B4GALT7 (NM_007255) Human Untagged Clone

CAT#: SC319505

B4GALT7 (untagged)-Human xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) (B4GALT7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: B4GALT7
• Synonyms: EDSP1; EDSSLA; EDSSPD1; XGALT1; XGPT; XGPT1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_007255.1 GCGGAGCGGGAGGCGGAGGCGCCGCGTAGGCCCGGGAGGCCGGGCCGGCCGGGCTGCGAG
  CGCCTGCCCCATGCGCCGCCGCCTCTCCGCACGATGTTCCCCTCGCGGAGGAAAGCGGCG
  CAGCTGCCCTGGGAGGACGGCAGGTCCGGGTTGCTCTCCGGCGGCCTCCCTCGGAAGTGT
  TCCGTCTTCCACCTGTTCGTGGCCTGCCTCTCGCTGGGCTTCTTCTCCCTACTCTGGCTG
  CAGCTCAGCTGCTCTGGGGACGTGGCCCGGGCAGTCAGGGGACAAGGGCAGGAGACCTCG
  GGCCCTCCCCGCGCCTGCCCCCCAGAGCCGCCCCCTGAGCACTGGGAAGAAGACGCATCC
  TGGGGCCCCCACCGCCTGGCAGTGCTGGTGCCCTTCCGCGAACGCTTCGAGGAGCTCCTG
  GTCTTCGTGCCCCACATGCGCCGCTTCCTGAGCAGGAAGAAGATCCGGCACCACATCTAC
  GTGCTCAACCAGGTGGACCACTTCAGGTTCAACCGGGCAGCGCTCATCAACGTGGGCTTC
  CTGGAGAGCAGCAACAGCACGGACTACATTGCCATGCACGACGTTGACCTGCTCCCTCTC
  AACGAGGAGCTGGACTATGGCTTTCCTGAGGCTGGGCCCTTCCACGTGGCCTCCCCGGAG
  CTCCACCCTCTCTACCACTACAAGACCTATGTCGGCGGCATCCTGCTGCTCTCCAAGCAG
  CACTACCGGCTGTGCAATGGGATGTCCAACCGCTTCTGGGGCTGGGGCCGCGAGGACGAC
  GAGTTCTACCGGCGCATTAAGGGAGCTGGGCTCCAGCTTTTCCGCCCCTCGGGAATCACA
  ACTGGGTACAAGACATTTCGCCACCTGCATGACCCAGCCTGGCGGAAGAGGGACCAGAAG
  CGCATCGCAGCTCAAAAACAGGAGCAGTTCAAGGTGGACAGGGAGGGAGGCCTGAACACT
  GTGAAGTACCATGTGGCTTCCCGCACTGCCCTGTCTGTGGGCGGGGCCCCCTGCACTGTC
  CTCAACATCATGTTGGACTGTGACAAGACCGCCACACCCTGGTGCACATTCAGCTGAGCT
  GGATGGACAGTGAGGAAGCCTGTACCTACAGGCCATATTGCTCAGGCTCAGGACAAGGCC
  TCAGGTCGTGGGCCCAGCTCTGACAGGATGTGGAGTGGCCAGGACCAAGACAGCAAGCTA
  CGCAATTGCAGCCACCCGGCCGCCAAGGCAGGCTTGGGCTGGGCCAGGACACGTGGGGTG
  CCTGGGACGCTGCTTGCCATGCACAGTGATCAGAGAGAGGCTGGGGTGTGTCCTGTCCGG
  GACCCCCCCTGCCTTCCTGCTCACCCTACTCTGACCTCCTTCACGTGCCCAGGCCTGTGG
  GTAGTGGGGAGGGCTGAACAGGACAACCTCTCATCACCCCCACTTTTGTTCCTTCCTGCT
  GGGCTGCCTCGTGCAGAGACACAGTGTAGGGGCCATGCAGCTGGCGTAGGTGGCAGTTGG
  GCCTGGTGAGGGTTAGGACTTCAGAAACCAGAGCACAAGCCCCACAGAGGGGGAACAGCC
  AGCACCGCTCTAGCTGGTTGTTGCCATGCCGGAATGTGGGCCTAGTGTTGCCAGATCTTC
  TGATTTTTCGAAAGAAACTAGAATGCTGGATTCTTAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007255.1 unedited
  GGAAGTACATTGTCATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGCGGAGC
  GGGAGGCGGAGGCGCCGCGTAGGCCCGGGAGGCCGGGCCGGCCGGGCTGCGAGCGCCTGC
  CCCATGCGCCGCCGCCTCTCCGCACGATGTTCCCCTCGCGGAGGAAAGCGGCGCAGCTGC
  CCTGGGAGGACGGCAGGTCCGGGTTGCTCTCCGGCGGCCTCCCTCGGAAGTGTTCCGTCT
  TCCACCTGTTCGTGGCCTGCCTCTCGCTGGGCTTCTTCTCCCTACTCTGGCTGCAGCTCA
  GCTGCTCTGGGGACGTGGCCCGGGCAGTCAGGGGACAAGGGCAGGAGACCTCGGGCCCTC
  CCCGCGCCTGCCCCCCAGAGCCGCCCCCTGAGCACTGGGAAGAAGACGCATCCTGGGGCC
  CCCACCGCCTGGCAGTGCTGGTGCCCTTCCGCGAACGCTTCGAGGAGCTCCTGGTCTTCG
  TGCCCCACATGCGCCGCTTCCTGAGCAGGAAGAAGATCCGGCACCACATCTACGTGCTCA
  ACCAGGTGGACCACTTCAGGTTCAACCGGGCAGCGCTCATCAACGTGGGCTTCCTGGAGA
  GCAGCAACAGCACGGACTACATTGCCATGCACGACGTTGACCTGCTCCCTCTCAACGAGG
  AGCTGGACTATGGCTTTCCTGAGCTGGGCCCTTCCACGTGGCCTCCCCGGAGCTCCACCC
  TCTCTACCACTACAAGACCTATGTCGGCGGCATCCTGCTGCTCTCCAAGCAGCACTACCC
  GGCTGTGCATGGGATGTCCAACCGCTTCTGGGGCTGGGGCCGCGAGGACGACGAGTCTAC
  CGGCGCATAATGAGCTGGGCTCAGCTTTCCGCCCCTCGGGATTCACACTGGTTACAAGAC
  TTCGCCACTGCATGACCAGCTGGCCGAAAGGACAGAAGGCCATCGCAGCCTCAAACTGAC
• Restriction Sites: Please inquire
• ACCN: NM_007255
• ORF Size: 984 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007255.1, NP_009186.1
• RefSeq Size: 1669
• RefSeq ORF: 984
• Locus ID: 11285
• Domains: Galactosyl_T_2
• Protein Families: Transmembrane
• Protein Pathways: Chondroitin sulfate biosynthesis, Heparan sulfate biosynthesis, Metabolic pathways
• Gene Summary: This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome. [provided by RefSeq, Oct 2009]