GNAI3 (NM_006496) Human Untagged Clone

CAT#: SC320804

GNAI3 (untagged)-Human guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GNAI3
• Synonyms: 87U6; ARCND1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006496.1 AGCTGACGGAGAGGGCCACCGCCCAGCAATAGACGGTGCCTCAGCCTGCCGAGCCGCAGT
  TTCCGTGGTGTGAGTGAGTCCGGGCCCGTGTCCCCTCTCCCGCCGCCGCCATGGGCTGCA
  CGTTGAGCGCCGAAGACAAGGCGGCAGTGGAGCGAAGCAAGATGATCGACCGCAACTTAC
  GGGAGGACGGGGAAAAAGCGGCCAAAGAAGTGAAGCTGCTGCTACTCGGTGCTGGAGAAT
  CTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGATGGCTATTCAGAGG
  ATGAATGTAAACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCCATCATTGCAA
  TCATAAGAGCCATGGGACGGCTAAAGATTGACTTTGGGGAAGCTGCCAGGGCAGATGATG
  CCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATGACTCCAGAACTAG
  CAGGAGTGATTAAACGGTTATGGCGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCA
  GGGAATATCAGCTCAATGATTCTGCTTCATATTATCTAAATGATCTGGATAGAATATCCC
  AGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTGAAGACCACAGGCA
  TTGTAGAAACACATTTCACCTTCAAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCC
  AAAGATCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGGAGTGACAGCAATTATCTTCT
  GTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAGATGAACCGAATGC
  ATGAAAGCATGAAACTGTTTGACAGCATTTGTAATAACAAATGGTTTACAGAAACTTCAA
  TCATTCTCTTCCTTAACAAGAAAGACCTTTTTGAGGAAAAAATAAAGAGGAGTCCGTTAA
  CTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCAGCTGCCTATATTC
  AATGCCAGTTTGAAGATCTGAACAGAAGAAAAGATACCAAGGAGATCTATACTCACTTCA
  CCTGTGCCACAGACACGAAGAATGTGCAGTTTGTTTTTGATGCTGTTACAGATGTCATCA
  TTAAAAACAACTTAAAGGAATGTGGACTTTATTGAGAAGCATGGATGTTAGTGAAAGTTA
  CTACAGTGTGGAGTGTTGAGACCAGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCA
  TGAACGGGACCAGGGAATGGCAGCAGCATGCAGAATCTTAGCACTCTTTAGCACAATATT
  TTGTATTAGGGAACTTTTAATTGACATGAGATGCTAAAGTCAGACATTGGAATTGGAAGA
  ACTATAAAGTGTGATTCGATCGTCAAGACATCACTTGGATTTCTTAATCTTAAATGCTTA
  TGGAAGATGTGAAGTTGAGGTGCTGCATTCTAGAACTTCAATATGTAGCTTACTCTTTTT
  TTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTTAAGGTTTTTTCATCAAGAGAAGAAT
  AACTTTACTAAATTTTATTTCTTTATTTGCAAAAGAATCTTTATTAAAACAAACAATCTT
  AACTATGCACATGATGTGACCAGATCATCTTGAAAATATTCCTCTTTAGTAGGAACTCTT
  TGTTTTTAACTCTTGGTATGGTCAGAATATAATACTTCCATAATTACTTATAATTCTTTC
  CGGTTACTGGGGCTATAAATACAACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAA
  AGTACCATTATGGTTTCCATATGGTAATTACATTGGAAAGTTCTGCAATAAGATTCTAGT
  TCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAACCTTGTTTGTGCAGATTACCAAATT
  ACTGCTGATGTAGTATGATAAAGTCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGC
  CAATCAGAAATGCAAATTGCTAAATTCCAAACAGAACCAGTGACTTTGCTGCTACATATT
  TACTAAATTGACCACTTTGATTCTTGCTTGTTTGTCTCAGTTATAGGGAGTTTTGTACAT
  GGTGCCTCTTGTTTTCCATCTTCATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTA
  ACAGTGCATGCTTTTACTTTGTAAATGTGGTGCCAAATCCCTGTTTGCCATCGTTTTTAC
  TGTACCGATGTTAACTGTAGTAATCCTTAGCCAGTATGTTCTTTTGCTGAAACTGTTGCA
  TTTTGGGACTTTTTTCCACTTTGTCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCA
  GTATTAAAATGGTGAGTAAAGAGCCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_006496
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006496.1, NP_006487.1
• RefSeq Size: 3143 bp
• RefSeq ORF: 1065 bp
• Locus ID: 2773
• Cytogenetics: 1p13.3
• Domains: G-alpha
• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction
• Gene Summary: 'Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012]'