MMAB (NM_052845) Human Untagged Clone

CAT#: SC319907

MMAB (untagged)-Human methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MMAB
• Synonyms: ATR; cblB; CFAP23; cob
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_052845.3 GTCAAGCAGCCTGGCTCATGGCTGTGTGCGGCCTGGGGAGCCGTCTTGGCCTGGGGAGCC
  GTCTTGGCCTGCGCGGGTGCTTCGGCGCCGCCAGGCTCCTGTATCCCCGTTTCCAGAGCC
  GCGGCCCTCAGGGCGTGGAAGACGGGGACAGGCCACAGCCTTCCTCGAAGACACCCAGGA
  TCCCCAAGATTTACACCAAAACGGGAGACAAAGGGTTTTCTAGTACCTTCACAGGAGAAA
  GGAGACCCAAAGATGACCAAGTGTTTGAAGCCGTGGGAACTACAGATGAATTAAGTTCAG
  CTATTGGGTTTGCTCTGGAATTAGTCACAGAAAAGGGCCATACATTTGCCGAAGAGCTTC
  AGAAAATCCAGTGCACATTGCAGGACGTCGGCTCGGCCCTGGCGACACCATGCTCCTCGG
  CCCGGGAGGCTCACTTAAAGTATACCACGTTCAAGGCGGGGCCCATCCTGGAGCTGGAGC
  AGTGGATCGACAAGTACACCAGCCAGCTCCCACCACTCACGGCCTTCATCCTGCCTTCGG
  GAGGCAAGATCAGCTCGGCGCTGCATTTCTGCCGGGCCGTGTGCCGCCGGGCCGAGAGAC
  GTGTGGTGCCTCTTGTCCAGATGGGAGAGACCGATGCGAACGTGGCCAAGTTCTTAAACA
  GACTCAGTGACTATCTCTTCACGCTAGCCAGATATGCAGCCATGAAGGAGGGGAATCAAG
  AGAAAATATACATGAAAAATGACCCATCGGCCGAGTCTGAGGGACTCTGAAATCACAGAA
  AGTGGGAGCTTGGAGGATCCCTCCATGGCGATGGCCGTGGAGAGAGGAGCTTGCCCTTCT
  GGGGTCCTGGTTCCTGAAGAGCTCACCCAGAGAGGCTCAAAGCAGCCTTTTGTCCCAGCT
  CAGCTTTGATCTACACCTCTTGCCACCTTCCTCAAGGGACTGTGACCCTTTGGGGATTCT
  GTCCCTGACCCTGCTTCCCCAAGCTCTCCTGGGTCTTGGAGGGATGTGGGAATGAATTGG
  CATTGCAGGAAAGACAGGTAAAGTGATTGCTGCAATGAGAAGGAGCTGTGCGGAAAAGGA
  ATAAAAGTTGGAAAGGCTGGAGCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT
  GTGTGTGTGAGAGAGAGCCCTCCCACTGCCAGCTCAGGTTGTTCACAGATTTGGAATGGG
  ACCAGAGGCCCTTGAAAATGTAATTGTGATTTACCTGTGCCAAAGGTGCTTTAAATGTCA
  CATTTGTAAAGGGGAAGGCGGACAAGATTTGGAAGTTTAGTCACCTCTGAGCCACCCATC
  ACCGCCAAAGTGTGGGGGAAGGATAGCTGCAGATTGACAGGCGAGGCTCAGAAACTCCTG
  GCTTAGATTGAAGTGTGTGTGATGGGGGTGCAGCTTAGAGGACCCCCTCTGAAAGGGATG
  GAGATGCTGATGAGAACAACACTACCACTTGAAGGTGAACATTCCCTGTCTGGTTGGACT
  GAGTCAAGGGTCTGCGGTGCAGCATCTTCAGCTTGAGAAAATGAGGTTGTCAGTTTCCAG
  CAAGGCTGACATCCACCAGACTGATTTCTCCGATGTTGCACTTGGCTGGCTTATGCCTCT
  GAGATCGGTGCCACGGCTGTATTTATTTCAGTTGTCACTGCTGCTCCCTCCTGCTATGAA
  ACGACACTGCCAGTGCCAGCAGTGTCCTTGGGAAAGGCAATATTTATGAAGGGCAGAAGA
  GGCAGCCCCAAGAACCTAAAGACTGCAGGCTGCTAATTGCAGGAAATGACTTTGGAAGGG
