Apc11 (ANAPC11) (NM_001002244) Human Untagged Clone

CAT#: SC320636

ANAPC11 (untagged)-Human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANAPC11
• Synonyms: APC11; Apc11p; HSPC214
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001002244.1 GGCACGAGGGGCGGGCGCTGTTGAGGGAGTCGGGCCGCGACTGTGGTCGTTTTTATACCT
  TCCCGCGCGGACGCCGGCGCTGCCAACGGAAGGGCGGGTAGGGCGGTGCGTGATTAGGTT
  GGCGAAGGCTCTGCTGCCATGAAGGTGAAGATTAAGTGCTGGAACGGCGTGGCCACTTGG
  CTCTGGGTGGCCAACGATGAGAACTGTGGCATCTGCAGGATGGCATTTAACGGATGCTGC
  CCTGACTGTCCTCTCCATGGAGAAAGCATTTCTAGGTGTTTGGGCTGGTGCCCGCAGCCT
  GTGCCTGTCCTGGGAGGCAGGGCCCATCCACAGGTGCCCATCAACACAGCTTCCCCAACG
  CCTGGGCAGCACACCGGATCCCTGATGTCTAGGGAAGAGTCTTCTAGGTCCCCAGACCCC
  ACCCCTCCTGCCCTTGATCAAGAGACCAGTTCACTACTCAGATGCACGTCTCCTTGGTGC
  CTTGACCATTCATGTGACCTTTTTGGCATCACAGATCAAGTGTCTGCAGATGGGCCCAGG
  GCCTGTAGGCAAGGTGCCCGGCGACGACTGCCCGCTGGTGTGGGGCCAGTGCTCCCACTG
  CTTCCACATGCATTGCATCCTCAAGTGGCTGCACGCACAGCAGGTGCAGCAGCACTGCCC
  CATGTGCCGCCAGGAATGGAAGTTCAAGGAGTGAGGCCCGACCTGGCTCTCGCTGGAGGG
  GCATCCTGAGACTCCTTCCTCATGCTGGCGCCGATGGCTGCTGGGGACAGCGCCCCTGAG
  CTGCAACAAGGTGGAAACAAGGGCTGGAGCTGCGTTTGTTTTGCCATCACTATGTTGACA
  CTTTTATCCAATAAGTGAAAACTCATTAAACTACTCAAATCTTAAAAAAAAAAAAAAAAA
  A
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001002244.1 unedited
  GCCATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGGCGGGCGCTGTT
  GAGGGAGTCGGGCCGCGACTGTGGTCGTTTTTATACCTTCCCGCGCGGACGCCGGCGCTG
  CCAACGGAAGGGCGGGTAGGGCGGTGCGTGATTAGGTTGGCGAAGGCTCTGCTGCCATGA
  AGGTGAAGATTAAGTGCTGGAACGGCGTGGCCACTTGGCTCTGGGTGGCCAACGATGAGA
  ACTGTGGCATCTGCAGGATGGCATTTAACGGATGCTGCCCTGACTGTCCTCTCCATGGAG
  AAAGCATTTCTAGGTGTTTGGGCTGGTGCCCGCAGCCTGTGCCTGTCCTGGGAGGCAGGG
  CCCATCCACAGGTGCCCATCAACACAGCTTCCCCAACGCCTGGGCAGCACACCGGATCCC
  TGATGTCTAGGGAAGAGTCTTCTAGGTCCCCAGACCCCACCCCTCCTGCCCTTGATCAAG
  AGACCAGTTCACTACTCAGATGCACGTCTCCTTGGTGCCTTGACCATTCATGTGACCTTT
  TTGGCATCACAGATCAAGTGTCTGCAGATGGGCCCAGGGCCTGTAGGCAAGGTGCCCGGC
  GACGACTGCCCGCTGGTGTGGGGCCAGTGCTCCCACTGCTTCCACATGCATTGCATCCTC
  AAGTGGCTGCACGCACAGCAGGTGCAGCAGCACTGCCCCATGTGCCGCCAGGAATGGAAG
  TTCAGGAGTGAGGCCCGACCTGGCTCTCGCTGGAGGGCATCCTGAGACTCCTTCCTCATG
  CTGCGCCGATGGCTGCTGGGGACAGCGCCCCTGAGCTGCACCAGTGGAAACAAGGGCTAG
  AGCTGCGTTGTTGCCATCACTATGTTGACCTTTTATCCATAGTGAACTCTTAAACTACTC
  CAATTCTTACAAAAAAAAACCTC
• Restriction Sites: Please inquire
• ACCN: NM_001002244
• ORF Size: 591 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001002244.1, NP_001002244.1
• RefSeq Size: 1130
• RefSeq ORF: 591
• Locus ID: 51529
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
• Gene Summary: Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).