Stanniocalcin 2 (STC2) (NM_003714) Human Untagged Clone

CAT#: SC320177

STC2 (untagged)-Human stanniocalcin 2 (STC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STC2
• Synonyms: STC-2; STCRP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003714.2 CATCCCTGCCATTGCCGGGCACTCGCGGCGCTGCTAACGGCCTGGTCACATGCTCTCCGG
  AGAGCTACGGGAGGGCGCTGGGTAACCTCTATCCGAGCCGCGGCCGCGAGGAGGAGGGAA
  AAGGCGAGCAAAAAGGAAGAGTGGGAGGAGGAGGGGAAGCGGCGAAGGAGGAAGAGGAGG
  AGGAGGAAGAGGGGAGCACAAAGGATCCAGGTCTCCCGACGGGAGGTTAATACCAAGAAC
  CATGTGTGCCGAGCGGCTGGGCCAGTTCATGACCCTGGCTTTGGTGTTGGCCACCTTTGA
  CCCGGCGCGGGGGACCGACGCCACCAACCCACCCGAGGGTCCCCAAGACAGGAGCTCCCA
  GCAGAAAGGCCGCCTGTCCCTGCAGAATACAGCGGAGATCCAGCACTGTTTGGTCAACGC
  TGGCGATGTGGGGTGTGGCGTGTTTGAATGTTTCGAGAACAACTCTTGTGAGATTCGGGG
  CTTACATGGGATTTGCATGACTTTTCTGCACAACGCTGGAAAATTTGATGCCCAGGGCAA
  GTCATTCATCAAAGACGCCTTGAAATGTAAGGCCCACGCTCTGCGGCACAGGTTCGGCTG
  CATAAGCCGGAAGTGCCCGGCCATCAGGGAAATGGTGTCCCAGTTGCAGCGGGAATGCTA
  CCTCAAGCACGACCTGTGCGCGGCTGCCCAGGAGAACACCCGGGTGATAGTGGAGATGAT
  CCATTTCAAGGACTTGCTGCTGCACGAACCCTACGTGGACCTCGTGAACTTGCTGCTGAC
  CTGTGGGGAGGAGGTGAAGGAGGCCATCACCCACAGCGTGCAGGTTCAGTGTGAGCAGAA
  CTGGGGAAGCCTGTGCTCCATCTTGAGCTTCTGCACCTCGGCCATCCAGAAGCCTCCCAC
  GGCGCCCCCCGAGCGCCAGCCCCAGGTGGACAGAACCAAGCTCTCCAGGGCCCACCACGG
  GGAAGCAGGACATCACCTCCCAGAGCCCAGCAGTAGGGAGACTGGCCGAGGTGCCAAGGG
  TGAGCGAGGTAGCAAGAGCCACCCAAACGCCCATGCCCGAGGCAGAGTCGGGGGCCTTGG
  GGCTCAGGGACCTTCCGGAAGCAGCGAGTGGGAAGACGAACAGTCTGAGTATTCTGATAT
  CCGGAGGTGAAATGAAAGGCCTGGCCACGAAATCTTTCCTCCACGCCGTCCATTTTCTTA
  TCTATGGACATTCCAAAACATTTACCATTAGAGAGGGGGGATGTCACACGCAGGATTCTG
  TGGGGACTGTGGACTTCATCGAGGTGTGTGTTCGCGGAACGGACAGGTGAGATGGAGACC
  CCTGGGGCCGTGGGGTCTCAGGGGTGCCTGGTGAATTCTGCACTTACACGTACTCAAGGG
  AGCGCGCCCGCGTTATCCTCGTACCTTTGTCTTCTTTCCATCTGTGGAGTCAGTGGGTGT
  CGGCCGCTCTGTTGTGGGGGAGGTGAACCAGGGAGGGGCAGGGCAAGGCAGGGCCCCCAG
  AGCTGGGCCACACAGTGGGTGCTGGGCCTCGCCCCGAAGCTTCTGGTGCAGCAGCCTCTG
  GTGCTGTCTCCGCGGAAGTCAGGGCGGCTGGATTCCAGGACAGGAGTGAATGTAAAAATA
  AATATCGCTTAGAATGCAGGAGAAGGGTGGAGAGGAGGCAGGGGCCGAGGGGGTGCTTGG
  TGCCAAACTGAAATTCAGTTTCTTGTGTGGGGCCTTGCGGTTCAGAGCTCTTGGCGAGGG
  TGGAGGGAGGAGTGTCATTTCTATGTGTAATTTCTGAGCCATTGTACTGTCTGGGCTGGG
  GGGGACACTGTCCAAGGGAGTGGCCCCTATGAGTTTATATTTTAACCACTGCTTCAAATC
  TCGATTTCACTTTTTTTATTTATCCAGTTATATCTACATATCTGTCATCTAAATAAATGG
  CTTTCAAACAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003714.2 unedited
  GGGAGTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCG
  AGGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGGACC
  GACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAA
  AACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCA
  CGAGGCATCCCTGCCATTGCCGGGCACTCGCGGCGCTGCTAACGGCCTGGTCACATGCTC
  TCCGGAGAGCTACGGGAGGGCGCTGGGTAACCTCTATCCGAGCCGCGGCCGCGAGGAGGA
  GGGAAAAGGCGAGCAAAAAGGAAGAGTGGGAGGAGGAGGGGAAGCGGCGAAGGAGGAAGA
  GGAGGAGGAGGAAGAGGGGAGCACAAAGGATCCAGGTCTCCCGACGGGAGGTTAATACCA
  AGAACCATGTGTGCCGAGCGGCTGGGCCAGTTCATGACCCTGGCTTTGGTGTTGGCCACC
  TTTGACCCGGCGCGGGGGACCGACGCCACCAACCCACCCGAGGGTCCCCAAGACAGGAGC
  TCCCAGCAGAAAGGCCGCCTGTCCCTGCAGAATACAGCGGAGATCCAGCACTGTTTGGTC
  AACGCTGGCGATGTGGGGTGTGGCGTGTTTGAATGTTTCGAGAACAACTCTTGTGAGATT
  CGGGGCTTACATGGGATTTGCATGACTTTTCTGCACAACGCTGGAAAATTTGATGCCCAG
  GGCAAGTCATTCATCAAGACGCCTTTGAAATGTAAGCCCACGCTCTGCGCACAGTTCGGC
  TGCATAAGCCGGAAGTGCCCGGCCATCAGGAATGGTGTCCCAGTGCAGCGGGAATGCTAC
  TCAAGCACGAACTGTGCGCCGCTGCCAGAGAAACCCCCGGGTGGATTAGTTGGGAGAATA
  GAATCCATTCCAGGA
• Restriction Sites: Please inquire
• ACCN: NM_003714
• ORF Size: 909 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003714.2, NP_003705.1
• RefSeq Size: 5361
• RefSeq ORF: 909
• Locus ID: 8614
• Domains: Stanniocalcin
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008]