  CAGGCTCTTGTCCAGTTTCAGGGCTGAAATGCCTGGCGAACTCCATTCAGCCATCACATA
  TTGACTGAGTGGCTGCTTAGCATGGGCCACCGCGCTAGGCTCGGGACAGCTGGTCTTTCC
  GGCCATCTTTCTTGCTGGCAAGTCAGCAAACATTACCTTCTTAGTCACGTGCATATTTTT
  GCCTTCATTCTTACCACCTGGCCTGCAAAGTTTGCAGGAGGGCCAGGTATATTCACTTGT
  GTCTTCTGGGTCCTTTCATTGCTGACAGGCTGTGATGGCCCTCTTGAGCCTTGGGCAGGG
  TGGGTGAGGTGCAGATGACCAGGAGTGTGTGAATGCCTTCCAGGAGGTGGCTTTGTTCCG
  TGCCTCCCTGCCCCCATCGTCACTACCAGGTCTGGTACGGAGTCGGTGCTCAGTGTTTGC
  AAAACAGAGCTGAAAACGGACTTTGGGAGGCCGAGGCAGGCAGATCACCTGAGGTCAGGA
  GTTTGAGACCAGCCTGGTCAACATGGTAAAACCCCATTTCTGCTAAAAAAAAAAAAAAAA
  AAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_052845.3 unedited
  TGCATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGTCAAGCAGCCTG
  GCTCATGGCTGTGTGCGGCCTGGGGAGCCGTCTTGGCCTGGGGAGCCGTCTTGGCCTGCG
  CGGGTGCTTCGGCGCCGCCAGGCTCCTGTATCCCCGTTTCCAGAGCCGCGGCCCTCAGGG
  CGTGGAAGACGGGGACAGGCCACAGCCTTCCTCGAAGACACCCAGGATCCCCAAGATTTA
  CACCAAAACGGGAGACAAAGGGTTTTCTAGTACCTTCACAGGAGAAAGGAGACCCAAAGA
  TGACCAAGTGTTTGAAGCCGTGGGAACTACAGATGAATTAAGTTCAGCTATTGGGTTTGC
  TCTGGAATTAGTCACAGAAAAGGGCCATACATTTGCCGAAGAGCTTCAGAAAATCCAGTG
  CACATTGCAGGACGTCGGCTCGGCCCTGGCGACACCATGCTCCTCGGCCCGGGAGGCTCA
  CTTAAAGTATACCACGTTCAAGGCGGGGCCCATCCTGGAGCTGGAGCAGTGGATCGACAA
  GTACACCAGCCAGCTCCCACCACTCACGGCCTTCATCCTGCCTTCGGGAGGCAAGATCAG
  CTCGGCGCTGCATTTCTGCCGGGCCGTGTGCCGCCGGGCCGAGAGACGTGTGGTGCCTCT
  TGTCCAGATGGGAGAGACCGATGCGAACGTGGCCAAGTTCTTAAACAGACTCAGTGACTA
  TCTCTTCACGCTAGCCAGATATGCAGCCATGAAGAGGGAATCAAGAGAAAATATACATGA
  AAAATGACCCATCGCCCGAGTCTGAGGGACTCTGAAATCACAGAAAGTGGGAGCTGAGAT
  CCCTCATGGCGATGGCCGTGGAGAGAGGAGCTGCCTCTGGGTCCTGTCTGATGCCTCACC
  CAAGAGCTCAAGCAGCTTTGTCCAGCTCAGCTTGATCTAACCCTCTGGCACTCTCAGAAC
  TTGGAACCCTTTGGATTCTGTACTGACCTGCTCCAGCCTCTCCTGAC
• Restriction Sites: Please inquire
• ACCN: NM_052845
• ORF Size: 753 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_052845.3, NP_443077.1
• RefSeq Size: 4154
• RefSeq ORF: 753
• Locus ID: 326625
• Domains: DUF80
• Protein Pathways: Metabolic pathways, Porphyrin and chlorophyll metabolism
• Gene Summary: This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found. [provided by RefSeq, Apr 2011]
  Transcript Variant: This variant (1) encodes a functional protein.