PARP3 (NM_005485) Human Untagged Clone

CAT#: SC319646

PARP3 (untagged)-Human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2


  "NM_005485" in other vectors (7)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PARP3
Synonyms ADPRT3; ADPRTL2; ADPRTL3; ARTD3; IRT1; PADPRT-3
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_005485.3 CACAGGACAGCCATGGCTCCAAAGCCGAAGCCCTGGGTACAGACTGAGGGCCCTGAGAAG
AAGAAGGGCCGGCAGGCAGGAAGGGAGGAGGACCCCTTCCGCTCCACCGCTGAGGCCCTC
AAGGCCATACCCGCAGAGAAGCGCATAATCCGCGTGGATCCAACATGTCCACTCAGCAGC
AACCCCGGGACCCAGGTGTATGAGGACTACAACTGCACCCTGAACCAGACCAACATCGAG
AACAACAACAACAAGTTCTACATCATCCAGCTGCTCCAAGACAGCAACCGCTTCTTCACC
TGCTGGAACCGCTGGGGCCGTGTGGGAGAGGTCGGCCAGTCAAAGATCAACCACTTCACA
AGGCTAGAAGATGCAAAGAAGGACTTTGAGAAGAAATTTCGGGAAAAGACCAAGAACAAC
TGGGCAGAGCGGGACCACTTTGTGTCTCACCCGGGCAAGTACACACTTATCGAAGTACAG
GCAGAGGATGAGGCCCAGGAAGCTGTGGTGAAGGTGGACAGAGGCCCAGTGAGGACTGTG
ACTAAGCGGGTGCAGCCCTGCTCCCTGGACCCAGCCACGCAGAAGCTCATCACTAACATC
TTCAGCAAGGAGATGTTCAAGAACACCATGGCCCTCATGGACCTGGATGTGAAGAAGATG
CCCCTGGGAAAGCTGAGCAAGCAACAGATTGCACGGGGTTTCGAGGCCTTGGAGGCGCTG
GAGGAGGCCCTGAAAGGCCCCACGGATGGTGGCCAAAGCCTGGAGGAGCTGTCCTCACAC
TTTTACACCGTCATCCCGCACAACTTCGGCCACAGCCAGCCCCCGCCCATCAATTCCCCT
GAGCTTCTGCAGGCCAAGAAGGACATGCTGCTGGTGCTGGCGGACATCGAGCTGGCCCAG
GCCCTGCAGGCAGTCTCTGAGCAGGAGAAGACGGTGGAGGAGGTGCCACACCCCCTGGAC
CGAGACTACCAGCTTCTCAAGTGCCAGCTGCAGCTGCTAGACTCTGGAGCACCTGAGTAC
AAGGTGATACAGACCTACTTAGAACAGACTGGCAGCAACCACAGGTGCCCTACACTTCAA
CACATCTGGAAAGTAAACCAAGAAGGGGAGGAAGACAGATTCCAGGCCCACTCCAAACTG
GGTAATCGGAAGCTGCTGTGGCATGGCACCAACATGGCCGTGGTGGCCGCCATCCTCACT
AGTGGGCTCCGCATCATGCCACATTCTGGTGGGCGTGTTGGCAAGGGCATCTACTTTGCC
TCAGAGAACAGCAAGTCAGCTGGATATGTTATTGGCATGAAGTGTGGGGCCCACCATGTC
GGCTACATGTTCCTGGGTGAGGTGGCCCTGGGCAGAGAGCACCATATCAACACGGACAAC
CCCAGCTTGAAGAGCCCACCTCCTGGCTTCGACAGTGTCATTGCCCGAGGCCACACCGAG
CCTGATCCGACCCAGGACACTGAGTTGGAGCTGGATGGCCAGCAAGTGGTGGTGCCCCAG
GGCCAGCCTGTGCCCTGCCCAGAGTTCAGCAGCTCCACATTCTCCCAGAGCGAGTACCTC
ATCTACCAGGAGAGCCAGTGTCGCCTGCGCTACCTGCTGGAGGTCCACCTCTGAGTGCCC
GCCCTGTCCCCCGGGGTCCTGCAAGGCTGGACTGTGATCTTCAATCATCCTGCCCATCTC
TGGTACCCCTATATCACTCCTTTTTTTCAAGAATACAATACGTTGTTGTTAACTATAGTC
ACCATGCTGTACAAGATCCCTGAACTTATGCCTCCTAACTGAAATTTTGTATTCTTTGAC
ACATCTGCCCAGTCCCTCTCCTCCCAGCCCATGGTAACCAGCATTTGACTCTTTACTTGT
ATAAGGGCAGCTTTTATAGGTTCCACATGTAAGTGAGATCATGCAGTGTTTGTCTTTCTG
TGCCTGGCTTATTTCACTCAGCATAATGTGCACCGGGTTCACCCATGTTTTCATAAATGA
CAAGATTTCCTCCTTAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_005485.3 unedited
GCGTGTCTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCACAGGACA
GCCATGGCTCCAAAGCCGAAGCCCTGGGTACAGACTGAGGGCCCTGAGAAGAAGAAGGGC
CGGCAGGCAGGAAGGGAGGAGGACCCCTTCCGCTCCACCGCTGAGGCCCTCAAGGCCATA
CCCGCAGAGAAGCGCATAATCCGCGTGGATCCAACATGTCCACTCAGCAGCAACCCCGGG
ACCCAGGTGTATGAGGACTACAACTGCACCCTGAACCAGACCAACATCGAGAACAACAAC
AACAAGTTCTACATCATCCAGCTGCTCCAAGACAGCAACCGCTTCTTCACCTGCTGGAAC
CGCTGGGGCCGTGTGGGAGAGGTCGGCCAGTCAAAGATCAACCACTTCACAAGGCTAGAA
GATGCAAAGAAGGACTTTGAGAAGAAATTTCGGGAAAAGACCAAGAACAACTGGGCAGAG
CGGGACCACTTTGTGTCTCACCCGGGCAAGTACACACTTATCGAAGTACAGGCAGAGGAT
GAGGCCCAGGAAGCTGTGGTGAAGGTGGACAGAGGCCCAGTGAGGACTGTGACTAAGCGG
GTGCAGCCCTGCTCCCTGGACCCAGCCACGCAGAAGCTCATCACTAACATCTTCAGCAAG
GAGATGTTCAAGACACCATGGCCCTCATGGACCTGGATGTGAAGAAGATGCCCCTGGGAA
AGCTGAGCAAGCAACAGATTGCACGGGTTTCGAGGCCTTGGAGGCGCTGGAGGAGGCCCT
GAAAGCCCCACGGATGGTGGCCAAAGCCTGAGGAGCTGTCCTCACCACTTTTAACACCGT
CATCCCGCACAACTTCGGCCACAGGCCAGGCCCCCGCCCATCAATTCCCCTGGAGCTTCT
GCAGCAGAGACATGCTGCTGTGCTGCGACATCGAGCTGCCCAGCCTGCAGCAGTCTTCTG
GACAGA
Restriction Sites Please inquire     
ACCN NM_005485
ORF Size 1599 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_005485.3, NP_005476.2
RefSeq Size 2373
RefSeq ORF 1599
Locus ID 10039
Domains PARP, PARP_reg
Protein Families Druggable Genome
Protein Pathways Base excision repair
Gene Summary The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (2) differs in the 5' UTR and uses a downstream translational start codon, compared to variant 1. The resulting isoform (b) is shorter at the N-terminus, compared to isoform a.

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