATGGCCAAGGAGGGGCAGCTATATGCCATGGAGTTACAGGGCTTCTGGATGGA
  CATTGGGCAGCCCAAGGACTTCCTCACTGGCATGTGCCTCTTCCTGCAGTCACTGAGGCA
  GAAGCAGCCTGAGCGGCTGTGCTCAGGCCCTGGCATTGTGGGCAACGTGCTGGTGGACCC
  AAGTGCCCGCATCGGCCAGAACTGCAGCATTGGCCCCAATGTGAGCCTGGGACCTGGCGT
  GGTGGTCGAAGATGGTGTGTGTATCCGGCGGTGCACGGTGCTGCGGGATGCCCGGATCCG
  TTCCCATTCCTGGCTTGAGTCCTGCATTGTGGGCTGGCGCTGCCGCGTGGGTCAGTGGGT
  ACGCATGGAGAACGTGACAGTGCTGGGTGAGGACGTCATAGTTAATGATGAGCTCTACCT
  CAACGGAGCCAGCGTGCTGCCCCACAAGTCTATTGGCGAGTCAGTGCCAGAGCCTCGTAT
  CATCATGTGAGGGGATGCAGTGGGGCTGGCCGAGCCCCGGTTTTCCCATCAGCAAGGGGA
  GTGCTGGCCTGACACATCAGAAGACCCTGGACTTGTCATTATTTGTCTGGGGGGCACTGG
  GTGAAGCTGAAGCTGTTGGACACCTGCCTTCTCATGTGGACATCATCTGGCAGGATCCCT
  GCTGGGCACACCCCACAAACCCCACTCCCTCAAGAAGGGCCAGGGCCAGGGCTGTATGGA
  ATAATAATTTAATGCTCACTGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021971.1 unedited
  GGCTATTGTCATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCTGTGTTGTGG
  CGGCCCTGGATCCGGCGTCAGGGCGACCGGGCGGACGAGGTGGAGCCAGAGTCTGTCAGG
  CGGGTTGGTGAAGGGCGCGGGGCCGGGCACGGCGTTGGGAGTGCGCGGCAGGGACCGGCC
  AGGCGGGCTGCAGGCACCTCAGAGCCCGGGACACCCCCTCAACGTCCGCAGGCGCGATGA
  AGGCACTGATCTTAGTGGGGGGCTATGGGACGCGGCTACGGCCGCTGACGCTGAGCACCC
  CGAAGCCACTGGTGGACTTCTGCAATAAGCCCATCTTGCTGCACCAAGTGGAGGCGCTAG
  CCGCGGCAGGCGTGGACCACGTGATCCTGGCCGTGAGCTACATGTCGCAGGTGCTGGAGA
  AGGAAATGAAGGCACAGGAGCAGAGGCTGGGAATCCGAATCTCCATGTCCCATGAAGAGG
  AGCCTTTGGGGACAGCTGGGCCCCTGGCGCTGGCCCGTGACCTACTCTCTGAGACTGCAG
  ACCCTTTCTTCGTCCTCAACAGTGACGTGATCTGCGATTTCCCCTTCCAAGCCATGGTGC
  AGTTCCACCGGCACCATGGCCAGGAGGGCTCCATCCTGGTGACCAAAGTGGAGGAACCCT
  CCAAGTACGTGTGGTGGTGTGTGAGGCTGACACAGGCCGCATTCACCGGTTTCGTGGAGA
  AGCCACAGGTGTTTTGTTGTCCCAATAGATCAACGCAGCATGTAACATCCTGAGCCCTGC
  AGTGCTGCGGCGCATCCAGCTGCAGCCTACGTCATGGATAGAGTCTCCCATTATGCCCAA
  GGAGGGCAGCTAATATGCATGAGTTAACAGGGCTTCTGGAATGGACATTGACA
• Restriction Sites: Please inquire
• ACCN: NM_021971
• ORF Size: 1083 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_021971.1, NP_068806.1
• RefSeq Size: 1583
• RefSeq ORF: 1083
• Locus ID: 29925
• Domains: hexapep, NTP_transferase
• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways
• Gene Summary: This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (2) lacks a portion of an exon in the 3' coding region compared to variant 1. The encoded isoform (2) lacks an in-frame internal segment and is shorter than isoform 1.