MARCO (NM_006770) Human Untagged Clone

CAT#: SC319619

MARCO (untagged)-Human macrophage receptor with collagenous structure (MARCO)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MARCO
• Synonyms: SCARA2; SR-A6
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006770.3 GGGGGCCAAAGGGAAGTGCTGCGAGGTTTACAACCAGCTGCAGTGGTTCGATGGGAAGGA
  TCTTTCTCCAAGTGGTTCCTCTTGAGGGGAGCATTTCTGCTGGCTCCAGGACTTTGGCCA
  TCTATAAAGCTTGGCAATGAGAAATAAGAAAATTCTCAAGGAGGACGAGCTCTTGAGTGA
  GACCCAACAAGCTGCTTTTCACCAAATTGCAATGGAGCCTTTCGAAATCAATGTTCCAAA
  GCCCAAGAGGAGAAATGGGGTGAACTTCTCCCTAGCTGTGGTGGTCATCTACCTGATCCT
  GCTCACCGCTGGCGCTGGGCTGCTGGTGGTCCAAGTTCTGAATCTGCAGGCGCGGCTCCG
  GGTCCTGGAGATGTATTTCCTCAATGACACTCTGGCGGCTGAGGACAGCCCGTCCTTCTC
  CTTGCTGCAGTCAGCACACCCTGGAGAACACCTGGCTCAGGGTGCATCGAGGCTGCAAGT
  CCTGCAGGCCCAACTCACCTGGGTCCGCGTCAGCCATGAGCACTTGCTGCAGCGGGTAGA
  CAACTTCACTCAGAACCCAGGGATGTTCAGAATCAAAGGTGAACAAGGCGCCCCAGGTCT
  TCAAGGCCACAAGGGGGCCATGGGCATGCCTGGTGCCCCTGGCCCGCCGGGACCACCTGC
  TGAGAAGGGAGCCAAGGGGGCTATGGGACGAGATGGAGCAACAGGCCCCTCGGGACCCCA
  AGGCCCACCGGGAGTCAAGGGAGAGGCGGGCCTCCAAGGACCCCAGGGTGCTCCAGGGAA
  GCAAGGAGCCACTGGCACCCCAGGACCCCAAGGAGAGAAGGGCAGCAAAGGCGATGGGGG
  TCTCATTGGCCCAAAAGGGGAAACTGGAACTAAGGGAGAGAAAGGAGACCTGGGTCTCCC
  AGGAAGCAAAGGGGACAGGGGCATGAAAGGAGATGCAGGGGTCATGGGGCCTCCTGGAGC
  CCAGGGGAGTAAAGGTGACTTCGGGAGGCCAGGCCCACCAGGTTTGGCTGGTTTTCCTGG
  AGCTAAAGGAGATCAAGGACAACCTGGACTGCAGGGTGTTCCGGGCCCTCCTGGTGCAGT
  GGGACACCCAGGTGCCAAGGGTGAGCCTGGCAGTGCTGGCTCCCCTGGGCGAGCAGGACT
  TCCAGGGAGCCCCGGGAGTCCAGGAGCCACAGGCCTGAAAGGAAGCAAAGGGGACACAGG
  ACTTCAAGGACAGCAAGGAAGAAAAGGAGAATCAGGAGTTCCAGGCCCTGCAGGTGTGAA
  GGGAGAACAGGGGAGCCCAGGGCTGGCAGGTCCCAAGGGAGCCCCTGGACAAGCTGGCCA
  GAAGGGAGACCAGGGAGTGAAAGGATCTTCTGGGGAGCAAGGAGTAAAGGGAGAAAAAGG
  TGAAAGAGGTGAAAACTCAGTGTCCGTCAGGATTGTCGGCAGTAGTAACCGAGGCCGGGC
  TGAAGTTTACTACAGTGGTACCTGGGGGACAATTTGCGATGACGAGTGGCAAAATTCTGA
  TGCCATTGTCTTCTGCCGCATGCTGGGTTACTCCAAAGGAAGGGCCCTGTACAAAGTGGG
  AGCTGGCACTGGGCAGATCTGGCTGGATAATGTTCAGTGTCGGGGCACGGAGAGTACCCT
  GTGGAGCTGCACCAAGAATAGCTGGGGCCATCATGACTGCAGCCACGAGGAGGACGCAGG
  CGTGGAGTGCAGCGTCTGACCCGGAAACCCTTTCACTTCTCTGCTCCCGAGGTGTCCTCG
  GGCTCATATGTGGGAAGGCAGAGGATCTCTGAGGAGTTCCCTGGGGACAACTGAGCAGCC
  TCTGGAGAGGGGCCATTAATAAAGCTCAACATCAAAAAAAAAAAAGAAAAAAAAAAAAAA
  AAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006770.3 unedited
  TCGATTGTATACGACTCCTATAGGGCGGCCGGGTAATTCGGCCTTACGGCCGGGGGCCAA
  AGGGAAGTGCTGCGAGGTTTACAACCAGCTGCAGTGGTTCGATGGGAAGGATCTTTCTCC
  AAGTGGTTCCTCTTGAGGGGAGCATTTCTGCTGGCTCCAGGACTTTGGCCATCTATAAAG
  CTTGGCAATGAGAAATAAGAAAATTCTCAAGGAGGACGAGCTCTTGAGTGAGACCCAACA
  AGCTGCTTTTCACCAAATTGCAATGGAGCCTTTCGAAATCAATGTTCCAAAGCCCAAGAG
  GAGAAATGGGGTGAACTTCTCCCTAGCTGTGGTGGTCATCTACCTGATCCTGCTCACCGC
  TGGCGCTGGGCTGCTGGTGGTCCAAGTTCTGAATCTGCAGGCGCGGCTCCGGGTCCTGGA
  GATGTATTTCCTCAATGACACTCTGGCGGCTGAGGACAGCCCGTCCTTCTCCTTGCTGCA
  GTCAGCACACCCTGGAGAACACCTGGCTCAGGGTGCATCGAGGCTGCAAGTCCTGCAGGC
  CCAACTCACCTGGGTCCGCGTCAGCCATGAGCACTTGCTGCAGCGGGTAGACAACTTCAC
  TCAGAACCCAGGGATGTTCAGAATCAAAGGTGAACAAGGCGCCCCAGTCTTCAAGGCCCA
  CAAGGGGGCCATGGGCATGCCTGGTGCCCCTGGCCCGCCGGGACCACCTGCTGAGAGGAG
  CCAAGGGGGCTATGGGACGAGATGAGCACAGCCCCTCGGGACCCCAAGCCCACCGGGAGT
  CAGGGAGAGGCGGCCTCCAGACCCAGTGCTCAGGAGCAGACCACTGCACCCAGGACCAGA
  AGAAGCAGCAGCATGGGGTTCTCATTGCCCAAAGGTAACTTGACTAAGGGAGAAGAAAAG
  AAACCTGG
• Restriction Sites: Please inquire
• ACCN: NM_006770
• ORF Size: 1563 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006770.3, NP_006761.1
• RefSeq Size: 1853
• RefSeq ORF: 1563
• Locus ID: 8685
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]