WIPI2 (NM_016003) Human Untagged Clone

CAT#: SC320285

WIPI2 (untagged)-Human WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WIPI2
• Synonyms: ATG18B; Atg21; CGI-50; IDDSSA; WIPI-2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016003.3 CGGGTGCCCCGGCTCTGGAGCATAAACAAGAGCGGGGACGGGATGAGGCGGCGGTTGATC
  CCAGGGTGGCGAGTGGCGGCGACCGAGGCGGCGAGCGGGGCCCGGCGCCGACCCTGAGTG
  CAGCCTGACCCGCCCTCGCGCGCGCGCCCTCCCCGGCCGGGCCCACTCGCCGCGCGCCCA
  GCCATGAACCTGGCGAGCCAGAGCGGGGAGGCCGGCGCCGGCCAGCTGCTCTTCGCCAAC
  TTCAACCAGGACAACACGTCCCTAGCTGTTGGTAGTAAGTCCGGTTATAAATTTTTCTCC
  CTTTCTTCTGTGGATAAGCTGGAACAGATCTATGAATGCACCGATACGGAAGATGTGTGC
  ATTGTAGAGAGATTGTTCTCCAGCAGCCTAGTGGCCATCGTGAGCCTTAAAGCACCAAGG
  AAGCTAAAGGTTTGCCACTTTAAGAAGGGAACTGAGATCTGCAACTACAGCTACTCCAAC
  ACGATTCTGGCTGTGAAGCTCAACAGGCAGAGGCTGATAGTATGCCTGGAGGAGTCCCTG
  TACATCCACAACATTCGGGACATGAAGGTGCTGCATACGATCAGGGAGACGCCTCCAAAC
  CCTGCAGGCCTGTGTGCGCTGTCAATCAACAACGACAACTGCTACTTGGCGTACCCAGGG
  AGCGCGACCATCGGAGAGGTGCAGGTCTTCGATACCATTAATTTGAGAGCTGCAAACATG
  ATTCCGGCTCACGACAGTCCTTTAGCGGCACTGGCCTTTGACGCAAGTGGAACTAAACTT
  GCCACGGCTTCGGAGAAGGGGACCGTGATTAGGGTATTTTCCATTCCAGAAGGACAAAAA
  CTCTTTGAGTTTCGGAGAGGAGTAAAGAGGTGCGTGAGCATCTGCTCCCTGGCCTTCAGC
  ATGGACGGCATGTTCCTCTCCGCCTCCAGCAACACTGAGACCGTGCACATCTTCAAACTC
  GAGACTGTGAAAGAAAAACCCCCAGAGGAGCCCACCACCTGGACCGGGTACTTCGGGAAA
  GTGCTCATGGCCTCCACCAGCTACCTGCCTTCCCAAGTGACAGAAATGTTCAACCAGGGC
  AGAGCCTTCGCCACGGTCCGCCTGCCATTCTGCGGCCACAAAAACATCTGCTCGCTAGCC
  ACAATTCAGAAGATCCCGCGGTTGTTGGTGGGTGCCGCCGACGGGTACCTGTACATGTAC
  AACCTGGACCCCCAGGAGGGCGGCGAGTGTGCCCTGATGAAGCAGCACCGGCTGGACGGC
  AGTCTGGAAACGACCAATGAGATCTTGGACTCTGCCTCTCACGACTGCCCCTTAGTCACT
  CAGACATACGGCGCAGCTGCAGGAAAAGGTACTTACGTGCCTTCATCCCCAACGAGACTT
  GCCTACACAGACGACCTGGGTGCTGTGGGTGGCGCCTGCCTGGAGGACGAGGCCAGCGCC
  CTGCGCCTGGATGAGGACAGCGAGCACCCGCCCATGATTCTTCGGACTGACTGAACTTGA
  CCTGTGACCTCTGACCCGGGGAGCAGAGAACACTGGCTTCACAGAGGACTTTGTGCATTG
  CTGCTATGAACTTTGACCTGAGTCGGGGGAGAGGATGGCAGAGACTTTATTAAAAAAAAA
  AAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016003.3 unedited
  GTGGCCTCTGTGTAGACGACTCGATATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGT
  ACCGAGGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCG
  GACCGACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTT
  GTAAAACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTC
  GGCACGAGGCGGGTGCCCCGGCTCTGGAGCATAAACAAGAGCGGGGACGGGATGAGGCGG
  CGGTTGATCCCAGGGTGGCGAGTGGCGGCGTCCTAGGCGGCGAGCGGGGCCCGGCGCCGA
  CCCTGAGTGCAGCCTGACCCGCCCTCGCGCGCGCGCCCTCCCCGGCCGGGCCCACTCGCC
  GCGCGCCCAGCCATGAACCTGGCGAGCCAGAGCGGGGAGGCCGGCGCCGGCCAGCTGCTC
  TTCGCCAACTTCAACCAGGACAACACGTCCCTAGCTGTTGGTAGTAAGTCCGGTTATAAA
  TTTTTCTCCCTTTCTTCTGTGGATAAGCTGGAACAGATCTATGAATGCACCGATACGGAA
  GATGTGTGCATTGTAGAGAGATTGTTCTCCAGCAGCCTAGTGGCCATCGTGAGCCTTAAA
  GCACCAAGGAAGCTAAAGGTTTGCCACTTTAAGAAGGAAACTGAGATCTGCAACTACAGC
  TACTCCAACACGATTCTGGCTGTGAAGCTCAACAGGCAGAGGCTGATAGTATGCCTGGAG
  GAGTCCCTGTACATCCACAACATTCGGGACATGAAAGTGCTGCATACGATCAGGAGACGC
  TCCAAACCCTGCAGCCTGTGTGCGCTGTCATCAACACGACACTGCTACTTGCGTACCAAG
  GAGCGCGACATCGAAAGTGCAGTCTCGATACCATTATTTGAGAGCTGCAACATGAATTCG
  GCCTCACAGGAACAGGTCC
• Restriction Sites: Please inquire
• ACCN: NM_016003
• ORF Size: 1311 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016003.3, NP_057087.2
• RefSeq Size: 4435
• RefSeq ORF: 1311
• Locus ID: 26100
• Domains: WD40
• Gene Summary: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame 5' exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.