ALDH4A1 (NM_170726) Human Untagged Clone

CAT#: SC319549

ALDH4A1 (untagged)-Human aldehyde dehydrogenase 4 family, member A1 (ALDH4A1), nuclear gene encoding mitochondrial protein, transcript variant P5CDhS

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALDH4A1
• Synonyms: ALDH4; P5CD; P5CDh
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_170726.1 CCCGCTTCTAACCCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCC
  GCCCCTGGACCGGGGCCGGCCTGCGGTGGAAGCACACCTCCTCCCTGAAGGTGGCCAACG
  AGCCCGTCTTAGCCTTCACGCAGGGCAGCCCTGAGCGAGATGCCCTGCAAAAGGCCTTGA
  AGGACCTGAAGGGCCGGATGGAAGCCATCCCATGCGTGGTGGGGGATGAGGAGGTGTGGA
  CGTCGGACGTGCAGTACCAAGTGTCGCCTTTTAACCATGGACATAAGGTGGCCAAGTTCT
  GTTATGCAGACAAGAGCCTGCTCAACAAAGCCATTGAGGCTGCCCTGGCTGCCCGGAAAG
  AGTGGGACCTGAAGCCTATTGCAGACCGGGCCCAGATCTTCCTGAAGGCGGCAGACATGC
  TGAGTGGGCCGCGCAGGGCTGAGATCCTCGCCAAGACCATGGTGGGACAGGGTAAGACCG
  TGATCCAAGCGGAGATTGACGCTGCAGCGGAACTCATCGACTTCTTCCGGTTCAATGCCA
  AGTATGCGGTGGAGCTGGAGGGGCAGCAGCCCATCAGCGTGCCCCCGAGCACCAACAGCA
  CGGTGTACCGGGGTCTGGAGGGCTTCGTGGCGGCCATCTCGCCCTTTAACTTCACTGCAA
  TCGGCGGCAACCTGGCGGGGGCACCGGCCCTGATGGGCAACGTGGTCCTATGGAAGCCCA
  GTGACACTGCCATGCTGGCCAGCTATGCTGTCTACCGCATCCTTCGGGAGGCTGGCCTGC
  CCCCCAACATCATCCAGTTTGTGCCAGCTGATGGGCCCCTATTTGGGGACACTGTCACCA
  GCTCAGAGCACCTCTGTGGCATCAACTTCACAGGCAGTGTGCCCACCTTCAAACACCTGT
  GGAAGCAGGTGGCCCAGAACCTGGACCGGTTCCACACCTTCCCACGCCTGGCTGGAGAGT
  GCGGCGGAAAGAACTTCCACTTCGTGCACCGCTCGGCCGACGTGGAGAGCGTGGTGAGCG
  GGACCCTCCGCTCAGCCTTCGAGTACGGTGGCCAGAAGTGTTCCGCGTGCTCGCGTCTCT
  ACGTGCCGCACTCGCTGTGGCCGCAGATCAAAGGGCGGCTGCTGGAGGAGCACAGTCGGA
  TCAAAGTGGGCGACCCTGCAGAGGATTTTGGGACCTTCTTCTCTGCAGTGATTGATGCCA
  AGTCCTTTGCCCGTATCAAGAAGTGGCTGGAGCACGCACGCTCCTCACCCAGCCTCACCA
  TCCTGGCCGGGGGCAAGTGTGATGACTCCGTGGGCTACTTTGTGGAGCCCTGCATCGTGG
  AGAGCAAGGACCCTCAGGAGCCCATCATGAAGGAGGAGATCTTCGGGCCTGTACTGTCTG
  TGTACGTCTACCCGGATGACAAGTACAAGGAGACGCTGCAGCTGGTTGACAGCACCACCA
  GCTATGGCCTCACGGGGGCAGTGTTCTCCCAGGATAAGGACGTCGTGCAGGAGGCCACAA
  AGGTGCTGAGGAATGCTGCCGGCAACTTCTACATCAACGACAAGTCCACTGGCTCGATAG
  TGGGCCAGCAGCCCTTTGGGGGGGCCCGAGCCTCTGGAACCAATGACAAGCCAGGGGGCC
  CACACTACATCCTGCGCTGGACGTCGCCGCAGGTCATCAAGGAGACACATAAGCCCCTGG
  GGGACTGGAGCTACGCGTACATGCAGTGAGCCCCTCTCGGGCTCCACCGTCCAGCTGTCT
  GTCCGTCCAGGTGGCCGACCTCACTGCACAGACCCCACTCCAGCCCCTCCACCCCTTCTT
  CATGCACAGCTGCCTTTCTATAATCCGGGCTTGACTCCCTTCTTACCACTGTATTCTGGC
  CTCTCCCATGCCTCAGGCTCTGGTTTGAGATCGTGCTGGGGAGGAACATGGCCACTACCC
  CTTATCCCATCGGCCATGTGGGAGGTATGACCCTGGTGCCTGGCAGGTTCTCCCTCTGCC
  CTCCACTGGGCCCAGTGGCTCAGGGACCTGGGGAAAGGAGATGGAGCAGCTCTTGGGATC
  CTTTGGGGAAAAGGAGGCCATTCTGGGCCCCTTGGCAAACCTCACCACTCACAGAGGCTC
  CTGGCCTTGATCCCTGCCCCTCCAGGTGTCCAGGGTAAAGTGTAACTCAGACTGACCTGT
