IL17RA (NM_014339) Human Untagged Clone

CAT#: SC320337

IL17RA (untagged)-Human interleukin 17 receptor A (IL17RA)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL17RA
• Synonyms: CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R; IMD51
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014339.4 GCGGAAAAGAAAGCCTCAGAACGTTCGCTCGCTGCGTCCCCAGCCGGGGCCGAGCCCTCC
  GCGACGCCACCCGGGCCATGGGGGCCGCACGCAGCCCGCCGTCCGCTGTCCCGGGGCCCC
  TGCTGGGGCTGCTCCTGCTGCTCCTGGGCGTGCTGGCCCCGGGTGGCGCCTCCCTGCGAC
  TCCTGGACCACCGGGCGCTGGTCTGCTCCCAGCCGGGGCTAAACTGCACGGTCAAGAATA
  GTACCTGCCTGGATGACAGCTGGATTCACCCTCGAAACCTGACCCCCTCCTCCCCAAAGG
  ACCTGCAGATCCAGCTGCACTTTGCCCACACCCAACAAGGAGACCTGTTCCCCGTGGCTC
  ACATCGAATGGACACTGCAGACAGACGCCAGCATCCTGTACCTCGAGGGTGCAGAGTTAT
  CTGTCCTGCAGCTGAACACCAATGAACGTTTGTGCGTCAGGTTTGAGTTTCTGTCCAAAC
  TGAGGCATCACCACAGGCGGTGGCGTTTTACCTTCAGCCACTTTGTGGTTGACCCTGACC
  AGGAATATGAGGTGACCGTTCACCACCTGCCCAAGCCCATCCCTGATGGGGACCCAAACC
  ACCAGTCCAAGAATTTCCTTGTGCCTGACTGTGAGCACGCCAGGATGAAGGTAACCACGC
  CATGCATGAGCTCAGGCAGCCTGTGGGACCCCAACATCACCGTGGAGACCCTGGAGGCCC
  ACCAGCTGCGTGTGAGCTTCACCCTGTGGAACGAATCTACCCATTACCAGATCCTGCTGA
  CCAGTTTTCCGCACATGGAGAACCACAGTTGCTTTGAGCACATGCACCACATACCTGCGC
  CCAGACCAGAAGAGTTCCACCAGCGATCCAACGTCACACTCACTCTACGCAACCTTAAAG
  GGTGCTGTCGCCACCAAGTGCAGATCCAGCCCTTCTTCAGCAGCTGCCTCAATGACTGCC
  TCAGACACTCCGCGACTGTTTCCTGCCCAGAAATGCCAGACACTCCAGAACCAATTCCGG
  ACTACATGCCCCTGTGGGTGTACTGGTTCATCACGGGCATCTCCATCCTGCTGGTGGGCT
  CCGTCATCCTGCTCATCGTCTGCATGACCTGGAGGCTAGCTGGGCCTGGAAGTGAAAAAT
  ACAGTGATGACACCAAATACACCGATGGCCTGCCTGTGGCTGACCTGATCCCCCCACCGC
  TGAAGCCCAGGAAGGTCTGGATCATCTACTCAGCCGACCACCCCCTCTACGTGGACGTGG
  TCCTGAAATTCGCCCAGTTCCTGCTCACCGCCTGCGGCACGGAAGTGGCCCTGGACCTGC
  TGGAAGAGCAGGCCATCTCGGAGGCAGGAGTCATGACCTGGGTGGGCCGTCAGAAGCAGG
  AGATGGTGGAGAGCAACTCTAAGATCATCGTCCTGTGCTCCCGCGGCACGCGCGCCAAGT
  GGCAGGCGCTCCTGGGCCGGGGGGCGCCTGTGCGGCTGCGCTGCGACCACGGAAAGCCCG
  TGGGGGACCTGTTCACTGCAGCCATGAACATGATCCTCCCGGACTTCAAGAGGCCAGCCT
  GCTTCGGCACCTACGTAGTCTGCTACTTCAGCGAGGTCAGCTGTGACGGCGACGTCCCCG
  ACCTGTTCGGCGCGGCGCCGCGGTACCCGCTCATGGACAGGTTCGAGGAGGTGTACTTCC
  GCATCCAGGACCTGGAGATGTTCCAGCCGGGCCGCATGCACCGCGTAGGGGAGCTGTCGG
  GGGACAACTACCTGCGGAGCCCGGGCGGCAGGCAGCTCCGCGCCGCCCTGGACAGGTTCC
  GGGACTGGCAGGTCCACTGTCCCGACTGGTTCGAATGTGAGAACCTCTACTCAGCAGATG
  ACCAGGATGCCCCGTCCCTGGACGAAGAGGTGTTTGAGGAGCCACTGCTGCCTCCGGGAA
  CCGGCATCGTGAAGCGGGCGCCCCTGGTGCGCGAGCCTGGCTCCCAGGCCTGCCTGGCCA
  TAGACCCGCTGGTCGGGGAGGAAGGAGGAGCAGCAGTGGCAAAGCTGGAACCTCACCTGC
  AGCCCCGGGGTCAGCCAGCGCCGCAGCCCCTCCACACCCTGGTGCTCGCCGCAGAGGAGG
  GGGCCCTGGTGGCCGCGGTGGAGCCTGGGCCCCTGGCTGACGGTGCCGCAGTCCGGCTGG
