URP2 (FERMT3) (NM_031471) Human Untagged Clone

CAT#: SC320720

FERMT3 (untagged)-Human fermitin family member 3 (FERMT3), transcript variant URP2SF

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FERMT3
• Synonyms: KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031471, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGGGATGAAGACAGCCTCCGGGGACTACATCGACTCGTCATGGGAGCTGCGGGTGTTTGTGGGAG
  AGGAGGACCCAGAGGCCGAGTCGGTCACCCTGCGGGTCACTGGGGAGTCGCACATCGGCGGGGTGCTCCT
  GAAGATTGTGGAGCAGATCAATCGCAAGCAGGACTGGTCAGACCATGCTATTTGGTGGGAACAGAAGAGG
  CAGTGGCTGCTGCAGACCCACTGGACACTGGACAAGTACGGGATCCTGGCCGACGCACGCCTCTTCTTTG
  GGCCCCAGCACCGGCCCGTCATCCTTCGGTTGCCCAACCGCCGCGCACTGCGCCTCCGTGCCAGCTTCTC
  CCAGCCCCTCTTCCAGGCTGTGGCTGCCATCTGCCGCCTCCTCAGCATCCGGCACCCCGAGGAGCTGTCC
  CTGCTCCGGGCTCCTGAGAAGAAGGAGAAGAAGAAGAAAGAGAAGGAGCCAGAGGAAGAGCTCTATGACT
  TGAGCAAGGTTGTCTTGGCTGGGGGCGTGGCACCTGCACTGTTCCGGGGGATGCCAGCTCACTTCTCGGA
  CAGCGCCCAGACTGAGGCCTGCTACCACATGCTGAGCCGGCCCCAGCCGCCACCCGACCCCCTCCTGCTC
  CAGCGTCTGCCACGGCCCAGCTCCCTGTCAGACAAGACCCAGCTCCACAGCAGGTGGCTGGACTCGTCGC
  GGTGTCTCATGCAGCAGGGCATCAAGGCCGGGGACGCACTCTGGCTGCGCTTCAAGTACTACAGCTTCTT
  CGATTTGGATCCCAAGACAGACCCCGTGCGGCTGACACAGCTGTATGAGCAGGCCCGGTGGGACCTGCTG
  CTGGAGGAGATTGACTGCACCGAGGAGGAGATGATGGTGTTTGCCGCCCTGCAGTACCACATCAACAAGC
  TGTCCCAGAGCGGGGAGGTGGGGGAGCCGGCTGGCACAGACCCAGGGCTGGACGACCTGGATGTGGCCCT
  GAGCAACCTGGAGGTGAAGCTGGAGGGGTCGGCGCCCACAGATGTGCTGGACAGCCTCACCACCATCCCA
  GAGCTCAAGGACCATCTCCGAATCTTTCGGCCCCGGAAGCTGACCCTGAAGGGCTACCGCCAACACTGGG
  TGGTGTTCAAGGAGACCACACTGTCCTACTACAAGAGCCAGGACGAGGCCCCTGGGGACCCCATTCAGCA
  GCTCAACCTCAAGGGCTGTGAGGTGGTTCCCGATGTTAACGTCTCCGGCCAGAAGTTCTGCATTAAACTC
  CTAGTGCCCTCCCCTGAGGGCATGAGTGAGATCTACCTGCGGTGCCAGGATGAGCAGCAGTATGCCCGCT
  GGATGGCTGGCTGCCGCCTGGCCTCCAAAGGCCGCACCATGGCCGACAGCAGCTACACCAGCGAGGTGCA
  GGCCATCCTGGCCTTCCTCAGCCTGCAGCGCACGGGCAGTGGGGGCCCGGGCAACCACCCCCACGGCCCT
  GATGCCTCTGCCGAGGGCCTCAACCCCTACGGCCTCGTTGCCCCCCGTTTCCAGCGAAAGTTCAAGGCCA
  AGCAGCTCACCCCACGGATCCTGGAAGCCCACCAGAATGTGGCCCAGTTGTCGCTGGCAGAGGCCCAGCT
  GCGCTTCATCCAGGCCTGGCAGTCCCTGCCCGACTTCGGCATCTCCTATGTCATGGTCAGGTTCAAGGGC
  AGCAGGAAAGACGAGATCCTGGGCATCGCCAACAACCGACTGATCCGCATCGACTTGGCCGTGGGCGACG
  TGGTCAAGACCTGGCGTTTCAGCAACATGCGCCAGTGGAATGTCAACTGGGACATCCGGCAGGTGGCCAT
  CGAGTTTGATGAACACATCAATGTGGCCTTCAGCTGCGTGTCTGCCAGCTGCCGAATTGTACACGAGTAT
  ATCGGGGGCTACATTTTCCTGTCGACGCGGGAGCGGGCCCGTGGGGAGGAGCTGGATGAAGACCTCTTCC
  TGCAGCTCACCGGGGGCCATGAGGCCTTCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_031471.4 unedited
  CCCATTTGTATACGACTCCTATAGGGCGGCCGGGAATCGGCACGAGGGAAAGGAGGGCAG
  GAAGCCCACGGCCCACAGGGGTGTAGCCCGAGACCCACCTGCAGCCCCCAGCCCTTGCCA
  GGAAAGCAGCAGCCGCAGCCATGGCGGGGATGAAGACAGCCTCCGGGGACTACATCGACT
  CGTCATGGGAGCTGCGGGTGTTTGTGGGAGAGGAGGACCCAGAGGCCGAGTCGGTCACCC
  TGCGGGTCACTGGGGAGTCGCACATCGGCGGGGTGCTCCTGAAGATTGTGGAGCAGATCA
  ATCGCAAGCAGGACTGGTCAGACCTTGCTATTTGGTGGGAACAGAAGAGGCAGTGGCTGC
  TGCAGACCCACTGGACACTGGACAAGTACTGTATCCTGGCCGACGCACGCCTCTTCTTTG
  GGCCCTAACACCGGCC
• Restriction Sites: Please inquire
• ACCN: NM_031471
• ORF Size: 1992 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031471.4, NP_113659.3
• RefSeq Size: 2506
• RefSeq ORF: 1992
• Locus ID: 83706
• Domains: B41, PH
• Gene Summary: Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]
  Transcript Variant: This variant (URP2SF) uses an alternate in-frame splice junction at the 5' end of a coding exon compared to variant URP2LF. The resulting isoform (short isoform) has the same N- and C-termini but is shorter compared to the long isoform.