  GGGGCACAGGGGGCACCAGCTGGCCTTGCCCTCTCTGGTCTGGGCTGTCTACCTTCCTCA
  CTGTATCTTTGCCCAGACCCACCTGGGCCAGTAGGCCCCTGTCCCCAGCCACACACCTTA
  GATGCTGGCATGCCTTACTCCAGGTGCCTGTGTTTGGCCGAGGCCTGTGTGATTCCCGGT
  CTGCACCACATGGCGGGGTTGGGGGGCCGCTGGAGGCCACCTGCCAAGGCGTGGGATGGG
  ATGGTCCTGCCGGTTTAGGCCGTGATTCTGGAAAACCTTGGATGGGCCTTCGTCCTATGT
  CAGCCTTCCCTTTGATCCTCAGGCCCTACCTGTAGAGACCTCCACTCCTAGAGCCAGTCT
  CAGGGTCTGGGATTTCCCTGCAGGAGCTCAGCCACCACTGTGCCATGGTGACACAGGCCA
  AGGCAGACATTGGCCCTCCCTTCTCCCAGCCCCCAGAGGCCTGGCCTTGGGTTCGTCAGC
  ATGGGCCGAGGACGTTGCCTGTAGAATCCTCCTCTGCCTGGGAGTGGCTCTGTGTGGACC
  AGTCCCTCACTGGCCCATTCTTTTTTTGACGCAGCCAATCTGTGACCACGATTCCTCCCA
  CAGATGCCTCCTGCTTGGATTCTGAGTGGTCAGAGATCTGTAAAGCATGACTTTCAAGGA
  TGGTTCTTAGGGGACTGTGAAAGTGTTGGGTCTTCCTCCAGGATGCCTGCATGGGACCCC
  ACCCGGAGCTGGTGTGGCCATTCCCCAAGTGCCACTGGCCCATGGATGGGGGTGGGTGCT
  GGTGCCAGCTGGGCTGGGTGTGGGTTCTGTGTCCTTCCAGGATATGTGTCATTTCCCATG
  AGGGGCCGGGGCAGGTGGCTGGGTGGGGGCACAGGCTGGAGTATTCTTAGTTCTACTGGT
  TCTACACTGTGAGGTGGCAATGGGATTTGCTCAGATGCCACCCAATAAAATGCCTGTTAC
  TTAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_170726.1 unedited
  ACGTTACACATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCCCGCTT
  CTAACCCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTG
  GACCGGGGCCGGCCTGCGGTGGAAGCACACCTCCTCCCTGAAGGTGGCCAACGAGCCCGT
  CTTAGCCTTCACGCAGGGCAGCCCTGAGCGAGATGCCCTGCAAAAGGCCTTGAAGGACCT
  GAAGGGCCGGATGGAAGCCATCCCATGCGTGGTGGGGGATGAGGAGGTGTGGACGTCGGA
  CGTGCAGTACCAAGTGTCGCCTTTTAACCATGGACATAAGGTGGCCAAGTTCTGTTATGC
  AGACAAGAGCCTGCTCAACAAAGCCATTGAGGCTGCCCTGGCTGCCCGGAAAGAGTGGGA
  CCTGAAGCCTATTGCAGACCGGGCCCAGATCTTCCTGAAGGCGGCAGACATGCTGAGTGG
  GCCGCGCAGGGCTGAGATCCTCGCCAAGACCATGGTGGGACAGGGTAAGACCGTGATCCA
  AGCGGAGATTGACGCTGCAGCGGAACTCATCGACTTCTTCCGGTTCAATGCCAAGTATGC
  GGTGGAGCTGGAGGGGCAGCAGCCCATCAGCGTGCCCCCGAGCACCAACAGCACGGTGTA
  CCGGGGTCTGGAGGGCTTCGTGGCGGCCATCTCGCCCTTTAACTTCACTGCAATCGGCGG
  CAACCTGGCGGGGGCACCGGCCCTGATGGGCAACGTGGTCCTATGGGAAGCCCAGTGACC
  ACTGCCATGCTGGCCAGCTATGCTGTCTACCGCATCCTTCGGGAGGCTGGCCTGCCCCCA
  ACATCATCCAGTTTGTGCAGCTGATGGCCCCTATTGGGGACACTGTCACAGCTCAAAACA
  CCTTCTGTGGCATCACTTCACAGGGC
• Restriction Sites: Please inquire
• ACCN: NM_170726
• ORF Size: 1692 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_170726.1, NP_733844.1
• RefSeq Size: 2147
• RefSeq ORF: 1692
• Locus ID: 8659
• Protein Families: Druggable Genome
• Protein Pathways: Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways
• Gene Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2009]
  Transcript Variant: This variant (P5CDhS) differs in the 3' UTR compared to variant P5CDhL. Both variants P5CDhL and P5CDhS encode the same protein (isoform a).