TUSC3 (NM_178234) Human Untagged Clone

CAT#: SC319771

TUSC3 (untagged)-Human tumor suppressor candidate 3 (TUSC3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TUSC3
• Synonyms: D8S1992; M33; MagT2; MRT7; MRT22; N33; OST3A; SLC58A2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_178234.1 GGGGGCCTTTCCAGGTCTTCTCCCGGTGAACCGGATGCTCTGTCAGTCTCCTCCTCTGCG
  TCCTCGGCCGCGGCCCGGGTCCCTCGCAAAGCCGCTGCCATCCCGGAGGGCCCAGCCAGC
  GGGCTCCCGGAGGCTGGCCGGGCAGGCGTGGTGCGCGGTAGGAGCTGGGCGCGCACGGCT
  ACCGCGCGTGGAGGAGACACTGCCCTGCCGCGATGGGGGCCCGGGGCGCTCCTTCACGCC
  GTAGGCAAGCGGGGCGGCGGCTGCGGTACCTGCCCACCGGGAGCTTTCCCTTCCTTCTCC
  TGCTGCTGCTGCTCTGCATCCAGCTCGGGGGAGGACAGAAGAAAAAGGAGAATCTTTTAG
  CTGAAAAAGTAGAGCAGCTGATGGAATGGAGTTCCAGACGCTCAATCTTCCGAATGAATG
  GTGATAAATTCCGAAAATTTATAAAGGCACCACCTCGAAACTATTCCATGATTGTTATGT
  TCACTGCTCTTCAGCCTCAGCGGCAGTGTTCTGTGTGCAGGCAAGCTAATGAAGAATATC
  AAATACTGGCGAACTCCTGGCGCTATTCATCTGCTTTTTGTAACAAGCTCTTCTTCAGTA
  TGGTGGACTATGATGAGGGGACAGACGTTTTTCAGCAGCTCAACATGAACTCTGCTCCTA
  CATTCATGCATTTTCCTCCAAAAGGCAGACCTAAGAGAGCTGATACTTTTGACCTCCAAA
  GAATTGGATTTGCAGCTGAGCAACTAGCAAAGTGGATTGCTGACAGAACGGATGTTCATA
  TTCGGGTTTTCAGACCACCCAACTACTCTGGTACCATTGCTTTGGCCCTGTTAGTGTCGC
  TTGTTGGAGGTTTGCTTTATTTGAGAAGGAACAACTTGGAGTTCATCTATAACAAGACTG
  GTTGGGCCATGGTGTCTCTGTGTATAGTCTTTGCTATGACTTCTGGCCAGATGTGGAACC
  ATATCCGTGGACCTCCATATGCTCATAAGAACCCACACAATGGACAAGTGAGCTACATTC
  ATGGGAGCAGCCAGGCTCAGTTTGTGGCAGAATCACACATTATTCTGGTACTGAATGCCG
  CTATCACCATGGGGATGGTTCTTCTAAATGAAGCAGCAACTTCGAAAGGCGATGTTGGAA
  AAAGACGGATAATTTGCCTAGTGGGATTGGGCCTGGTGGTCTTCTTCTTCAGTTTTCTAC
  TTTCAATATTTCGTTCCAAGTACCACGGCTATCCTTATAGCTTTTTAATTAAATGAAGCC
  AAGTGGGATTTGCATAAAGTGAATGTTTACCATGAAGATAAACTGTTCCTGACTTTATAC
  TATTTTGAATTCATTCATTTCATTGTGATCAGCTAGCTTATTCTTGTGTACTTTTTTTAA
  ACTGTGGGTTTTCCTAGTAAATTTAATTTACAGAAATCAATGGTAGCATTTAGTAATCTA
  CAAAGGAAATATCAAAGTGTTTTTCAAGCCTGTTATATTCAGTGTGTGCCACAGGATTGA
  AATAAATGACAATGTAATTATGAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_178234.1 unedited
  GCGTAGCTTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCCATTACGGCCGGGGG
  CCTTTCCAGGTCTTCTCCCGGTGAACCGGATGCTCTGTCAGTCTCCTCCTCTGCGTCCTC
  GGCCGCGGCCCGGGTCCCTCGCAAAGCCGCTGCCATCCCGGAGGGCCCAGCCAGCGGGCT
  CCCGGAGGCTGGCCGGGCAGGCGTGGTGCGCGGTAGGAGCTGGGCGCGCACGGCTACCGC
  GCGTGGAGGAGACACTGCCCTGCCGCGATGGGGGCCCGGGGCGCTCCTTCACGCCGTAGG
  CAAGCGGGGCGGCGGCTGCGGTACCTGCCCACCGGGAGCTTTCCCTTCCTTCTCCTGCTG
  CTGCTGCTCTGCATCCAGCTCGGGGGAGGACAGAAGAAAAAGGAGAATCTTTTAGCTGAA
  AAAGTAGAGCAGCTGATGGAATGGAGTTCCAGACGCTCAATCTTCCGAATGAATGGTGAT
  AAATTCCGAAAATTTATAAAGGCACCACCTCGAAACTATTCCATGATTGTTATGTTCACT
  GCTCTTCAGCCTCAGCGGCAGTGTTCTGTGTGCAGGCAAGCTAATGAAGAATATCAAATA
  CTGGCGAACTCCTGGCGCTATTCATCTGCTTTTTGTAACAAGCTCTTCTTCAGTATGGTG
  GACTATGATGAGGGGACAGACGTTTTTCAGCAGCTCAACATGAACTCTGCTCCTACATTC
  ATGCATTTTCCTCCAAAGGCAGACCTAAGAGAGCTGATACTTTTGACCTCCAAGATTGGA
  TTTGCAGCTGAGCAACTAGCAAGTGATTGCTGACAGACGGATGTTCATATTCGGTTTCAG
  ACCACCCACTACTCTGTACATTGCTTTGCCCTGTTAGTGTCCGCTTGTTGAGTTTGCTTT
  ATTTGAGAAGAACCACCTG
• Restriction Sites: Please inquire
• ACCN: NM_178234
• ORF Size: 1044 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_178234.1, NP_839952.1
• RefSeq Size: 1548
• RefSeq ORF: 1044
• Locus ID: 7991
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: This gene encodes a protein that has been associated with several biological functions including cellular magnesium uptake, protein glycosylation and embryonic development. This protein localizes to the endoplasmic reticulum and acts as a component of the oligosaccharyl transferase complex which is responsible for N-linked protein glycosylation. This gene is a candidate tumor suppressor gene. Homozygous mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation-7 and in the proliferation and invasiveness of several cancers including metastatic pancreatic cancer, ovarian cancer and glioblastoma multiform. [provided by RefSeq, Oct 2017]
  Transcript Variant: This variant (2) lacks an exon in the 3' region compared to variant 1. The resulting isoform (b) contains a one aa shorter and distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.