TCP1 epsilon (CCT5) (NM_012073) Human Untagged Clone

CAT#: SC319578

CCT5 (untagged)-Human chaperonin containing TCP1, subunit 5 (epsilon) (CCT5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCT5
• Synonyms: CCT-epsilon; CCTE; HEL-S-69; PNAS-102; TCP-1-epsilon
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012073.3 GCCCTCCCGAGAAAGGGAAGTGCATTCTCGCTTCCGTAGCGGTCTCCGCCGGTTGGGGGA
  AAGTAATTCCGGCTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGATGAATATGG
  GCGCCCTTTCCTCATCATCAAGGATCAGGACCGCAAGTCCCGTCTTATGGGACTTGAGGC
  CCTCAAGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGG
  ACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGGGATGTGACTGTAACTAATGA
  TGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAGATTGCCAAGCTGATGGTGGA
  ACTGTCCAAGTCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGC
  TGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAAT
  AGCCGATGGCTATGAGCAGGCTGCTCGCGTTGCTATTGAACACCTGGACAAGATCAGCGA
  TAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCT
  GGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGT
  CCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGG
  CAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGA
  TTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATG
  TCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGA
  TTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAA
  AGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTT
  ACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGAT
  TGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCT
  GGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGT
  CATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGAT
  GATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCAT
  CCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGT
  TAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGA
  CGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGAC
  TATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTG
  TTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAA
  AAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACAT
  TCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCAC
  TTCTGTGATTAAGTAAATGGATGTCTCGTGATGCGTCTACAGTTATTTATTGTTACATCC
  TTTTCCAGACACTGTAGATGCTATAATAAAAATAGCTGTTTGGTAACCATAGTTTCACTT
  GTTCAAAGCTGTGTAATCGTGGGGGTACTATCTCAACTGCTTTTGTATTCATTGTATTAA
  AAGAATCTGTTTAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012073.3 unedited
  GTCGATTGTAGCTCAAGATGTACACGACCTCCTACTAGGGCGGCCGGGAATTCTCGGCAC
  GAGGGCCCTCCCGAGAAAGGGAAGCTGCATTTCTCGCTTTCCGTAGCGGTCTCCGCCGGT
  TGGGGGAAAGTAATTTCCGGCTTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGA
  TGAATATGGGCGCCCTTTCCTCATCATCAAGGAACAGGACCGCAAGTCCCGTCTTATGGG
  ACTTGAGGCCCTCAAGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAAC
  ATCACTTGGACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGGGATGTGACTGT
  AACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAGATTGCCAAGCT
  GATGGTGGAACTGTCCAAGTCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGTGGT
  TGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCC
  AATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGCGTTGCTATTGAACACCTGGACAA
  GATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAA
  AACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGT
  GAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAA
  AGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGCGTGATTGTG
  GACAAGATTTCAGTCACCCCACAGATGCCAAAAAAAAGTGGAGATGCGAAGATTGCAATT
  CTCACATGTCCATTTTGAACCCACCAACCAAAACAAAGCATAGCTGGATGTGACCTCTGG
  TCGAAAAATTTATAAGGCCCTTCGAAAAATACGGA
• Restriction Sites: Please inquire
• ACCN: NM_012073
• ORF Size: 1626 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012073.3, NP_036205.1
• RefSeq Size: 3403
• RefSeq ORF: 1626
• Locus ID: 22948
• Domains: cpn60_TCP1
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).