MMAB (NM_052845) Human Untagged Clone

CAT#: SC319907

MMAB (untagged)-Human methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), nuclear gene encoding mitochondrial protein, transcript variant 1


  "NM_052845" in other vectors (4)

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol MMAB
Synonyms ATR; cblB; CFAP23; cob
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_052845.3 GTCAAGCAGCCTGGCTCATGGCTGTGTGCGGCCTGGGGAGCCGTCTTGGCCTGGGGAGCC
GTCTTGGCCTGCGCGGGTGCTTCGGCGCCGCCAGGCTCCTGTATCCCCGTTTCCAGAGCC
GCGGCCCTCAGGGCGTGGAAGACGGGGACAGGCCACAGCCTTCCTCGAAGACACCCAGGA
TCCCCAAGATTTACACCAAAACGGGAGACAAAGGGTTTTCTAGTACCTTCACAGGAGAAA
GGAGACCCAAAGATGACCAAGTGTTTGAAGCCGTGGGAACTACAGATGAATTAAGTTCAG
CTATTGGGTTTGCTCTGGAATTAGTCACAGAAAAGGGCCATACATTTGCCGAAGAGCTTC
AGAAAATCCAGTGCACATTGCAGGACGTCGGCTCGGCCCTGGCGACACCATGCTCCTCGG
CCCGGGAGGCTCACTTAAAGTATACCACGTTCAAGGCGGGGCCCATCCTGGAGCTGGAGC
AGTGGATCGACAAGTACACCAGCCAGCTCCCACCACTCACGGCCTTCATCCTGCCTTCGG
GAGGCAAGATCAGCTCGGCGCTGCATTTCTGCCGGGCCGTGTGCCGCCGGGCCGAGAGAC
GTGTGGTGCCTCTTGTCCAGATGGGAGAGACCGATGCGAACGTGGCCAAGTTCTTAAACA
GACTCAGTGACTATCTCTTCACGCTAGCCAGATATGCAGCCATGAAGGAGGGGAATCAAG
AGAAAATATACATGAAAAATGACCCATCGGCCGAGTCTGAGGGACTCTGAAATCACAGAA
AGTGGGAGCTTGGAGGATCCCTCCATGGCGATGGCCGTGGAGAGAGGAGCTTGCCCTTCT
GGGGTCCTGGTTCCTGAAGAGCTCACCCAGAGAGGCTCAAAGCAGCCTTTTGTCCCAGCT
CAGCTTTGATCTACACCTCTTGCCACCTTCCTCAAGGGACTGTGACCCTTTGGGGATTCT
GTCCCTGACCCTGCTTCCCCAAGCTCTCCTGGGTCTTGGAGGGATGTGGGAATGAATTGG
CATTGCAGGAAAGACAGGTAAAGTGATTGCTGCAATGAGAAGGAGCTGTGCGGAAAAGGA
ATAAAAGTTGGAAAGGCTGGAGCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT
GTGTGTGTGAGAGAGAGCCCTCCCACTGCCAGCTCAGGTTGTTCACAGATTTGGAATGGG
ACCAGAGGCCCTTGAAAATGTAATTGTGATTTACCTGTGCCAAAGGTGCTTTAAATGTCA
CATTTGTAAAGGGGAAGGCGGACAAGATTTGGAAGTTTAGTCACCTCTGAGCCACCCATC
ACCGCCAAAGTGTGGGGGAAGGATAGCTGCAGATTGACAGGCGAGGCTCAGAAACTCCTG
GCTTAGATTGAAGTGTGTGTGATGGGGGTGCAGCTTAGAGGACCCCCTCTGAAAGGGATG
GAGATGCTGATGAGAACAACACTACCACTTGAAGGTGAACATTCCCTGTCTGGTTGGACT
GAGTCAAGGGTCTGCGGTGCAGCATCTTCAGCTTGAGAAAATGAGGTTGTCAGTTTCCAG
CAAGGCTGACATCCACCAGACTGATTTCTCCGATGTTGCACTTGGCTGGCTTATGCCTCT
GAGATCGGTGCCACGGCTGTATTTATTTCAGTTGTCACTGCTGCTCCCTCCTGCTATGAA
ACGACACTGCCAGTGCCAGCAGTGTCCTTGGGAAAGGCAATATTTATGAAGGGCAGAAGA