  CACTGGCGGGGGAGGGCGAGGCCTGCCCGCTGCTGGGCAGCCCGGGCGCTGGGCGAAATA
  GCGTCCTCTTCCTCCCTGTGGACCCCGAGGACTCGCCCCTTGGCAGCAGCACCCCCATGG
  CGTCTCCTGACCTCCTTCCAGAGGACGTGAGGGAGCACCTCGAAGGCTTGATGCTCTCGC
  TCTTCGAGCAGAGTCTGAGCTGCCAGGCCCAGGGGGGCTGCAGTAGACCCGCCATGGTCC
  TCACAGACCCACACACGCCCTACGAGGAGGAGCAGCGGCAGTCAGTGCAGTCTGACCAGG
  GCTACATCTCCAGGAGCTCCCCGCAGCCCCCCGAGGGACTCACGGAAATGGAGGAAGAGG
  AGGAAGAGGAGCAGGACCCAGGGAAGCCGGCCCTGCCACTCTCTCCCGAGGACCTGGAGA
  GCCTGAGGAGCCTCCAGCGGCAGCTGCTTTTCCGCCAGCTGCAGAAGAACTCGGGCTGGG
  ACACGATGGGGTCAGAGTCAGAGGGGCCCAGTGCATGAGGGCGGCTCCCCAGGGACCGCC
  CAGATCCCAGCCTTGAGAGAGGAGTGTGTGTGCACGTATTCATCTGTGTGTACATGTCTG
  CATGTGTATATGTTCGTGTGTGAAATGTAGGCTTTAAAATGTAAATGTCTGGATTTTAAT
  CCCAGGCATCCCTCCTAACTTTTCTTTGTGCAGCGGTCTGGTTATCGTCTATCCCCAGGG
  GAATCCACACAGCCCGCTCCCAGGAGCTAATGGTAGAGCGTCCTTGAGGCTCCATTATTC
  GTTCATTCAGCATTTATTGTGCACCTACTATGTGGCGGGCATTTGGGATACCAAGATAAA
  TTGCATGCGGCATGGCCCCAGCCATGAAGGAACTTAACCGCTAGTGCCGAGGACACATTA
  AACGAACAGGATGGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCACATTGGGAGGC
  CGAGGCAGGTGGATCACTCTGAGGTCAGGAGTTTGAGCCAGCCTGGCCAACATGGTGAAA
  CCCCATCTCCACTAAAAATAGAAAAATTAGCCGGGCATGGTGACACATGCCTGTAGTCCT
  AGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAATCTGGGAGGCAGAGGTTGCAGTG
  AGCCGAGATTGTGCCATTGCACTGCAGCCTGGATGACAGAGCGAGACTCTATCTCAAAAA
  AAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014339.4 unedited
  GAATTCTTTAGCACTCTGTATGCTTCCTCATGCCCCTTAAAAGGAAAACCCGACGGACCC
  GGCCCCGAGGAAAACCAGACGCCGCGATCGCGGCCCCCCAAATCTCAACCTTAACTATTT
  AGCGGACCGACCCGTTAACCGGCCGCAAATTCAAATCCACAAGTTTGTACAAAAAAGCAG
  GCTTGTAAAACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGA
  ATTCCGCACGACGGCGGAAAAGAAAGCCTCTAACGTTCGCTCGCTGCGTCCCCAGCCGGG
  GCCGAGCCCTCCGCGACGCCACCCGGGCCATGGGGGCCGTACGCAGCCCGCCGTCCGCTG
  TCCCGGGGCCCCTGCTGGGGCTGCTCCTGCTGCTCCTGGGCGTGCTGGCCCCGGGTGGCG
  CCTCCCTGCGACTCCTGGACCACCGGGCGCTGGTATGCTCCCACCCGGGGCTAAACTGCA
  CGGTCAATAATACTACCTGCCTGGATGACAAGCTGGATTCACCCTCAAAACCTGACCCCC
  CTCCTCCCCAAAGGACCTGCAGATCCAGCTGCACTTTGCCCACACCCAAACAAGAGAGAC
  CTGGTCCCCGTGGCTCACATCCCATGGTACACTGACACAGACGCCCAGCTTCCTGGACCC
  TCGAGGGGCCAGAGTTATTTGGCCCTGCAGCTGAACCACAATGGAAACGTTGGTGCGTCA
  AGGTATGGAGTTCAGTCCCAAACCTGAGGCAATCACCACAAGCGGGGGGCCGTTTTAACC
  TATCAACCCATTTTGGGGGTTAACCCTGGCACCAGAAATATATAAGGTGACCCTGTTCAC
  AACCC
• Restriction Sites: Please inquire
• ACCN: NM_014339
• ORF Size: 2601 bp
• Insert Size: 3373
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014339.4, NP_055154.3
• RefSeq Size: 3429
• RefSeq ORF: 2601
• Locus ID: 23765
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Gene Summary: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.