GGCAGCCCCAAGAACCTAAAGACTGCAGGCTGCTAATTGCAGGAAATGACTTTGGAAGGG
CAGGCTCTTGTCCAGTTTCAGGGCTGAAATGCCTGGCGAACTCCATTCAGCCATCACATA
TTGACTGAGTGGCTGCTTAGCATGGGCCACCGCGCTAGGCTCGGGACAGCTGGTCTTTCC
GGCCATCTTTCTTGCTGGCAAGTCAGCAAACATTACCTTCTTAGTCACGTGCATATTTTT
GCCTTCATTCTTACCACCTGGCCTGCAAAGTTTGCAGGAGGGCCAGGTATATTCACTTGT
GTCTTCTGGGTCCTTTCATTGCTGACAGGCTGTGATGGCCCTCTTGAGCCTTGGGCAGGG
TGGGTGAGGTGCAGATGACCAGGAGTGTGTGAATGCCTTCCAGGAGGTGGCTTTGTTCCG
TGCCTCCCTGCCCCCATCGTCACTACCAGGTCTGGTACGGAGTCGGTGCTCAGTGTTTGC
AAAACAGAGCTGAAAACGGACTTTGGGAGGCCGAGGCAGGCAGATCACCTGAGGTCAGGA
GTTTGAGACCAGCCTGGTCAACATGGTAAAACCCCATTTCTGCTAAAAAAAAAAAAAAAA
AAAAAAAAAAAA
>OriGene 5' read for NM_052845.3 unedited
TGCATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGTCAAGCAGCCTG
GCTCATGGCTGTGTGCGGCCTGGGGAGCCGTCTTGGCCTGGGGAGCCGTCTTGGCCTGCG
CGGGTGCTTCGGCGCCGCCAGGCTCCTGTATCCCCGTTTCCAGAGCCGCGGCCCTCAGGG
CGTGGAAGACGGGGACAGGCCACAGCCTTCCTCGAAGACACCCAGGATCCCCAAGATTTA
CACCAAAACGGGAGACAAAGGGTTTTCTAGTACCTTCACAGGAGAAAGGAGACCCAAAGA
TGACCAAGTGTTTGAAGCCGTGGGAACTACAGATGAATTAAGTTCAGCTATTGGGTTTGC
TCTGGAATTAGTCACAGAAAAGGGCCATACATTTGCCGAAGAGCTTCAGAAAATCCAGTG
CACATTGCAGGACGTCGGCTCGGCCCTGGCGACACCATGCTCCTCGGCCCGGGAGGCTCA
CTTAAAGTATACCACGTTCAAGGCGGGGCCCATCCTGGAGCTGGAGCAGTGGATCGACAA
GTACACCAGCCAGCTCCCACCACTCACGGCCTTCATCCTGCCTTCGGGAGGCAAGATCAG
CTCGGCGCTGCATTTCTGCCGGGCCGTGTGCCGCCGGGCCGAGAGACGTGTGGTGCCTCT
TGTCCAGATGGGAGAGACCGATGCGAACGTGGCCAAGTTCTTAAACAGACTCAGTGACTA
TCTCTTCACGCTAGCCAGATATGCAGCCATGAAGAGGGAATCAAGAGAAAATATACATGA
AAAATGACCCATCGCCCGAGTCTGAGGGACTCTGAAATCACAGAAAGTGGGAGCTGAGAT
CCCTCATGGCGATGGCCGTGGAGAGAGGAGCTGCCTCTGGGTCCTGTCTGATGCCTCACC
CAAGAGCTCAAGCAGCTTTGTCCAGCTCAGCTTGATCTAACCCTCTGGCACTCTCAGAAC
TTGGAACCCTTTGGATTCTGTACTGACCTGCTCCAGCCTCTCCTGAC
Restriction Sites Please inquire     
ACCN NM_052845
ORF Size 753 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_052845.3, NP_443077.1
RefSeq Size 4154
RefSeq ORF 753
Locus ID 326625
Domains DUF80
Protein Pathways Metabolic pathways, Porphyrin and chlorophyll metabolism
Gene Summary This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found. [provided by RefSeq, Apr 2011]
Transcript Variant: This variant (1) encodes a functional protein.

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